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La Mesa Rentals

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Results: 290 Rentals

  • Quaint La Mesa Home with Beautiful Sunsets!
    From $215 per night (USD)

    VRBO

    Quaint La Mesa Home with Beautiful Sunsets!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Experience 'The Golden State' in the best way possible when you stay at this quiet La Mesa home. Complete with 2 bedroom ...

    From $215 per night (USD)

    VRBO

    Details
  • ***Romantic View Home Centrally Located in Windsor Hills, La Mesa***
    From $298 per night (USD)

    Expedia

    ***Romantic View Home Centrally Located in Windsor Hills, La Mesa***

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    7

    NOTE: VRBO Quote is for the Main House 2B/2B! Beautifully remodeled and newly furnished home in lovely Windsor Hills, c ...

    From $298 per night (USD)

    Expedia

    Details
  • Summer Splash! 4BR La Mesa w/ Pool & Spa Fun
    From $960 per night (USD)

    VRBO

    Summer Splash! 4BR La Mesa w/ Pool & Spa Fun

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    12

    ☆Nestled in the heart of La Mesa, this immaculate home features a private backyard with a pool, spa, fire pit, and fun g ...

    From $960 per night (USD)

    VRBO

    Details
  • Luxury View Home Perfect for San Diego Getaway, Sleeps 12
    From $625 per night (USD)

    Expedia

    Luxury View Home Perfect for San Diego Getaway, Sleeps 12

    Bedrooms:
    4
    Bathrooms:
    4
    Sleeps:
    12

    Newly Updated Property! Relax in this gorgeous home while enjoying incredible ocean views of San Diego and surrounding ...

    From $625 per night (USD)

    Expedia

    Details
  • 3 Bedroom House - Fire Pit Table, BBQ - 10 Guests
    From $256 per night (USD)

    VRBO

    3 Bedroom House - Fire Pit Table, BBQ - 10 Guests

    Bedrooms:
    1
    Bathrooms:
    3
    Sleeps:
    10

    Capture the essence of San Diego in our 3 bedroom house hosted by Ethos Vacation Homes. The peaceful property features e ...

    From $256 per night (USD)

    VRBO

    Details
  • ¡Secret Garden! Pet Friendly Guest Studio La Mesa
    From $145 per night (USD)

    Expedia

    ¡Secret Garden! Pet Friendly Guest Studio La Mesa

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    The Secret Garden Guest Suite Studio – A great place to relax in your own private space located in a quiet neighborhood, ...

    From $145 per night (USD)

    Expedia

    Details
  • New Basement Apartment
    From $133 per night (USD)

    VRBO

    New Basement Apartment

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Brand new 1 bedroom 1 bath basement apartment. Easy freeway access only 15 minutes to Zoo, SeaWorld, Airport, Downtown, ...

    From $133 per night (USD)

    VRBO

    Details
  • XTRA 10% OFF until June: Heated pool, outdoor fire pits, chef's kitchen, gym
    From $484 per night (USD)

    VRBO

    XTRA 10% OFF until June: Heated pool, outdoor fire pits, chef's kitchen, gym

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    9

    Hey there, awesome families looking for fun in San Diego! Imagine this: You wake up in a comfy house perched on a hill, ...

    From $484 per night (USD)

    VRBO

    Details
  • Beautiful Family Getaway | Spa | 15 Min Downtown
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    Expedia

    Beautiful Family Getaway | Spa | 15 Min Downtown

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    -Close to Costco | Vons | Trolley | La Mesa Village | Freeways -Large Backyard Patio | Spa | Gourmet BBQ | Real Grass | ...

    Click For Pricing

    Expedia

    Details
  • Cottage in the Garden. New!  Modern!
    From $152 per night (USD)

    Expedia

    Cottage in the Garden. New! Modern!

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    COTTAGE IN THE GARDEN - New! Modern! Find beauty, privacy and comfort in this special home in one of San Diego's most de ...

    From $152 per night (USD)

    Expedia

    Details
  • San Diego Dream Home, Amazing View, Pool and more!
    From $1000 per night (USD)

    VRBO

    San Diego Dream Home, Amazing View, Pool and more!

