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Saint Charles Area Rentals

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Results: 258 Rentals

  • The Hill House Getaway: 4BR Retreat
    From $503 per night (USD)

    VRBO

    The Hill House Getaway: 4BR Retreat

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    9

    Welcome to our charming 4-bedroom, 3-bathroom home located in the heart of St. Charles, MO! Just 500 feet from historic ...

    From $503 per night (USD)

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    Details
  • Delightful Home near Downtown St. Charles with Garage
    From $130 per night (USD)

    Expedia

    Delightful Home near Downtown St. Charles with Garage

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Welcome to this beautiful and quaint home in a quite neighborhood of St. Charles. You are just minutes from historic do ...

    From $130 per night (USD)

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    Details
  • Quiet St Charles Cottage w\/ Patio & 4 Acres
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    Quiet St Charles Cottage w\/ Patio & 4 Acres

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    8

    Get away from stress and worries when you stay at this charming vacation rental in Saint Charles! Built in the 1930s, th ...

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  • Peaceful 2 Bedroom Next to Park!
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    Expedia

    Peaceful 2 Bedroom Next to Park!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    This peaceful, newly renovated unit is perfect for your getaway! It has a fully stocked coffee bar and kitchen, a large ...

    Click For Pricing

    Expedia

    Details
  • Cozy Camp Cottage at Glamping St. Louis
    From $88 per night (USD)

    VRBO

    Cozy Camp Cottage at Glamping St. Louis

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    5

    Get away and experience the tranquility of nature in a cozy camp cottage in a secluded campsite. The Camp Cottage offers ...

    From $88 per night (USD)

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    Details
  • Tiny Off Grid A-Frame Cottage - Glamping St. Louis
    From $80 per night (USD)

    VRBO

    Tiny Off Grid A-Frame Cottage - Glamping St. Louis

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Get away and experience the tranquility of nature in a tiny A-frame cottage in a private campsite. The A-frame cottage o ...

    From $80 per night (USD)

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    Details
  • ☆BackYard BBQ Hidden Gem☆Perfect Location~Groups \/Pets Welcome
    From $219 per night (USD)

    VRBO

    ☆BackYard BBQ Hidden Gem☆Perfect Location~Groups \/Pets Welcome

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    16

    Interior Remodel completed. This home includes everything you will need for your stay. Beds are extremely Comfortable ...

    From $219 per night (USD)

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    Details
  • 🌷RARE NEW TREASURE🌷2 Homes+Outdoor Gathering Area. Two Blocks From Main St.!!!
    From $632 per night (USD)

    Expedia

    🌷RARE NEW TREASURE🌷2 Homes+Outdoor Gathering Area. Two Blocks From Main St.!!!

    Bedrooms:
    3
    Bathrooms:
    5
    Sleeps:
    22

    Recent review. "This place is a rarity in Vrbo - it’s better than than it’s described. Space is huge." Seeking a large ...

    From $632 per night (USD)

    Expedia

    Details
  • ✨️Cozy Quaint 1st Floor Pet Friendly🐶
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    ✨️Cozy Quaint 1st Floor Pet Friendly🐶

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    6

    Soak up the vibes of both St. Louis and St. Charles County. You'll have 2 comfy queen size beds and 2 bathrooms. There i ...

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    Details
  • St. Charles 1860's Gem - Sleeps 6!
    From $115 per night (USD)

    Expedia

    St. Charles 1860's Gem - Sleeps 6!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    8

    10-foot ceilings and exposed brick walls! Brand new bath & a full kitchen for homemade meals! Plenty of natural light, s ...

    From $115 per night (USD)

    Expedia

    Details
  • Spacious home in Historic St. Charles, Near Main Street + self-serve breakfast
    From $240 per night (USD)

    VRBO

    Spacious home in Historic St. Charles, Near Main Street + self-serve breakfast

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Welcome to Clark Corner Guest House - the perfect place for your vacation! Enjoy the small town feel of downtown St. Ch ...

    From $240 per night (USD)

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    Details
  • 4 Bedrooms and a Fire Pit; St. Charles, MO
    From $242 per night (USD)

    Expedia

    4 Bedrooms and a Fire Pit; St. Charles, MO

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    10

    Spacious, 4 bedroom home 3 blocks from Main Street St. Charles that sleeps 10 in beds! Enjoy the backyard fire pit, 3 ca ...

    From $242 per night (USD)

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    Details
  • 2 Bed Townhome Getaway with Backyard and Laundry
    From $160 per night (USD)

    VRBO

    2 Bed Townhome Getaway with Backyard and Laundry

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    5

    Two Story, Two bedroom, One and a half bath townhome available within walking distance of Streets of St. Charles. Enjoy ...

