La Mesa, California Vacation Rentals. Book Beach Rentals, Lake Houses, Condos, Cabins, Villas, and Homes in La Mesa, California on RentalSaver.com!

La Mesa Rentals

From $254 per night (USD)
VRBO
Quite Peaceful Mountain Retreat
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
above the valley below, with an exquisite colorful evening sunsets in the valley. 2 units on the property with separa ...
From $254 per night (USD)
VRBO
From $393 per night (USD)
Expedia
Palm Cottage San Diego
Bedrooms:
1
Bathrooms:
2
Sleeps:
5
Charming Craftsman Cottage in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully r ...
From $393 per night (USD)
Expedia
From $564 per night (USD)
VRBO
Quiet peaceful getaway
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Located at the toe of mt helix surrounded by mountains n trees nice cool breeze constantly flowing, Close freeway acce ...
From $564 per night (USD)
VRBO
From $167 per night (USD)
VRBO
Your Home Away From Home! 12 min. to SanDiego! Kids & Pets OK! Kitch/wifi/yard/
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
Nicely furnished and conveniently located home with no attached walls to other units. You, your family and fur buddies ...
From $167 per night (USD)
VRBO
From $334 per night (USD)
VRBO
Travel Writer's Pad
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
Hello, Bonjour, Hola, Ciao, Ni Hao! Welcome to Travel Writer's Pad. It’s a pleasure to have you as my guest. For the ...
From $334 per night (USD)
VRBO
From $423 per night (USD)
Expedia
***Romantic View Home Centrally Located in Windsor Hills, La Mesa***
Bedrooms:
2
Bathrooms:
3
Sleeps:
7
NOTE: VRBO Quote is for the Main House 2B/2B! Beautifully remodeled and newly furnished home in lovely Windsor Hills, c ...
From $423 per night (USD)
Expedia
From $142 per night (USD)
VRBO
Zen Retreat San Diego
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Enjoy the feeling of a cozy Zen Retreat on lovely Mt Helix in San Diego county. Mt. Helix is a short 15 minutes from t ...
From $142 per night (USD)
VRBO
From $631 per night (USD)
Expedia
The Hidden Treasure Estate
Bedrooms:
2
Bathrooms:
4
Sleeps:
14
Welcome to your home away from home in the heart of La Mesa! This pristine cozy hideaway has everything you need for a f ...
From $631 per night (USD)
Expedia
From $162 per night (USD)
VRBO
Your Home Away From Home! 10 Minutes to San Diego! Wifi, Kitchen, PetsOK, 1br.
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
There are two cute, fun, remodeled, nicely furnished and conveniently located duplexes. They are attached with one comm ...
From $162 per night (USD)
VRBO
From $493 per night (USD)
Expedia
Charming Family-Friendly La Mesa - Hot Tub
Bedrooms:
2
Bathrooms:
4
Sleeps:
9
Live like a local in this charming, family-friendly La Mesa home. Enjoy four comfortable bedrooms, a spacious living roo ...
From $493 per night (USD)
Expedia
From $289 per night (USD)
VRBO
3 Bedroom House - Fire Pit Table, BBQ - 10 Guests
Bedrooms:
1
Bathrooms:
3
Sleeps:
10
Capture the essence of San Diego in our 3 bedroom house hosted by Ethos Vacation Homes. The peaceful property features e ...
From $289 per night (USD)
VRBO
From $296 per night (USD)
Expedia
La Mesa Townhome: 15 Mi to San Diego!
Bedrooms:
2
Bathrooms:
2
Sleeps:
5
See what SoCal is all about and let the West Coast prove that it’s really the best coast when you book your stay at this ...
From $296 per night (USD)
Expedia
From $158 per night (USD)
VRBO
Affordable Escape #4,kitch,yard, pets ok, wifi, 10 min to San Diego
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Cute, fun, newly remodeled, nicely furnished and conveniently located home. Full Kitchen and separate bedroom with a ki ...