    Bedrooms:
    4
    Bathrooms:
    6
    Sleeps:
    16

    VIEWS, VIEWS, VIEWS! The open floor plan allows you to enjoy the spectacular panoramic Ocean, City & Sunset views from m ...

    From $1000 per night (USD)

    VRBO

    Details
  • Welcoming bungalow with den, ideal for longer stays, near everything!
    From $150 per night (USD)

    Expedia

    Welcoming bungalow with den, ideal for longer stays, near everything!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Be at home in this mid-century Craftsman cottage - whip up a great meal in your fully stocked kitchen, snooze in plush c ...

    From $150 per night (USD)

    Expedia

    Details
  • Charming Townhome in the 'Jewel of San Diego Hills' with hot tub, pool, and gym!
    Click For Pricing

    VRBO

    Charming Townhome in the 'Jewel of San Diego Hills' with hot tub, pool, and gym!

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Welcome to your Charming Townhome in the Jewel of the San Diego Hills, your luxurious retreat with breathtaking interior ...

    Click For Pricing

    VRBO

    Details
  • Comfort Casita I Safe Neighborhood, Walking Distance To Cafe
    From $233 per night (USD)

    Expedia

    Comfort Casita I Safe Neighborhood, Walking Distance To Cafe

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    3

    Comfort Casita is located in a safe and quiet neighborhood of La Mesa. We want you to feel like you are on vacation with ...

    From $233 per night (USD)

    Expedia

    Details
  • Family Fun Mountain Villa in San Diego Pool/Jacuzzi, Water-slide, PickleBall
    From $1051 per night (USD)

    VRBO

    Family Fun Mountain Villa in San Diego Pool/Jacuzzi, Water-slide, PickleBall

    Bedrooms:
    4
    Bathrooms:
    5
    Sleeps:
    15

    Escape to this family-friendly luxury villa in the hills of La Mesa, just minutes from San Diego attractions. With spac ...

    From $1051 per night (USD)

    VRBO

    Details
  • Modern Guesthouse Studio✸2-Level Fenced Patio✸Near La Mesa Village✸Pets Welcome
    From $109 per night (USD)

    VRBO

    Modern Guesthouse Studio✸2-Level Fenced Patio✸Near La Mesa Village✸Pets Welcome

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Welcome to our clean and stylish studio within a quiet and charming La Mesa neighborhood! The guesthouse is a fully deta ...

    From $109 per night (USD)

    VRBO

    Details
  • Family Retreat - game room & basketball court in La Mesa
    From $415 per night (USD)

    VRBO

    Family Retreat - game room & basketball court in La Mesa

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    12

    Indoor outdoor living in San Diego at its finest. Entertain and dine outdoors by the grill. There is a game room, basket ...

    From $415 per night (USD)

    VRBO

    Details
  • Hilltop Sanctuary 2-bedroom house in La Mesa with large yard & AC
    From $208 per night (USD)

    Expedia

    Hilltop Sanctuary 2-bedroom house in La Mesa with large yard & AC

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    This hilltop sanctuary in La Mesa is an ideal choice for guests seeking a relaxing retreat with great views and a large ...

    From $208 per night (USD)

    Expedia

    Details
  • Charming studio in delightful La Mesa with WiFi, AC and Deck
    From $122 per night (USD)

    VRBO

    Charming studio in delightful La Mesa with WiFi, AC and Deck

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Your cozy getaway awaits in La Mesa at this adorable studio. This charming space features a comfortable king bed, a mode ...

    From $122 per night (USD)

    VRBO

    Details
  • Friends are Forever by Cardo | Jacuzzi, Sleeps 12
    From $534 per night (USD)

    Expedia

    Friends are Forever by Cardo | Jacuzzi, Sleeps 12

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    12

    Summary: - Private detached cottage with bathroom, arcade machine & TV - Big turf back yard with lawn games - 6 person j ...

    From $534 per night (USD)

    Expedia

    Details
  • Beautiful, spacious and bright
    From $161 per night (USD)

    VRBO

    Beautiful, spacious and bright

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Bright and spacious 1 bed very private apartment,This beautifully designed apartment features an open floor plan, modern ...