    From $160 per night (USD)

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    Details
  • Fresh & Modern Home-Away-From-Home Near St Charles
    From $202 per night (USD)

    Expedia

    Fresh & Modern Home-Away-From-Home Near St Charles

    Bedrooms:
    1
    Bathrooms:
    3
    Sleeps:
    10

    Explore the city, then make yourself at home at this modern rental just 12 minutes from St. Charles and a half hour from ...

    From $202 per night (USD)

    Expedia

    Details
  • St. Charles, MO house with Private Patio
    From $271 per night (USD)

    VRBO

    St. Charles, MO house with Private Patio

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    Stay in this charming Two bedroom, One bath home built in 1908 just 0.5 miles away from Main Street St. Charles! The hou ...

    From $271 per night (USD)

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    Details
  • Prime Loft of Main Street
    From $119 per night (USD)

    Expedia

    Prime Loft of Main Street

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    6

    Historic loft centrally located along the St. Charles riverfront, on the north end of Main Street and just south of Fren ...

    From $119 per night (USD)

    Expedia

    Details
  • 1920's Vintage Home in Historic Saint Charles - Fully Remodeled
    From $107 per night (USD)

    VRBO

    1920's Vintage Home in Historic Saint Charles - Fully Remodeled

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    Newly renovated 3-bedroom, 2 full bath - minutes from Historic St. Charles Main Street, Lindenwood, Ameristar and many o ...

    From $107 per night (USD)

    VRBO

    Details
  • Amazing historic home from 1860!
    From $110 per night (USD)

    Expedia

    Amazing historic home from 1860!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Historic 1860's Home! Newly renovated 2-bedroom, 1 full bath - minutes from Historic St. Charles Main Street, Lindenwood ...

    From $110 per night (USD)

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    Details
  • ‘The Ruebling House’ Cozy 2nd-Floor Apartment!
    From $176 per night (USD)

    VRBO

    ‘The Ruebling House’ Cozy 2nd-Floor Apartment!

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    6

    Avoid the crowds of St. Louis when you escape to Defiance, the ideal spot to access Missouri’s finest wineries. Let the ...

    From $176 per night (USD)

    VRBO

    Details
  • 'The Ruebling House': Bright, Modern, & Renovated!
    From $181 per night (USD)

    Expedia

    'The Ruebling House': Bright, Modern, & Renovated!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Ideal for a retreat from city life, this 2-bedroom, 1-bathroom vacation rental is a relaxing getaway! Located in the his ...

    From $181 per night (USD)

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    Details
  • 'The Ruebling House' Historic Defiance Apartment!
    From $168 per night (USD)

    VRBO

    'The Ruebling House' Historic Defiance Apartment!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Leave the hustle and bustle of city life behind when you escape to The Farmhouse, a 2-bedroom, 1-bathroom vacation renta ...

    From $168 per night (USD)

    VRBO

    Details
  • Spacious*Outdoor Space*Modern*Family*Groups*Modern*Artistic
    From $229 per night (USD)

    Expedia

    Spacious*Outdoor Space*Modern*Family*Groups*Modern*Artistic

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    13

    Enjoy a stylish experience at this super conveniently-located home in the St. Louis suburbs! This unique and private 4 b ...

    From $229 per night (USD)

    Expedia

    Details
  • 1 Bedroom | Pool & Gym. Free Breakfast
    From $169 per night (USD)

    VRBO

    1 Bedroom | Pool & Gym. Free Breakfast

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    This 1-bedroom condo in O'Fallon, It's close to the Busch Conservation Area, Progress West Hospital, and Hollywood Casin ...

    From $169 per night (USD)

    VRBO

    Details
  • Fenced Yard*Family*Pet Friendly*2 Garage*Professionally Decorated*Open*Bright*
    From $199 per night (USD)

    Expedia

    Fenced Yard*Family*Pet Friendly*2 Garage*Professionally Decorated*Open*Bright*

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    This home is not just a restful retreat but a curated experience! The space is professionally designed and is the ideal ...

    From $199 per night (USD)

    Expedia

    Details
  • Hillside Cabin on 43 Acres w\/ Private Lake & View!
    From $216 per night (USD)

    VRBO

    Hillside Cabin on 43 Acres w\/ Private Lake & View!

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Free from modern distractions, this 1-bedroom, 1-bath cabin in the heart of wine country is the perfect place to unplug ...