From $158 per night (USD)
VRBO
From $236 per night (USD)
Expedia
2 Bed 2 Bath 15-20 Minutes to all the Best of San Diego!
Bedrooms:
2
Bathrooms:
2
Sleeps:
5
You will have complete access to the entire 2 bed 2 bath home. We benefit from ocean breezes on most days of the year b ...
From $236 per night (USD)
Expedia
From $193 per night (USD)
VRBO
New Basement Apartment
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Brand new 1 bedroom 1 bath basement apartment. Easy freeway access only 15 minutes to Zoo, SeaWorld, Airport, Downtown, ...
From $193 per night (USD)
VRBO
From $140 per night (USD)
Expedia
Hidden King Suite with Garden, Parking - 4 Guest
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful prope ...
From $140 per night (USD)
Expedia
From $332 per night (USD)
VRBO
Luxury Guest-residence in a Beautiful garden just 15min from San Diego & Beaches
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Casita DOLCEVITA is a totally independent, lovely, and cozy apartment, with direct and exclusive access and use to the p ...
From $332 per night (USD)
VRBO
From $173 per night (USD)
VRBO
Quiet, private studio getaway in a nice neighborhood
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Located at the top of the street with a wonderful breeze. A private, cozy studio connected to the main house. Five minut ...
From $173 per night (USD)
VRBO
Click For Pricing
VRBO
Tranquil 2 Bedroom w/ Fenced Yard...Walking Distance to La Mesa Village
Bedrooms:
0
Bathrooms:
2
Sleeps:
5
Tranquil 2 bedroom 1 bath home Nestled in a quiet La Mesa neighborhood, located on multi unit residence on .25 of an acr ...
Click For Pricing
VRBO
From $190 per night (USD)
VRBO
Sweet roomy studio with patio and grassy area for your fur buddy!
Bedrooms:
1
Bathrooms:
0
Sleeps:
0
The studio is cozy, with a queen size bed, two recliners and a large outdoor space with a full size grill and patio seat ...
From $190 per night (USD)
VRBO
From $436 per night (USD)
VRBO
Family Pool Retreat + Gym, Fire Pits, Views (Sleeps 9
Bedrooms:
2
Bathrooms:
3
Sleeps:
9
Hey there, awesome families looking for fun in San Diego! Imagine this: You wake up in a comfy house perched on a hill, ...
From $436 per night (USD)
VRBO
From $201 per night (USD)
Expedia
Cottage in the Garden. New! Modern!
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
COTTAGE IN THE GARDEN - New! Modern! Find beauty, privacy and comfort in this special home in one of San Diego's most de ...
From $201 per night (USD)
Expedia
From $535 per night (USD)
VRBO
Entertainers Dream Pool Home
Bedrooms:
2
Bathrooms:
3
Sleeps:
15
The Lemon Ave Pool Home! Ready for your enjoyment, this home has EVERYTHING you need to enjoy a large get-together with ...
From $535 per night (USD)
VRBO
From $121 per night (USD)
Expedia
Charming, private, pet friendly cottage close to all that San Diego has to offer
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Unwind in this elegant bungalow with a history of nurturing. The large brick oven in your courtyard was used to feed sol ...
From $121 per night (USD)
Expedia
From $95 per night (USD)
VRBO
Cozy & Comfortable Two Story Townhouse
Bedrooms:
0
Bathrooms:
2
Sleeps:
4
This home is in a very quiet setting, a large front window allows plenty of light flow. Lots of trees and vegetation. Ea ...
From $95 per night (USD)
VRBO
From $600 per night (USD)
VRBO
Designer 4 BR La Mesa Home w/ Yard and BBQ
Bedrooms:
3
Bathrooms:
4
Sleeps:
9
Summary: Relax and enjoy this spacious and elegant La Mesa home! It's recently remodeled with an open kitchen, a modern ...
From $600 per night (USD)
VRBO
From $139 per night (USD)
VRBO
Welcoming bungalow with den, ideal for longer stays, near everything!