    From $161 per night (USD)

    VRBO

    Details
  • Centrally Located Cottage Near Lake Trails Shops
    From $311 per night (USD)

    Expedia

    Centrally Located Cottage Near Lake Trails Shops

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    5

    Centrally located 2 bedroom 1 bathroom San Diego cottage! Easy access to SHOPPING, FOOD, HOSPITALS, LAKES, HIKING TRAILS ...

    From $311 per night (USD)

    Expedia

    Details
  • Artistic Oasis.  Charming 3-bedroom house in La Mesa with AC, WiFi, washer/dryer
    From $205 per night (USD)

    VRBO

    Artistic Oasis. Charming 3-bedroom house in La Mesa with AC, WiFi, washer/dryer

    Bedrooms:
    1
    Bathrooms:
    3
    Sleeps:
    6

    Make yourself at home in this 3-bedroom La Mesa retreat. This amazing house features a king bed, queen bed, and twin bed ...

    From $205 per night (USD)

    VRBO

    Details
  • Sunnyside Resort Spa, Beach, Zoo, Arcade
    From $370 per night (USD)

    Expedia

    Sunnyside Resort Spa, Beach, Zoo, Arcade

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    10

    This enchanting villa in La Mesa is a serene retreat for guests seeking a peaceful getaway. With 3 cozy bedrooms includi ...

    From $370 per night (USD)

    Expedia

    Details
  • Girls  & Family Trip+Pool+beauty bar, San Diego
    From $627 per night (USD)

    VRBO

    Girls & Family Trip+Pool+beauty bar, San Diego

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    10

    Welcome to Le Palmier (The Palm), the remodeled home is perfect for a girls or family trip to San Diego! Escape to a won ...

    From $627 per night (USD)

    VRBO

    Details
  • The Helix Retreat - Private home w trails, pool, river, tiny home & pool house.
    From $900 per night (USD)

    Expedia

    The Helix Retreat - Private home w trails, pool, river, tiny home & pool house.

    Bedrooms:
    5
    Bathrooms:
    7
    Sleeps:
    13

    This 1.2 acre land has multiple dwellings. Large home, 2 story pool house, and a Tiny Home. Great for large groups, retr ...

    From $900 per night (USD)

    Expedia

    Details
  • One bed one bath , fenced yard, and private driveway.
    From $186 per night (USD)

    VRBO

    One bed one bath , fenced yard, and private driveway.

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    3

    A brand new peaceful and quiet house with lots of sunshine! 1 bed 1 bath house, queen bed and twin size roll out bed in ...

    From $186 per night (USD)

    VRBO

    Details
  • Near trolley. NEW charming 1-bedroom home in Fletcher hills, La Mesa.
    From $263 per night (USD)

    Expedia

    Near trolley. NEW charming 1-bedroom home in Fletcher hills, La Mesa.

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Your San Diego adventure begins in this newly built, stylish, 1 bedroom. Just 20 min from the beach, SeaWorld, 7 min ...

    From $263 per night (USD)

    Expedia

    Details
  • Lime Light La Mesa New 4BR 3BA, Group Friendly
    From $425 per night (USD)

    VRBO

    Lime Light La Mesa New 4BR 3BA, Group Friendly

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    13

    Summary: Brand new 4 bed/3 bath vacation home comfortably sleeps up to 13 guests! Enjoy a wonderful outdoor area featur ...

    From $425 per night (USD)

    VRBO

    Details
  • La Mesa Lookout with AC, BBQ, Firepit, Pet Friendly
    From $348 per night (USD)

    Expedia

    La Mesa Lookout with AC, BBQ, Firepit, Pet Friendly

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Summary: Discover your perfect San Diego getaway in La Mesa's charming Windsor Hills! This beautifully appointed home in ...

    From $348 per night (USD)

    Expedia

    Details
  • La Mesa Family Retreat - 20 minutes to Beaches & More!
    From $442 per night (USD)

    VRBO

    La Mesa Family Retreat - 20 minutes to Beaches & More!

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    11

    Welcome to your perfect La Mesa getaway! This spacious three bedroom, three bath home is designed for families and group ...