    From $216 per night (USD)

    VRBO

    Details
  • NEWLY REMODELED-Treasure of Lindenwood\/Main Street St Charles
    From $209 per night (USD)

    Expedia

    NEWLY REMODELED-Treasure of Lindenwood\/Main Street St Charles

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    20

    This treasure is surrounded by vintage homes and neighborhoods that fit with the history of downtown Saint Charles. It w ...

    From $209 per night (USD)

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    Details
  • Fresh&Mondern-1\/2 mile from STC Convention Center
    From $139 per night (USD)

    VRBO

    Fresh&Mondern-1\/2 mile from STC Convention Center

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Explore the city, then make yourself at home at this modern home in St. Charles that's only 11 minutes or 8.5 miles from ...

    From $139 per night (USD)

    VRBO

    Details
  • Cozy Augusta Home w\/ Porch: Walk to Katy Trail!
    From $185 per night (USD)

    Expedia

    Cozy Augusta Home w\/ Porch: Walk to Katy Trail!

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    This bright, well-appointed Augusta home offers an idyllic getaway in the heart of the Missouri Rhineland! The 3-bedroom ...

    From $185 per night (USD)

    Expedia

    Details
  • Clark Brick House w\/ Pool - Historic St. Charles
    From $290 per night (USD)

    VRBO

    Clark Brick House w\/ Pool - Historic St. Charles

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    10

    The Clark Brick House is a spacious (2700 sq/ft), modern, and fun place for your visit to St. Charles. The house offers ...

    From $290 per night (USD)

    VRBO

    Details
  • Secluded Glamping Tent at Glamping St. Louis
    From $100 per night (USD)

    VRBO

    Secluded Glamping Tent at Glamping St. Louis

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    5

    Get away and experience the tranquility of nature in a secluded glamping tent that is just steps from our hidden pond. ...

    From $100 per night (USD)

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    Details
  • Beautiful and Spacious Family Home Near OldTown with Theater
    From $189 per night (USD)

    VRBO

    Beautiful and Spacious Family Home Near OldTown with Theater

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    Winner of Airbnb's "Top New Host in Missouri" award for 2021, La Maison Charbonneau is a stylishly renovated century-old ...

    From $189 per night (USD)

    VRBO

    Details
  • Rustic Handcrafted Japanese-Style Home by OldTown, Three Bedrooms, Theater Room
    From $247 per night (USD)

    Expedia

    Rustic Handcrafted Japanese-Style Home by OldTown, Three Bedrooms, Theater Room

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    6

    Enter into the tranquility of a Japanese-style home interior near historic Old Town St Charles. The house is a symphony ...

    From $247 per night (USD)

    Expedia

    Details
  • 😉St. Charles Central Oasis-Large
    From $287 per night (USD)

    VRBO

    😉St. Charles Central Oasis-Large

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    20

    Welcome to your cozy yet large home that is perfect for any size group. When we say the house is stocked, it is fully lo ...

    From $287 per night (USD)

    VRBO

    Details
  •  Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
    From $159 per night (USD)

    Expedia

    Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

    Bedrooms:
    1
    Bathrooms:
    3
    Sleeps:
    6

    Our cozy home is only 8 blocks from historic Main Street. Is easily accessible from the highlights of St. Charles. Main ...

    From $159 per night (USD)

    Expedia

    Details
  • Sweet Escape Near Historic Main Street & MO River
    From $165 per night (USD)

    VRBO

    Sweet Escape Near Historic Main Street & MO River

    Bedrooms:
    1
    Bathrooms:
    4
    Sleeps:
    8

    Find a sweet escape in a remodeled bungalow! Walk to Main Street in 15 minutes! This 4-bedroom house is the perfect loca ...

    From $165 per night (USD)

    VRBO

    Details
  • Vintage French Beauty - Newly Renovated & Spacious
    From $98 per night (USD)

    Expedia

    Vintage French Beauty - Newly Renovated & Spacious

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    Newly renovated 3-bedroom, 2 full bath minutes from Historic St. Charles Main Street, Lindenwood, Ameristar and many oth ...

    From $98 per night (USD)

    Expedia

    Details
  • The  Cardinal Nest A Cozy Cottage on Historic Main Street; Pet Friendly
    From $108 per night (USD)

    VRBO

    The Cardinal Nest A Cozy Cottage on Historic Main Street; Pet Friendly

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    The Cardinal nest is the perfect place to lay your head if you are in town for a wedding, work, visiting family and fri ...

    From $108 per night (USD)

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    Details
  • Residence on the Roundabout
    From $157 per night (USD)

    Expedia

    Residence on the Roundabout

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    New Listing. 1940's Brick Residence in Historic Frenchtown Neighborhood. Whole house with 2 Bedrooms King Bed in each. ...