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
Be at home in this mid-century Craftsman cottage - whip up a great meal in your fully stocked kitchen, snooze in plush c ...
From $139 per night (USD)
VRBO
From $110 per night (USD)
Expedia
Chic, yet playful boho bungalow near everything!
Bedrooms:
1
Bathrooms:
1
Sleeps:
3
This cozy (yup, 'cozy' is a euphemism for small) bungalow has a snazzy vibe. It is flooded with natural light that highl ...
From $110 per night (USD)
Expedia
From $609 per night (USD)
VRBO
5br Home with Pool, Hot Tub, BBQ, Putting green
Bedrooms:
3
Bathrooms:
4
Sleeps:
10
Summary: Welcome to your La Mesa oasis! This stunning house features a private pool, hot tub, and a game room, perfect ...
From $609 per night (USD)
VRBO
From $576 per night (USD)
Expedia
The Sky Lounge
Bedrooms:
3
Bathrooms:
5
Sleeps:
16
Your private slice of paradise awaits! Spend sunny days by the pool, unwind in the hot tub, sip drinks at the tiki loung ...
From $576 per night (USD)
Expedia
From $312 per night (USD)
VRBO
Single Level Home by La Mesa Village, Outdoor Deck + 🔥Pit, Fenced Yard for Pets
Bedrooms:
2
Bathrooms:
4
Sleeps:
10
Welcome to this beautifully remodeled single-story home in La Mesa located in a charming neighborhood with plenty of roo ...
From $312 per night (USD)
VRBO
From $268 per night (USD)
Expedia
Sunny San Diego La Mesa Charming 2 bd /1 bth Home, Beaches, Sea World, Zoo,
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
Enjoy location and sunshine most of the time. Plenty of parking and close to beaches, tourist sites, golf, San Diego Sta ...
From $268 per night (USD)
Expedia
From $515 per night (USD)
VRBO
Palm & Peace Retreat
Bedrooms:
2
Bathrooms:
5
Sleeps:
12
This La Mesa gem blends boho vibes with tropical flair. Enjoy a peaceful Zen garden, saltwater pool, and relaxing jacuzz ...
From $515 per night (USD)
VRBO
From $759 per night (USD)
Expedia
La Mesa 5BR | Pickleball Court + Hot Tub
Bedrooms:
2
Bathrooms:
5
Sleeps:
16
Bring the whole group together for an unforgettable stay at this newly remodeled La Mesa retreat, where fun, comfort, an ...
From $759 per night (USD)
Expedia
From $865 per night (USD)
VRBO
Luxury Home! Heated Pool+Spa+Firepit
Bedrooms:
4
Bathrooms:
4
Sleeps:
10
Escape from the everyday & enjoy a luxurious vacation in this fully renovated (inside and out) 4-bedroom/3.5 bath home w ...
From $865 per night (USD)
VRBO
From $248 per night (USD)
Expedia
Designer Poolside La Mesa Retreat w/ BBQ & Yard
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Summary: Welcome to your La Mesa retreat! This charming guesthouse offers a bright and airy one-bedroom apartment with ...
From $248 per night (USD)
Expedia
From $180 per night (USD)
VRBO
Serenity Garden Studio [33% long term, 10% short term discount!]
Bedrooms:
1
Bathrooms:
0
Sleeps:
2
If you enjoy your peace of mind and privacy, and if you like the Mediterranean like climate, fruit orchards and flower g ...
From $180 per night (USD)
VRBO
From $254 per night (USD)
VRBO
Beautiful upscale condo with many great amenities!
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Large living room with leather sofa and 70" TV, a full width balcony with view of the manicured property and pool area. ...
From $254 per night (USD)
VRBO
From $261 per night (USD)
VRBO
Family Fun! Stylish Escape + Game Garage + Ping Pong + Big Yard + Free Parking
Bedrooms:
2
Bathrooms:
3
Sleeps:
7
Our space has the perfect blend of a vintage feel with a modern touch. With contemporary design & vibrant artwork it emb ...
