Isle of Palms South Rentals
From $343 per night (USD)VRBO
Comfy Mayo Retreat; Heated Pool, Close to Beach
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 8
Palms Bungalow is a 3 bedroom 2 bath pool home, only 1 mile from Mayo Clinic and 3 miles from Jacksonville Beach. This o ...
From $343 per night (USD)VRBO
From $350 per night (USD)Expedia
Modern Townhouse minutes from Mayo Clinic UNF & Beach
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 9
Beautiful townhouse located in the sought after San Pablo area. Fully furnished 3 Bedroom, 2.5 bathroom & car garage. Th ...
From $350 per night (USD)Expedia
From $252 per night (USD)VRBO
Light Grey Getaway under 2 miles to mayo, 4 miles to the beach
- Bedrooms:
- 3
- Bathrooms:
- 4
- Sleeps:
- 8
We believe that you will feel right at home in our bungalow. The backyard will feel like an oasis with a comfortable con ...
From $252 per night (USD)VRBO
From $368 per night (USD)Expedia
Your Home Away From Home and 2 miles from The Mayo Clinic and Snowbirds welcomed
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 6
3 bedroom 2 bath home newly renovated located in a quiet neighborhood 2 miles from Mayo Clinic and a few minutes from th ...
From $368 per night (USD)Expedia
From $374 per night (USD)VRBO
Mayo Clinc 1mile from Intercoastal waterfront home w/pool and Breathtaking Views
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 8
Enjoy amazing water views from EVERY single room in this newly renovated ICW pool home (renovated in March 2016 / Pool N ...
From $374 per night (USD)VRBO
From $328 per night (USD)Expedia
Fancy private pool home in Jax beach
- Bedrooms:
- 2
- Bathrooms:
- 4
- Sleeps:
- 10
Have fun with the whole family at this stylish place. This house offers a relaxing feel for family and friends vacation ...
From $328 per night (USD)Expedia
From $400 per night (USD)VRBO
Tranquility by Mayo w/ Heated Pool Mins to Beach
- Bedrooms:
- 2
- Bathrooms:
- 4
- Sleeps:
- 8
Experience tranquility at Osprey’s Rest, a pet-friendly beach house in Jacksonville Beach’s serene Isle of Palms neighbo ...
From $400 per night (USD)VRBO
From $229 per night (USD)Expedia
The Retreat close to Mayo Clinic!
- Bedrooms:
- 1
- Bathrooms:
- 3
- Sleeps:
- 6
Book with confidence with an experienced host! The Retreat is a fully renovated 3 bedroom/2 bathroom house. Guests are ...
From $229 per night (USD)Expedia
From $272 per night (USD)VRBO
NEW- The Cove at San Pablo- Across from the Mayo Clinic
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 6
**NEW** Welcome to the Cove at San Pablo! Come visit Jax and relax in our newly renovated and fully furnished with 3 bed ...
From $272 per night (USD)VRBO
From $269 per night (USD)Expedia
Big Wheelchair Accessible Home Close to Beach/Mayo with Zen Den and Fenced Yard
- Bedrooms:
- 3
- Bathrooms:
- 4
- Sleeps:
- 10
*New to VRBO* Welcome to “The Cottage” a recently remodeled spacious and accessible brick ranch home in the heart of Ja ...
From $269 per night (USD)Expedia
From $398 per night (USD)VRBO
Manatee House: Private Marsh View Retreat - 1 Mile to Mayo, 5 Miles to Beaches
- Bedrooms:
- 3
- Bathrooms:
- 4
- Sleeps:
- 12
You will love this beautiful and comfortable large marsh view home. Perfect location in a quiet neighborhood within walk ...
From $398 per night (USD)VRBO
From $207 per night (USD)VRBO
The Lily House- Flexible Lease Terms, Hospitals and Beaches
- Bedrooms:
- 3
- Bathrooms:
- 3
- Sleeps:
- 8
Come enjoy the sunshine state and plenty of natural light throughout this brand new, fully furnished townhome- minutes t ...
From $207 per night (USD)VRBO
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Quiet home on a cul-de-sac with screened patio, W/D, & central AC
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 6
By the Beach - Main Our calendar is updated in real-time & our nightly rates are accurately displayed. Simply enter you ...
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From $224 per night (USD)VRBO
Pablo Pointe- Single Family Home directly across from the Mayo Clinic
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 6
We invite you to stay at Pablo Pointe, our new fully renovated family ranch home. Ideal for families and/or patients vis ...
From $224 per night (USD)VRBO
From $344 per night (USD)VRBO
Tres Palmas!Renovated Pool Home Near Mayo & Beach!
- Bedrooms:
- 2
- Bathrooms:
- 4
- Sleeps:
- 6
Comfort, location, and calm! From the moment you arrive at Las Palmas you will feel that the home has been designed with ...