    From $157 per night (USD)

    Expedia

    Details
  • 🐕Pet friendly ❤Midwest Desert🏜\/2 bed 2 bath\/ Pool\/ 1st Floor
    Click For Pricing

    Expedia

    🐕Pet friendly ❤Midwest Desert🏜\/2 bed 2 bath\/ Pool\/ 1st Floor

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    6

    Have fun with family and friends at this stylish 2 bedroom 2 bathroom 1st FLOOR unit. Enjoy the comfort and convenience ...

    Click For Pricing

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    Details
  • Private St Peters Home\/Patio\/BBQ\/ Pool Table
    From $260 per night (USD)

    Expedia

    Private St Peters Home\/Patio\/BBQ\/ Pool Table

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    10

    Located in a quiet neighborhood and just a short drive to Busch Stadium, St.Louis Science Center, City Museum, Botanical ...

    From $260 per night (USD)

    Expedia

    Details
  • Overlook Main St. in this 2 bedroom owners suite!
    From $95 per night (USD)

    VRBO

    Overlook Main St. in this 2 bedroom owners suite!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    5

    Come enjoy the perfect getaway spot. You will enjoy river front views, popular shops and restaurants, night scene (all w ...

    From $95 per night (USD)

    VRBO

    Details
  • HUGE 2 bedroom unit on Main Street
    From $154 per night (USD)

    Expedia

    HUGE 2 bedroom unit on Main Street

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    5

    This unit is located on the historic cobblestone Main Street, right next to one of the best local coffee shops in town! ...

    From $154 per night (USD)

    Expedia

    Details
  • THE MADISON HOUSE #1 - HISTORIC AREA in ST CHARLES
    From $225 per night (USD)

    VRBO

    THE MADISON HOUSE #1 - HISTORIC AREA in ST CHARLES

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    8

    This townhouse is located in the Historic District of St. Charles MO. House is located a few blocks away from Main St, ...

    From $225 per night (USD)

    VRBO

    Details
  • ‘Bross Brother's Cabin’ w\/ Wraparound Porch!
    From $328 per night (USD)

    Expedia

    ‘Bross Brother's Cabin’ w\/ Wraparound Porch!

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    8

    This 2-bedroom, 2-bathroom vacation rental is an iconic restored log cabin, original to the town of Cottleville! Perfect ...

    From $328 per night (USD)

    Expedia

    Details
  • Central Luxe 5br Home - Hot Tub & Views - 🥂 🍷\n
    From $300 per night (USD)

    VRBO

    Central Luxe 5br Home - Hot Tub & Views - 🥂 🍷\n

    Bedrooms:
    4
    Bathrooms:
    5
    Sleeps:
    12

    Relax while you overlook the Katy Trail, enjoy incredible views, and are within WALKING distance of Good News Brewery, M ...

    From $300 per night (USD)

    VRBO

    Details
  • Main Street Living!  2 Bedroom Unit right On Main!
    From $102 per night (USD)

    Expedia

    Main Street Living! 2 Bedroom Unit right On Main!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Come enjoy Main Street Living Right on Main Street, directly above a Wine Cafe in the original Customs House in St. Char ...

    From $102 per night (USD)

    Expedia

    Details
  • Blair's House on St. Joseph - 3Bed 1.5Bath
    From $169 per night (USD)

    VRBO

    Blair's House on St. Joseph - 3Bed 1.5Bath

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Summary: Welcome to Blairs House on St. Joseph in O'Fallon, MO an absolute guest favorite! Where we ensure you have a c ...

    From $169 per night (USD)

    VRBO

    Details
  • Golf Heaven and Nature Lovers
    From $350 per night (USD)

    Expedia

    Golf Heaven and Nature Lovers

    Bedrooms:
    4
    Bathrooms:
    4
    Sleeps:
    8

    Lovely two story home with the master bedroom on the main floor, It has a TV separate shower and jacuzzi tub with double ...

    From $350 per night (USD)

    Expedia

    Details
  • Amazing Renovated Historic Loft on Main Street
    From $129 per night (USD)

    VRBO

    Amazing Renovated Historic Loft on Main Street

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    6

    Historic loft centrally located along the St. Charles riverfront, on the north end of Main Street and just south of Fren ...

    From $129 per night (USD)

    VRBO

    Details
  • Pool & Gym. Your Next Trip!
    From $233 per night (USD)

    Expedia

    Pool & Gym. Your Next Trip!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Sleeps up to 6 (Max 6 adults). It's close to the Busch Conservation Area, Progress West Hospital, and Hollywood Casino ...