    From $442 per night (USD)

    VRBO

    Details
  • Spacious 4-BR Home w King Bed, Big Yard in La Mesa
    From $494 per night (USD)

    Expedia

    Spacious 4-BR Home w King Bed, Big Yard in La Mesa

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    16

    Click the Save button in the top-right corner to keep track of our limited availability, while it lasts. I've hosted fo ...

    From $494 per night (USD)

    Expedia

    Details
  • Charming 1-bedroom house on quiet La Mesa street with AC, WiFi
    From $188 per night (USD)

    VRBO

    Charming 1-bedroom house on quiet La Mesa street with AC, WiFi

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    This fully remodeled and stylish guest house has everything you need for a weekend getaway or a longer term stay. Great ...

    From $188 per night (USD)

    VRBO

    Details
  • Stunning SoCal Retreat! New Renovation • Jacuzzi • Luxe Outdoor Lounge
    From $435 per night (USD)

    Expedia

    Stunning SoCal Retreat! New Renovation • Jacuzzi • Luxe Outdoor Lounge

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    Relax with family and friends at this peaceful getaway! Minutes from beaches, downtown San Diego, Balboa Park, and the Z ...

    From $435 per night (USD)

    Expedia

    Details
  • Charming 2-bedroom house with AC, Cozy Retreat with Mountain View
    From $191 per night (USD)

    VRBO

    Charming 2-bedroom house with AC, Cozy Retreat with Mountain View

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    5

    Cozy La Mesa Home | Peaceful Vibes • 10-15 Min to Downtown Tucked in a quiet residential neighborhood, this charming 2- ...

    From $191 per night (USD)

    VRBO

    Details
  • Stylish Terracotta Casita •1 Bedroom and bath • AC •WiFi in delightful La Mesa
    From $145 per night (USD)

    VRBO

    Stylish Terracotta Casita •1 Bedroom and bath • AC •WiFi in delightful La Mesa

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Welcome to Terracotta Casita! Enjoy a stylish and comfortable stay in our brand-new, centrally located apartment—just 9 ...

    From $145 per night (USD)

    VRBO

    Details
  • Luxury View Home Perfect for SD Getaway, Sleeps 12
    From $592 per night (USD)

    VRBO

    Luxury View Home Perfect for SD Getaway, Sleeps 12

    Bedrooms:
    4
    Bathrooms:
    4
    Sleeps:
    12

    Summary: Newly Updated Property! This is the perfect home base for your San Diego getaway. Relax in this gorgeous home ...

    From $592 per night (USD)

    VRBO

    Details
  • Charming bungalow in La Mesa - minutes from SDSU, La Mesa Village
    From $201 per night (USD)

    VRBO

    Charming bungalow in La Mesa - minutes from SDSU, La Mesa Village

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Our charming guest house in La Mesa is located minutes from SDSU, Lake Murray, La Mesa Village, and central San Diego! T ...

    From $201 per night (USD)

    VRBO

    Details
  • Single Level Home by La Mesa Village, Outdoor Deck + 🔥Pit, Fenced Yard for Pets
    From $267 per night (USD)

    VRBO

    Single Level Home by La Mesa Village, Outdoor Deck + 🔥Pit, Fenced Yard for Pets

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    10

    Welcome to this beautifully remodeled single-story home in La Mesa located in a charming neighborhood with plenty of roo ...

    From $267 per night (USD)

    VRBO

    Details
  • Private two bedroom one bath with full kitchen and amazing views!
    From $194 per night (USD)

    VRBO

    Private two bedroom one bath with full kitchen and amazing views!

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    Located in beautiful Mt. Helix area of La Mesa, this private full floor suite with your own entrance features two bedroo ...

    From $194 per night (USD)

    VRBO

    Details
  • Fun Artsy House Large Private Yard Free Parking Bonus Garage Space Ping Pong
    From $326 per night (USD)

    VRBO

    Fun Artsy House Large Private Yard Free Parking Bonus Garage Space Ping Pong

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    7

    Our space has the perfect blend of a vintage feel with a modern touch. With contemporary design & vibrant artwork it emb ...

    From $326 per night (USD)

    VRBO

    Details
  • 2 Bed 2 Bath 15-20 Minutes to all the Best of San Diego!
    From $154 per night (USD)

    Expedia

    2 Bed 2 Bath 15-20 Minutes to all the Best of San Diego!

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    5

    You will have complete access to the entire 2 bed 2 bath home. We benefit from ocean breezes on most days of the year b ...