From $261 per night (USD)
VRBO
From $341 per night (USD)
Expedia
Cozy Mid-Century Charmer - Huge Backyard - Firepit
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Welcome to our renovated mid-century home in La Mesa! Perfect for family or friend getaways, this quiet retreat offers a ...
From $341 per night (USD)
Expedia
From $284 per night (USD)
VRBO
*Stunning Waterfall & Glittering Pool**Spacious Home**Perfect 4 Family Reunions*
Bedrooms:
4
Bathrooms:
4
Sleeps:
14
**The calming, tropical aura of San Diego is found in this spacious four-bedroom, four bath fully furnished Corporate Re ...
From $284 per night (USD)
VRBO
From $224 per night (USD)
Expedia
Downtown La Mesa gem
Bedrooms:
2
Bathrooms:
1
Sleeps:
8
Your family/group will be close to everything when you stay at this centrally-located place. Newly renovated La Mesa ret ...
From $224 per night (USD)
Expedia
From $306 per night (USD)
VRBO
An elegant, fully furnished guest house for 2-4 guest in San Diego
Bedrooms:
1
Bathrooms:
2
Sleeps:
5
Enjoy the ultimate in convenience with this fully furnished unit, in Mt. Helix, La Mesa. Perfectly located within walkin ...
From $306 per night (USD)
VRBO
From $258 per night (USD)
VRBO
Your own Suburban Oasis!
Bedrooms:
1
Bathrooms:
1
Sleeps:
3
About this space Enjoy a stylish experience at this centrally-located place. Swimming pool, bbq, pool table, comfort lou ...
From $258 per night (USD)
VRBO
From $851 per night (USD)
VRBO
Family Fun Mountain Villa in San Diego Pool/Jacuzzi, Water-slide, PickleBall
Bedrooms:
4
Bathrooms:
5
Sleeps:
12
Enjoy your own private resort-style retreat in San Diego, designed for families and group getaways. This spacious 5-bedr ...
From $851 per night (USD)
VRBO
From $154 per night (USD)
VRBO
Modern Guesthouse Studio✸2-Level Fenced Patio✸Near La Mesa Village✸Pets Welcome
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Welcome to our clean and stylish studio within a quiet and charming La Mesa neighborhood! The guesthouse is a fully deta ...
From $154 per night (USD)
VRBO
From $569 per night (USD)
VRBO
Family Retreat - game room & basketball court in La Mesa
Bedrooms:
2
Bathrooms:
3
Sleeps:
12
Indoor outdoor living in San Diego at its finest. Entertain and dine outdoors by the grill. There is a game room, basket ...
From $569 per night (USD)
VRBO
From $128 per night (USD)
Expedia
Charming studio in delightful La Mesa with WiFi, AC and Deck
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Your cozy getaway awaits in La Mesa at this adorable studio. This charming space features a comfortable king bed, a mode ...
From $128 per night (USD)
Expedia
From $216 per night (USD)
VRBO
Beautiful, spacious and bright
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Bright and spacious 1 bed very private apartment,This beautifully designed apartment features an open floor plan, modern ...
From $216 per night (USD)
VRBO
From $353 per night (USD)
Expedia
Enjoy Stylish Heaven in La Mesa Steps to Everything, Near SSU
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
Welcome to my home! I'm renting my beautiful house out while I’m gone on travels and hope you enjoy it as much as I do! ...
From $353 per night (USD)
Expedia
From $248 per night (USD)
VRBO
Centrally Located Cottage Near Lake Trails Shops
Bedrooms:
1
Bathrooms:
2
Sleeps:
5
Centrally located 2 bedroom 1 bathroom San Diego cottage! Easy access to SHOPPING, FOOD, HOSPITALS, LAKES, HIKING TRAILS ...