    From $233 per night (USD)

    Expedia

    Details
  • Main Street Balcony Apartment!
    From $268 per night (USD)

    VRBO

    Main Street Balcony Apartment!

    Bedrooms:
    3
    Bathrooms:
    2
    Sleeps:
    5

    Upstairs Main Street apartment that can host up to 5 guests. With a full parade balcony with lounge seating to sit back, ...

    From $268 per night (USD)

    VRBO

    Details
  • The Original Custom House!
    From $96 per night (USD)

    Expedia

    The Original Custom House!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Come stay in what was St. Charles original Customs House built in 1801, but fully stocked with modern amenities and comf ...

    From $96 per night (USD)

    Expedia

    Details
  • In the Heart of Night Life
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    Expedia

    In the Heart of Night Life

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    This cozy and convenient retreat, is just steps away from the vibrant Main St. Saint Charles. Immerse yourself in the li ...

    Click For Pricing

    Expedia

    Details
  • Views of the River from the Top!
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    Expedia

    Views of the River from the Top!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    ​​​​​​Welcome to the heart of Main Street St. Charles, where history and modern comfort converge! We are excited to intr ...

    Click For Pricing

    Expedia

    Details
  • 1 Bed 1 Bath on Main Top Floor Apartment
    Click For Pricing

    Expedia

    1 Bed 1 Bath on Main Top Floor Apartment

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    6

    Indulge in a serene and stylish retreat in this inviting space, where you can kick back and relax. This charming getaway ...

    Click For Pricing

    Expedia

    Details
  • 🎗Katytrail\/Pet friendly❤\/St.Charles\/PowerPlex\/St.Louis\/Winery🐕👍🏼\/Fireplace
    Click For Pricing

    Expedia

    🎗Katytrail\/Pet friendly❤\/St.Charles\/PowerPlex\/St.Louis\/Winery🐕👍🏼\/Fireplace

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    6

    This 2 bedroom 2 bathroom apartment is comfortable, stylish, private and convenient. You will be located in the back on ...

    Click For Pricing

    Expedia

    Details
  • The Cozy home near Main Street St Charles w\/ patio Bbq about 10min\/ airport.
    From $94 per night (USD)

    VRBO

    The Cozy home near Main Street St Charles w\/ patio Bbq about 10min\/ airport.

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    6

    The charming cozy home built in 1930 in historic Old Towne neighborhood of St. Charles. People are friendly, area is saf ...

    From $94 per night (USD)

    VRBO

    Details
  • 4 bedroom Oasis with Pool in\nQuiet Neighborhood
    From $133 per night (USD)

    Expedia

    4 bedroom Oasis with Pool in\nQuiet Neighborhood

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    7

    Welcome to my quiet, friendly, & tranquil neighborhood. Recently updated rooms, bathrooms and common areas. Located upst ...

    From $133 per night (USD)

    Expedia

    Details
  • Great group getaway!
    From $390 per night (USD)

    VRBO

    Great group getaway!

    Bedrooms:
    4
    Bathrooms:
    4
    Sleeps:
    12

    This awesome bunkhouse sleeps up to 10 very comfortably with 2 large great rooms for eating, playing cards, hanging out ...

    From $390 per night (USD)

    VRBO

    Details
  • Cozy & Classic in St. Charles, 5 Mins. to Main St!
    From $179 per night (USD)

    Expedia

    Cozy & Classic in St. Charles, 5 Mins. to Main St!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    7

    Whether you’re visiting St. Charles for business, your favorite Lindenwood student, or one of St. Charles’ major festiva ...

    From $179 per night (USD)

    Expedia

    Details
  • UPSCALE HISTORIC MAIN ST*Huge Dining, Kitchen,Fenced BckYrd. PETS\/Handicap acces
    From $282 per night (USD)

    VRBO

    UPSCALE HISTORIC MAIN ST*Huge Dining, Kitchen,Fenced BckYrd. PETS\/Handicap acces

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    9

    This unique luxurious 1650 sqft open floor plan entire home is unlike any other home in the St. Charles area. Newly Remo ...

    From $282 per night (USD)

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    Details
  • Blair's House in O'Fallon 3 Bed 1.5 Bath Game Room
    From $159 per night (USD)

    Expedia

    Blair's House in O'Fallon 3 Bed 1.5 Bath Game Room

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Summary: Welcome to Blairs House in Central O'Fallon, where we ensure you have a cozy stay every day. 3 Bed 1.5 Bath Ho ...