    From $154 per night (USD)

    Expedia

    Details
  • Quiet, private getaway in a nice neighborhood
    From $147 per night (USD)

    VRBO

    Quiet, private getaway in a nice neighborhood

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Set on top of a hill with a wonderful breeze. It is a private, cozy quaint place. Five minutes from the trolley making i ...

    From $147 per night (USD)

    VRBO

    Details
  • The Best of San Diego! Room to Enjoy, Relax and Recharge!!
    From $183 per night (USD)

    Expedia

    The Best of San Diego! Room to Enjoy, Relax and Recharge!!

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Every room has a microwave, refrigerator, and free WiFi Internet access, and accessible rooms are available. We also off ...

    From $183 per night (USD)

    Expedia

    Details
  • Affordable Escape #4,kitch,yard, pets ok, wifi, 10 min to San Diego
    From $126 per night (USD)

    VRBO

    Affordable Escape #4,kitch,yard, pets ok, wifi, 10 min to San Diego

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Cute, fun, newly remodeled, nicely furnished and conveniently located home. Full Kitchen and separate bedroom with a ki ...

    From $126 per night (USD)

    VRBO

    Details
  • Spacious Home Away From Home
    From $396 per night (USD)

    Expedia

    Spacious Home Away From Home

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    10

    Open and comfy and lightning fast internet best describes this space. In the living room is a ENORMOUS wrap around couch ...

    From $396 per night (USD)

    Expedia

    Details
  • Your Home Away From Home!  10 Minutes to San Diego! Wifi, Kitchen, PetsOK, 1br.
    From $140 per night (USD)

    VRBO

    Your Home Away From Home! 10 Minutes to San Diego! Wifi, Kitchen, PetsOK, 1br.

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    There are two cute, fun, remodeled, nicely furnished and conveniently located duplexes. They are attached with one comm ...

    From $140 per night (USD)

    VRBO

    Details
  • Zen Retreat San Diego
    From $136 per night (USD)

    VRBO

    Zen Retreat San Diego

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Enjoy the feeling of a cozy Zen Retreat on lovely Mt Helix in San Diego county. Mt. Helix is a short 15 minutes from th ...

    From $136 per night (USD)

    VRBO

    Details
  • Travel Writer's Pad
    From $262 per night (USD)

    VRBO

    Travel Writer's Pad

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Hello, Bonjour, Hola, Ciao, Ni Hao! Welcome to Travel Writer's Pad. It’s a pleasure to have you as my guest. For the ...

    From $262 per night (USD)

    VRBO

    Details
  • Your Home Away From Home! 12 min. to SanDiego! Kids & Pets OK!  Kitch/wifi/yard/
    From $118 per night (USD)

    VRBO

    Your Home Away From Home! 12 min. to SanDiego! Kids & Pets OK! Kitch/wifi/yard/

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Nicely furnished and conveniently located home with no attached walls to other units. You, your family and fur buddies ...

    From $118 per night (USD)

    VRBO

    Details
  • Palm Cottage San Diego
    From $332 per night (USD)

    VRBO

    Palm Cottage San Diego

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Charming Craftsman Cottage in the heart of La Mesa Village, San Diego. Enjoy the charm of a historic home with a fully r ...

    From $332 per night (USD)

    VRBO

    Details
  • Quiet peaceful getaway
    From $500 per night (USD)

    Expedia

    Quiet peaceful getaway

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Located at the toe of mt helix surrounded by mountains n trees nice cool breeze constantly flowing, Close freeway acce ...

    From $500 per night (USD)

    Expedia

    Details
  • Hidden King Suite with Garden, Parking - 4 Guest
    From $156 per night (USD)

    VRBO

    Hidden King Suite with Garden, Parking - 4 Guest

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful prope ...

    From $156 per night (USD)

    VRBO

    Details
  • Clean 1BR/1BA Guest House Peaceful Private Casita
    Click For Pricing

    Expedia

    Clean 1BR/1BA Guest House Peaceful Private Casita

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Discover the perfect home away from home in San Diego! Our cozy and tranquil guest house is located just a short drive f ...