From $248 per night (USD)
VRBO
From $280 per night (USD)
VRBO
Artistic Oasis. Charming 3-bedroom house in La Mesa with AC, WiFi, washer/dryer
Bedrooms:
1
Bathrooms:
3
Sleeps:
6
Make yourself at home in this 3-bedroom La Mesa retreat. This amazing house features a king bed, queen bed, and twin bed ...
From $280 per night (USD)
VRBO
From $359 per night (USD)
VRBO
Sunnyside Resort Spa, Beach, Zoo, Arcade
Bedrooms:
2
Bathrooms:
3
Sleeps:
10
This enchanting villa in La Mesa is a serene retreat for guests seeking a peaceful getaway. With 3 cozy bedrooms includi ...
From $359 per night (USD)
VRBO
From $238 per night (USD)
Expedia
Charming 2-bedroom house with WiFi and AC in tranquil La Mesa
Bedrooms:
2
Bathrooms:
2
Sleeps:
5
This 2-bedroom house (duplex) in La Mesa is perfect for your escape to a tranquil retreat. With a king bed and a twin be ...
From $238 per night (USD)
Expedia
From $468 per night (USD)
VRBO
Modern SD Escape: SDSU/Downtown <10 Min, GameRoom, Fire Pit, Easy Freeway Access
Bedrooms:
2
Bathrooms:
3
Sleeps:
7
This Vrbo is the perfect home base for small groups/families visiting America's Coolest City! Just a short drive away f ...
From $468 per night (USD)
VRBO
From $509 per night (USD)
Expedia
Girls & Family Trip+Pool+beauty bar, San Diego
Bedrooms:
2
Bathrooms:
4
Sleeps:
10
Welcome to Le Palmier (The Palm), the remodeled home is perfect for a girls or family trip to San Diego! Escape to a won ...
From $509 per night (USD)
Expedia
From $752 per night (USD)
VRBO
Mt. Nebo Oasis in La Mesa w/ Wraparound Deck
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Outdoor Dining Area | 10 Mi to Gaslamp Quarter | Quiet & Private When you stay at this 3-bedroom, 2-bath vacation renta ...
From $752 per night (USD)
VRBO
From $734 per night (USD)
VRBO
Amazing Views + massive pool! Total Oasis
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Stay at this charming 3-bedroom, 2-bath vacation rental in La Mesa and experience the best of both worlds. Spend your da ...
From $734 per night (USD)
VRBO
From $499 per night (USD)
VRBO
25% off, Private Pool•Hot Tub•BBQ•Chef’s Kitchen•CentralSD•4 mins to SDSU
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
Unwind at this stylish home that sleeps 6, featuring a 👩‍🍳 chef’s kitchen, smart TVs, high-speed Wi-Fi, and a modern b ...
From $499 per night (USD)
VRBO
From $171 per night (USD)
Expedia
La Mesa Hillside Studio | Private Patio + Fast Wifi
Bedrooms:
1
Bathrooms:
1
Sleeps:
3
Centrally located in a quiet neighborhood close to the best open parks and beaches San Diego has to offer, book your esc ...
From $171 per night (USD)
Expedia
From $222 per night (USD)
VRBO
Near trolley. NEW charming 1-bedroom home in Fletcher hills, La Mesa.
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Your San Diego adventure begins in this newly built, stylish, 1 bedroom. Just 20 min from the beach, SeaWorld, 7 min ...
From $222 per night (USD)
VRBO
From $628 per night (USD)
Expedia
Golden Hour Bliss: Pool, Hot Tub & Firepit
Bedrooms:
3
Bathrooms:
4
Sleeps:
10
Perched atop the hills of La Mesa, this spacious retreat offers the perfect blend of relaxation, comfort, and convenienc ...
From $628 per night (USD)
Expedia
From $229 per night (USD)
VRBO
Welcome to SD Cozy Home - B
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Welcome to SD Cozy Home. This Brand New Modern ADU was just created with an Oasis Style. Immerse yourself in our state o ...