    From $159 per night (USD)

    Expedia

    Details
  • Charming 2-Bedroom Apartment in Historic Frenchtown with Modern Amenities
    From $108 per night (USD)

    VRBO

    Charming 2-Bedroom Apartment in Historic Frenchtown with Modern Amenities

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    Discover Historic Frenchtown from our charming 2nd-floor apartment. With 2 beds, 1 bath, and modern comforts, elegance m ...

    From $108 per night (USD)

    VRBO

    Details
  • Deluxe renovated condo conveniently located to everything you'll need !
    From $180 per night (USD)

    VRBO

    Deluxe renovated condo conveniently located to everything you'll need !

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    6

    Contemporary design, completely renovated August 2023, appliances, floors, bathrooms, bedding, washer,dryer, front door ...

    From $180 per night (USD)

    VRBO

    Details
  • Charming Duplex on Main
    From $95 per night (USD)

    VRBO

    Charming Duplex on Main

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    This charming one bedroom, one bathroom duplex is the perfect haven for a weekend getaway, a family vacation, or a produ ...

    From $95 per night (USD)

    VRBO

    Details
  • Contemporary AND Cozy! Sleeps 6!
    From $150 per night (USD)

    Expedia

    Contemporary AND Cozy! Sleeps 6!

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Relax in this peaceful and stylish space. Updated with everything a guest will need to enjoy their stay - crisp linens, ...

    From $150 per night (USD)

    Expedia

    Details
  • Stunning 1890's Home - Sleeps 8!
    From $155 per night (USD)

    VRBO

    Stunning 1890's Home - Sleeps 8!

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    8

    This stunning home in St. Charles, MO, is an impressive single-family home. It offers 1,625 square feet of living space ...

    From $155 per night (USD)

    VRBO

    Details
  • Cozy Retreat Historic St. Peters
    From $220 per night (USD)

    VRBO

    Cozy Retreat Historic St. Peters

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Experience the allure of Old Town St. Peters in our charming 3-bedroom home. Nestled in a historic neighborhood, our coz ...

    From $220 per night (USD)

    VRBO

    Details
  • Duplex Hideaway in St. Charles, MO
    From $116 per night (USD)

    VRBO

    Duplex Hideaway in St. Charles, MO

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    This delightful one bedroom, one bathroom duplex is an ideal retreat for a weekend escape or a productive business journ ...

    From $116 per night (USD)

    VRBO

    Details
  • 3 bedroom home in ofallon
    From $181 per night (USD)

    Expedia

    3 bedroom home in ofallon

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    6

    This home is three bedrooms and 2 1/2 baths. It has a privacy fence in the backyard along with a pool and a deck that is ...

    From $181 per night (USD)

    Expedia

    Details
  • Stunning Basement Retreat at the Heart of St. Charles!
    From $89 per night (USD)

    VRBO

    Stunning Basement Retreat at the Heart of St. Charles!

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    3

    Welcome to our charming basement retreat. Ideal for couples or solo travelers seeking a peaceful haven, our tastefully f ...

    From $89 per night (USD)

    VRBO

    Details
  • Cozy 4bd\/1.5bth w\/game room, short walk to wedding venue. Golf nearby too!
    From $283 per night (USD)

    VRBO

    Cozy 4bd\/1.5bth w\/game room, short walk to wedding venue. Golf nearby too!

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    7

    The perfect combo of CLASSY meets FUN! From the arcade games, the children’s books/toys, to the comfy couches, fully equ ...

    From $283 per night (USD)

    VRBO

    Details
  • Peaceful Oasis in Historic St. Charles w\/ 4bd 2ba
    From $281 per night (USD)

    VRBO

    Peaceful Oasis in Historic St. Charles w\/ 4bd 2ba

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    8

    Located in the heart of Historic St. Charles, this VRBO house is a relaxing 4 bedroom, 2 bath house with sideyard deck a ...

    From $281 per night (USD)

    VRBO

    Details
  • Music House · Music House on Main Street at The Wine Garden
    From $130 per night (USD)

    Expedia

    Music House · Music House on Main Street at The Wine Garden

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    10

    This is a single family located at The Wine Garden! This house is perfect for lovers of music! While staying here you ca ...

    From $130 per night (USD)

    Expedia

    Details
  • Mansion 301 · 1st Capitol Mansion Boutique Hotel - Suite 301
    From $85 per night (USD)

    VRBO

    Mansion 301 · 1st Capitol Mansion Boutique Hotel - Suite 301

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    This unit is a hotel style unit that is located in the heart of downtown historic St. Charles. It's located right acros ...