From $344 per night (USD)VRBO
From $233 per night (USD)Expedia
Charming 3-bedroom house in Jacksonville
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 6
Your home away from home in Jacksonville with 3 bedrooms, including 2 king beds and 1 twin bed. This amazing house offer ...
From $233 per night (USD)Expedia
From $403 per night (USD)VRBO
Beautiful 3 bedroom, 2 bathroom Beach Bungalow in Jacksonville Beach!
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 8
Make yourself at home in this charming 3-bedroom, 2 bathroom Jacksonville Beach retreat. With a king bed, full bed, and ...
From $403 per night (USD)VRBO
From $254 per night (USD)VRBO
1 Min to Mayo Clinic, 5 to Beach Luxury Suite with 2 King Beds
- Bedrooms:
- 2
- Bathrooms:
- 2
- Sleeps:
- 6
MAYO CLINIC - 1 MIN AWAY | 5 MIN TO BEACH 2BR/2BA retreat steps from Mayo Clinic! 5 MIN to the beach & 1 MIN to dinin ...
From $254 per night (USD)VRBO
From $405 per night (USD)VRBO
5 min to Mayo—luxury, comfort & care designed for patients & caregivers.
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 8
Whether you're traveling as a patient or simply seeking a peaceful getaway, Rest and Wellness by Doctor offers comfort, ...
From $405 per night (USD)VRBO
From $297 per night (USD)Expedia
Saltwater Pool I Firepits I Large Fenced Backyard I 4 Miles to Beach
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 6
Welcome to the Turquoise Oasis! This charming 3-bedroom, 2.5-bath home features a first-floor primary suite, a sparkling ...
From $297 per night (USD)Expedia
From $444 per night (USD)VRBO
SMV Palm Escape Retreat nr Mayo
- Bedrooms:
- 2
- Bathrooms:
- 4
- Sleeps:
- 10
Unwind by the sparkling private pool, practice your swing on the putting green, or sip a drink at the outdoor bar and gr ...
From $444 per night (USD)VRBO
From $245 per night (USD)Expedia
Pet-Friendly Rental, Pool Table, 7 Min to Mayo Clinic!
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 6
Welcome to Your Jacksonville Beachside Retreat! Discover the perfect blend of comfort, convenience, and vibrant fun in o ...
From $245 per night (USD)Expedia
Click For PricingVRBO
Dog-friendly waterfront home with private dock, boat lift, pool and spa
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 8
Reel Relaxed Our calendar is updated in real-time & our nightly rates are accurately displayed. Simply enter your desir ...
Click For PricingVRBO
From $536 per night (USD)Expedia
Pool home on the Water near Mayo
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 6
Coastal Canal Retreat | Pool • 3BR Welcome to your serene escape on the water! This home is nestled on a quiet canal jus ...
From $536 per night (USD)Expedia
From $280 per night (USD)VRBO
Canal-Front Retreat 4 Mi to Jacksonville Beach!
- Bedrooms:
- 3
- Bathrooms:
- 4
- Sleeps:
- 8
2 Mi to Mayo Clinic | BBQ-Ready Patio | Private Yard w/ Water Views Sunshine and serenity await at this Jacksonville va ...
From $280 per night (USD)VRBO
From $431 per night (USD)VRBO
Fox Hollow Peaceful Fruit Forest Getaway. Four bedrooms, two bathrooms
- Bedrooms:
- 2
- Bathrooms:
- 4
- Sleeps:
- 8
Welcome to Fox Hollow—a serene single-level retreat tucked away in a peaceful neighborhood. Designed with comfort and st ...
From $431 per night (USD)VRBO
From $182 per night (USD)VRBO
ODA Tiny Home
- Bedrooms:
- 1
- Bathrooms:
- 1
- Sleeps:
- 3
Welcome to ODA, your charming and cozy guesthouse retreat. This thoughtfully designed studio combines comfort, style, an ...
From $182 per night (USD)VRBO
From $421 per night (USD)Expedia
Northeast Florida Retreat
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 8
Elegant Waterfront Haven | Dock, Boat Lift, Pool | Dog-Friendly Welcome to Coastal Serenity—a stylish single-level retr ...
From $421 per night (USD)Expedia
From $182 per night (USD)VRBO
Quiet Coastal Home w/ Patio Near Beaches
- Bedrooms:
- 2
- Bathrooms:
- 3
- Sleeps:
- 6
Quiet Coastal Home w/ Patio Near Beaches Sunny Cul-de-Sac Retreat Near Jacksonville Beaches Nestled on a quiet cul-de- ...
From $182 per night (USD)VRBO
From $156 per night (USD)Expedia
Modern In-Law Suite Near Jax Beaches & Mayo
- Bedrooms:
- 1
- Bathrooms:
- 2
- Sleeps:
- 4
Modern In-Law Suite Near Jax Beaches & Mayo Modern In-Law Suite Near Beaches & Mayo Clinic Relax in comfort at this pr ...
From $156 per night (USD)Expedia