From $229 per night (USD)
VRBO
From $228 per night (USD)
Expedia
Welcome to SD Cozy Home - A
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Welcome to SD Cozy Home. This Brand New Modern ADU was just created with an Oasis Style. Immerse yourself in our state o ...
From $228 per night (USD)
Expedia
From $403 per night (USD)
VRBO
Welcome SD Cozy Suits A & B Together
Bedrooms:
2
Bathrooms:
2
Sleeps:
8
Welcome to SD Cozy Suits. This Brand New Modern ADU was just created with an Oasis Style. Immerse yourself in our state ...
From $403 per night (USD)
VRBO
From $627 per night (USD)
Expedia
Serene 4BR La Mesa Hideaway
Bedrooms:
2
Bathrooms:
4
Sleeps:
10
Summary: Forget your worries in this spacious and serene four bedroom space with a pool, backyard playground, BBQ, and ...
From $627 per night (USD)
Expedia
From $151 per night (USD)
VRBO
Mt. Helix Casita 10 minutes to SDSU, 20 minutes to beach
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Our newly renovated cottage is serene and comfy. Enjoy the natural surroundings while remaining within reach of all San ...
From $151 per night (USD)
VRBO
From $442 per night (USD)
Expedia
Techie Family Stay - Heart of San Diego
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
The perfect stay for your next family vacation. Centrally located between the cozy charm of La Mesa and the excitement o ...
From $442 per night (USD)
Expedia
From $342 per night (USD)
VRBO
Lime Light La Mesa New 4BR 3BA, Group Friendly
Bedrooms:
3
Bathrooms:
1
Sleeps:
13
Brand new 4 bed/3 bath vacation home comfortably sleeps up to 13 guests! Enjoy a wonderful outdoor area featuring a cozy ...
From $342 per night (USD)
VRBO
From $545 per night (USD)
Expedia
La Mesa Family Retreat - 20 minutes to Beaches & More!
Bedrooms:
3
Bathrooms:
3
Sleeps:
11
Welcome to your perfect La Mesa getaway! This spacious three bedroom, three bath home is designed for families and group ...
From $545 per night (USD)
Expedia
From $426 per night (USD)
VRBO
Spacious King Bed Ranch Style, Prime Area, 4BR/2BTH
Bedrooms:
2
Bathrooms:
4
Sleeps:
16
Click the Save button in the top-right corner to easily find us again before your dates are booked. Welcome to our fami ...
From $426 per night (USD)
VRBO
From $169 per night (USD)
VRBO
Stylish Terracotta Casita •1 Bedroom and bath • AC •WiFi in delightful La Mesa
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Welcome to Terracotta Casita! Enjoy a stylish and comfortable stay in our brand-new, centrally located apartment—just 9 ...
From $169 per night (USD)
VRBO
From $305 per night (USD)
VRBO
25% off, Chic Casita • Hot tub • BBQ • 4 min to SDSU
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Welcome to Boho Bliss 🌿 a newly built 1-bedroom guest house designed for comfort, style, and total relaxation. Soak in ...
From $305 per night (USD)
VRBO
From $856 per night (USD)
Expedia
Central SD• Luxury Home+Casita, Pool•Hot tub•BBQ•Sleeps10
Bedrooms:
2
Bathrooms:
3
Sleeps:
10
Welcome to Boho Escape, your private San Diego compound featuring two fully detached, single-level homes: Boho Tides (Un ...
From $856 per night (USD)
Expedia
From $469 per night (USD)
VRBO
San Diego Retreat ·Jacuzzi + Billiards +Sleeps 12!
Bedrooms:
4
Bathrooms:
4
Sleeps:
12
New hot tub! Lot`s of space! This is the perfect home base for your San Diego getaway. Relax in this gorgeous home whil ...
From $469 per night (USD)
VRBO
From $267 per night (USD)
Expedia
Lux 3BR w/ King Beds & Fire Pit
Bedrooms:
3
Bathrooms:
3
Sleeps:
8
Escape to our brand-new, luxury 3-bedroom La Mesa home, minutes from San Diego’s top attractions. Perfect for families o ...