    From $85 per night (USD)

    VRBO

    Details
  • 1st Capitol Mansion Boutique Hotel - Suite 201
    From $85 per night (USD)

    Expedia

    1st Capitol Mansion Boutique Hotel - Suite 201

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    This unit is a hotel style unit that is located in the heart of downtown historic St. Charles. It's located right acros ...

    From $85 per night (USD)

    Expedia

    Details
  • Mansion 302 · 1st Capital Mansion Boutique Hotel - Suite 302
    From $85 per night (USD)

    VRBO

    Mansion 302 · 1st Capital Mansion Boutique Hotel - Suite 302

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    First Capitol Mansion - The Louis Blanchette second floor The Mansion Make the most of your St. Charles experience with ...

    From $85 per night (USD)

    VRBO

    Details
  • The Olive House - Near Main Street- Fully rehabbed
    From $125 per night (USD)

    Expedia

    The Olive House - Near Main Street- Fully rehabbed

    Bedrooms:
    1
    Bathrooms:
    3
    Sleeps:
    8

    Beautifully rehabbed home with a brand new kitchen and bathroom. Wood floors have just been refinished and new flooring ...

    From $125 per night (USD)

    Expedia

    Details
  • 5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1
    From $84 per night (USD)

    VRBO

    5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    This Gem is fully renovated with everything you should need in the Historic District. The Katy Trail is just a 2 minute ...

    From $84 per night (USD)

    VRBO

    Details
  • Historic 5th Street House - Fully Rehabbed # 2
    From $89 per night (USD)

    Expedia

    Historic 5th Street House - Fully Rehabbed # 2

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    This Gem is fully renovated with everything you should need in the Historic District. The Katy Trail is just a 2 minute ...

    From $89 per night (USD)

    Expedia

    Details
  • Get away from it all
    From $203 per night (USD)

    VRBO

    Get away from it all

    Bedrooms:
    5
    Bathrooms:
    3
    Sleeps:
    6

    This is a beautiful home in the middle of 90+ acres of valleys, rolling hills, operational pumpkin and hops farm with lo ...

    From $203 per night (USD)

    VRBO

    Details
  • Quaint Bungalow near Main Street
    From $175 per night (USD)

    Expedia

    Quaint Bungalow near Main Street

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    8

    Visit historic downtown St. Charles with the comforts of this beautifully renovated farm house. This home has been renov ...

    From $175 per night (USD)

    Expedia

    Details
  • Charming Cottage on Main St. in Historic St. Charles! Jetted Tub, 2 Fireplaces!!
    From $213 per night (USD)

    VRBO

    Charming Cottage on Main St. in Historic St. Charles! Jetted Tub, 2 Fireplaces!!

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    8

    'The Main Street Guest House' is a charming vacation rental home located right in the center of Historic Main Street in ...

    From $213 per night (USD)

    VRBO

    Details
  • THE MADISON HOUSE #2 - HISTORIC AREA in ST CHARLES
    From $215 per night (USD)

    VRBO

    THE MADISON HOUSE #2 - HISTORIC AREA in ST CHARLES

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    7

    This townhouse is located in the Historic District of St. Charles MO. House is located a few blocks away from Main St, ...

    From $215 per night (USD)

    VRBO

    Details
  • Free Breakfast. Pool & Gym. Near Progress West Hospital!
    From $203 per night (USD)

    VRBO

    Free Breakfast. Pool & Gym. Near Progress West Hospital!

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    6

    Enjoy a wonderful trip to O'Fallon, courtesy of our 1 Bedroom Suite! It's close to the Busch Conservation Area, Progress ...

    From $203 per night (USD)

    VRBO

    Details
  • King Suite. Free Breakfast. Pool & Gym. Your Next Trip!
    From $204 per night (USD)

    VRBO

    King Suite. Free Breakfast. Pool & Gym. Your Next Trip!

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Enjoy a wonderful trip to O'Fallon, courtesy of our 1 Bedroom Suite! It's close to the Busch Conservation Area, Progress ...

    From $204 per night (USD)

    VRBO

    Details
  • Free Breakfast. Pool & Gym. Close to Progress West Hospital!
    From $203 per night (USD)

    VRBO

    Free Breakfast. Pool & Gym. Close to Progress West Hospital!

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Enjoy a wonderful trip to O'Fallon, courtesy of our 1 Bedroom Suite! It's close to the Busch Conservation Area, Progress ...