From $267 per night (USD)
Expedia
From $286 per night (USD)
VRBO
Lake Murray 3BR Retreat with AC and Skylight
Bedrooms:
1
Bathrooms:
3
Sleeps:
5
Unwind in this stylish, newly remodeled coastal-themed guesthouse just minutes on foot from Lake Murray, shops, coffee, ...
From $286 per night (USD)
VRBO
From $682 per night (USD)
Expedia
3-bedroom house in charming La Mesa with AC
Bedrooms:
2
Bathrooms:
3
Sleeps:
10
Your La Mesa adventure begins at this 3-bedroom house. Each bedroom offers a different bed size - a king, queen, and twi ...
From $682 per night (USD)
Expedia
From $340 per night (USD)
VRBO
Beachy bungalow
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Have fun with the whole family at this stylish place. Within a 20 min drive to the beach, downtown, airport, and the zoo ...
From $340 per night (USD)
VRBO
From $300 per night (USD)
Expedia
Sunset Mesa • Spa• Ac • 10+ Guests •Theatre• Downtown• Beach • 3 Bed/2 Bath
Bedrooms:
2
Bathrooms:
3
Sleeps:
10
Indulge in a serene San Diego escape featuring a private spa and elegant fire pit under the stars. Nestled in a tranquil ...
From $300 per night (USD)
Expedia
From $179 per night (USD)
VRBO
2 bed 2.5 bath Lake Murray Condo - Resort-Style Living in La Mesa
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
Welcome to your fully furnished retreat just steps from Lake Murray! This spacious two-story condo offers 2 large en sui ...
From $179 per night (USD)
VRBO
From $200 per night (USD)
Expedia
Private Casita • No Extra Fees • Spa • Beach • AC
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Escape to a romantic retreat in the heart of San Diego! Just 20 mins to beaches, the Zoo, SeaWorld & Balboa Park, this s ...
From $200 per night (USD)
Expedia
From $412 per night (USD)
VRBO
Sunny La Mesa Family Friendly Home w/ Pool & Spa
Bedrooms:
2
Bathrooms:
3
Sleeps:
9
Welcome to your bright and spacious La Mesa retreat: a thoughtfully designed 3-bedroom, 2-bath home perfect for families ...
From $412 per night (USD)
VRBO
From $336 per night (USD)
Expedia
Charming Hilltop Home · Private Pool · Arcade · Close to Downtown La Mesa
Bedrooms:
1
Bathrooms:
3
Sleeps:
8
Welcome to our 3-bedroom, 1.5-bathroom private pool home with one king bed and two queens. This stunning retreat offers ...
From $336 per night (USD)
Expedia
From $215 per night (USD)
VRBO
5 Mi to SDSU & Trails! Stylish Apartment w/ Patio
Bedrooms:
1
Bathrooms:
3
Sleeps:
6
Seamless Access to I-8 & Highway 125 | 4 Mi to Lake Murray Whether you're visiting loved ones at SDSU or UCSD, hiking ...
From $215 per night (USD)
VRBO
From $514 per night (USD)
Expedia
Cozy ski retreat on Copper Mountain w/artist studio. Pet-Friendly!
Bedrooms:
1
Bathrooms:
1
Sleeps:
6
Hot tub to die for? Convection oven perfect for baking bread? Or maybe the blackout curtains are just perfect for a good ...
From $514 per night (USD)
Expedia
From $174 per night (USD)
VRBO
1BR Walkable to Downtown La Mesa
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Welcome to your fully furnished 1-bedroom retreat steps away from Downtown La Mesa. Nestled in San Diego's "Jewel of the ...
From $174 per night (USD)
VRBO
From $434 per night (USD)
Expedia
King Bed, Big Yard, Prime Area, Ranch, 4BR/3Bth
Bedrooms:
3
Bathrooms:
4
Sleeps:
16
Click the Save button in the top-right corner to easily find us again before your dates are booked. Welcome to our fami ...
From $434 per night (USD)
Expedia
From $160 per night (USD)
VRBO
Cozy Casa | Contemporary 2BR Home · La Mesa
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
Welcome to a brand-new two-bedroom home tucked into the hills of east La Mesa. Finished in 2026, this contemporary space ...
From $160 per night (USD)
VRBO
From $178 per night (USD)
Expedia
Cozy Casa | Private Modern Studio · La Mesa
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Enjoy a stylish experience at this centrally-located contemporary studio. It has its own private entryway and large wind ...
From $178 per night (USD)
Expedia
From $333 per night (USD)
VRBO
3BR La Mesa Home w/Arcade, Parking Near SDSU
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
About this space Bright, Stylish La Mesa Retreat • Private Backyard • Arcade Games • Minutes to SDSU & San Diego Attrac ...
From $333 per night (USD)
VRBO
From $386 per night (USD)
Expedia
Ranch-Style w Gated Yard, 4 Parking, 4 Bedroom 3 Bathroom
Bedrooms:
3
Bathrooms:
4
Sleeps:
16
Welcome to our home! Please read the entire listing carefully before booking. Click the Save button in the top-right cor ...
From $386 per night (USD)
Expedia
From $163 per night (USD)
VRBO
Cozy Casa | La Mesa Private Haven | W/D•Yard•A/C
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Enjoy a bright, newly built Cozy Casa in La Mesa designed for clean, modern living. This private ADU features a light-fi ...
From $163 per night (USD)
VRBO
From $1306 per night (USD)
VRBO
Luxury 6BR Estate - Pool, Spa, Movie Theater, Game Room, Bar, & Outdoor Dining
Bedrooms:
4
Bathrooms:
6
Sleeps:
24
Hey Future Guests :) Thanks for considering our home for your upcoming stay! We want to make sure you have a fantastic ...
From $1306 per night (USD)
VRBO
From $291 per night (USD)
VRBO
Beautiful Sun-Filled Home w/Amazing Views &Balcony
Bedrooms:
2
Bathrooms:
3
Sleeps:
7
Summary: Located within the prestigious Helix Hills neighborhood is this beautiful, sun-filled home offering views out ...
From $291 per night (USD)
VRBO
From $285 per night (USD)
Expedia
Sunny & Spacious 3BR Retreat w/ Parking & A/C
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Summary: Discover your La Mesa retreat! This newly refurbished home offers a perfect blend of comfort and convenience. ...
From $285 per night (USD)
Expedia
From $379 per night (USD)
VRBO
Mediterranean-inspired 1BR Guesthouse - Full Kitchen, Workspace & Garden
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Hey Future Guests :) Thanks for considering our home for your upcoming stay! We want to make sure you have a fantastic ...
From $379 per night (USD)
VRBO
From $662 per night (USD)
Expedia
Sleeps 16 | Mini Golf, 2 Hot Tubs, Theater, Sauna
Bedrooms:
6
Bathrooms:
5
Sleeps:
16
Welcome to La Mesa`s Ultimate Group Getaway! Sleeps 16 with three king bedrooms, featuring mini golf, a movie theater, g ...
From $662 per night (USD)
Expedia
From $279 per night (USD)
VRBO
Luxury 2BR Home in La Mesa Sleeps 5
Bedrooms:
2
Bathrooms:
2
Sleeps:
5
Summary: Enjoy a peaceful getaway in this inviting La Mesa home, tucked into a quiet neighborhood while keeping you clo ...
From $279 per night (USD)
VRBO
From $169 per night (USD)
Expedia
Chic Studio at La Mesa Near SDSU & Muray
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Summary: Affordable private suite in La Mesa, San Diego, perfect for couples, solo travelers, business trips, remote wo ...
From $169 per night (USD)
Expedia

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Results: 112 Rentals