    From $203 per night (USD)

    VRBO

    Details
  • Minutes from Main Street - Updated House w\/ 4 Patios, Private Parking & Trolley
    From $198 per night (USD)

    VRBO

    Minutes from Main Street - Updated House w\/ 4 Patios, Private Parking & Trolley

    Bedrooms:
    1
    Bathrooms:
    3
    Sleeps:
    8

    Located in the heart of Frenchtown, is this beautifully updated home that sleeps 8. This is a must see!!! From the custo ...

    From $198 per night (USD)

    VRBO

    Details
  • Spacious and Comfortable Home in Saint Peters
    From $246 per night (USD)

    VRBO

    Spacious and Comfortable Home in Saint Peters

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    8

    Elegant and spacious home in Saint Peters with plenty of room for family and children. Stay here if you're looking for a ...

    From $246 per night (USD)

    VRBO

    Details
  • The Estate at Sunflower Hill Farm
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    VRBO

    The Estate at Sunflower Hill Farm

    Bedrooms:
    5
    Bathrooms:
    5
    Sleeps:
    8

    The Estate at Sunflower Hill Farm is a 5-Bedroom Luxury Farmhouse on 24 Acres of land. The property is a hidden gem in M ...

    Click For Pricing

    VRBO

    Details
  • Luxurious couples retreat just steps from Historic Main Street in St. Charles!
    From $208 per night (USD)

    VRBO

    Luxurious couples retreat just steps from Historic Main Street in St. Charles!

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    3

    The Lewis & Clark Guest House is a historic cottage that has been thoughtfully remodeled into a luxurious retreat while ...

    From $208 per night (USD)

    VRBO

    Details
  • Private Vineyard
    From $249 per night (USD)

    VRBO

    Private Vineyard

    Bedrooms:
    2
    Bathrooms:
    1
    Sleeps:
    3

    Have your privacy to a home of your own with backyard firepit overlooking a vineyard. Less than .5 miles from downtown ...

    From $249 per night (USD)

    VRBO

    Details
  • Beautifully Renovated home in the heart of Historic Saint Charles
    From $75 per night (USD)

    VRBO

    Beautifully Renovated home in the heart of Historic Saint Charles

    Bedrooms:
    1
    Bathrooms:
    3
    Sleeps:
    6

    Fall for this quaint three bedroom house in the heart of downtown Saint Charles. The home is walking distance to the Mai ...

    From $75 per night (USD)

    VRBO

    Details
  • Wonderful Oak Log Home on the Mississippi River
    From $250 per night (USD)

    VRBO

    Wonderful Oak Log Home on the Mississippi River

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    7

    A piece of Heaven! Wonderful 2000 sq. ft., 1.5 story oak, log home overlooking (& direct access to) the Mississippi R ...

    From $250 per night (USD)

    VRBO

    Details
  • Scenic and private retreat in Missouri wine country
    From $525 per night (USD)

    VRBO

    Scenic and private retreat in Missouri wine country

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Just 35 miles from St. Louis and 2 miles from the charming town of Augusta, MO. Our 140 acres are nestled on a hillside ...

    From $525 per night (USD)

    VRBO

    Details
  • 1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!
    From $165 per night (USD)

    Expedia

    1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    'The Riverfront Guest House' located at #422 Rear S. Main Street centrally located in the historic district of St. Charl ...

    From $165 per night (USD)

    Expedia

    Details
  • Cozy Wine Country Home [ Lodging only ... this is not an event venue ]
    From $216 per night (USD)

    VRBO

    Cozy Wine Country Home [ Lodging only ... this is not an event venue ]

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    5

    Guests are sure to enjoy a memorable stay in this fully furnished, 3 bedroom/2 bath ranch home property.  The main/maste ...

    From $216 per night (USD)

    VRBO

    Details
  • 1790's Renovated Barn, Main Street St. Charles, Hot Tub in private backyard!
    From $208 per night (USD)

    Expedia

    1790's Renovated Barn, Main Street St. Charles, Hot Tub in private backyard!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    The Red Barn Guest House is a beautifully remodeled home with amazing details that makes this vacation rental truly uniq ...

    From $208 per night (USD)

    Expedia

    Details
  • The St. Charles Guest House, lovely historic home, fun for families and groups
    From $213 per night (USD)

    VRBO

    The St. Charles Guest House, lovely historic home, fun for families and groups

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    "The St. Charles Guest House" is a beautifully renovated and decorated home in the heart of Historic St. Charles, MO. Th ...

    From $213 per night (USD)

    VRBO

    Details
  • 1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
    From $218 per night (USD)

    Expedia

    1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    7

    The Old Town Guest House is an upscale vacation home originally built in 1870 and beautifully renovated with tasteful an ...

    From $218 per night (USD)

    Expedia

    Details