    Click For Pricing

    Expedia

    Details
  • Renovated 1 bedroom flat with full kitchen and washer/dryer
    From $90 per night (USD)

    VRBO

    Renovated 1 bedroom flat with full kitchen and washer/dryer

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    3

    Property Description Discover Your Dream Home in San Diego County's Oasis, La Mesa! Step into the allure of our newly r ...

    From $90 per night (USD)

    VRBO

    Details
  • Tastefully Renovated Brand New unit. Walking distance to everything, Lake Murray
    From $307 per night (USD)

    Expedia

    Tastefully Renovated Brand New unit. Walking distance to everything, Lake Murray

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Walking distance to Lake Murray and starbucks. Walking distance to all restaurants and local grocery shops. Everything i ...

    From $307 per night (USD)

    Expedia

    Details
  • Hot Tub and Pickleball at La Mesa Escape
    From $552 per night (USD)

    VRBO

    Hot Tub and Pickleball at La Mesa Escape

    Bedrooms:
    2
    Bathrooms:
    5
    Sleeps:
    10

    Enjoy comfort and fun at our spacious La Mesa home—perfect for families and friends! Play on your own private Pickleball ...

    From $552 per night (USD)

    VRBO

    Details
  • Designer Poolside 1Bed1Bth Retreat
    From $210 per night (USD)

    Expedia

    Designer Poolside 1Bed1Bth Retreat

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Relax at this newly designed poolside guest house in the quiet hills of La Mesa. This beachy one bedroom one bath, has a ...

    From $210 per night (USD)

    Expedia

    Details
  • Unique studio with cozy patio
    From $192 per night (USD)

    VRBO

    Unique studio with cozy patio

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Beautiful and custom studio walkable to the best bars and restaurants in Downtown La Mesa! It features a cozy and spacio ...

    From $192 per night (USD)

    VRBO

    Details
  • An elegant, fully furnished guest house for 2-4 guest in San Diego
    From $272 per night (USD)

    Expedia

    An elegant, fully furnished guest house for 2-4 guest in San Diego

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    3

    Enjoy the ultimate in convenience with this fully furnished unit, in Mt. Helix, La Mesa. Perfectly located within walkin ...

    From $272 per night (USD)

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    Details
  • Groups | 2  Hot Tubs | Game Room
    From $862 per night (USD)

    VRBO

    Groups | 2 Hot Tubs | Game Room

    Bedrooms:
    5
    Bathrooms:
    6
    Sleeps:
    16

    Welcome to The Helix Castle ( IG @HelixCastlelamesa ), nestled in the picturesque hills of La Mesa, California minutes f ...

    From $862 per night (USD)

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    Details
  • Executive Retreat by Cardo | Renovated, Spacious
    From $423 per night (USD)

    Expedia

    Executive Retreat by Cardo | Renovated, Spacious

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    9

    Summary: Recently renovated, this executive home is nothing short of stunning. Enjoy breathtaking 180-degree views of Mt ...

    From $423 per night (USD)

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    Details
  • Charming 2-bedroom house with WiFi and AC in tranquil La Mesa
    From $200 per night (USD)

    VRBO

    Charming 2-bedroom house with WiFi and AC in tranquil La Mesa

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    5

    This 2-bedroom house (duplex) in La Mesa is perfect for your escape to a tranquil retreat. With a king bed and a twin be ...

    From $200 per night (USD)

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    Details
  • SDSU/Downtown <10 Min - GameRoom - Fire Pit - Free Parking - Easy Freeway Access
    From $579 per night (USD)

    Expedia

    SDSU/Downtown <10 Min - GameRoom - Fire Pit - Free Parking - Easy Freeway Access

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    7

    This Vrbo is the perfect home base for small groups/families visiting America's Coolest City! Just a short drive away f ...

    From $579 per night (USD)

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    Details
  • Sun Dial at San Diego \/ Perfect for Summer Fun in San Diego \/ Pet Friendly \/ Sum
    From $435 per night (USD)

    VRBO

    Sun Dial at San Diego \/ Perfect for Summer Fun in San Diego \/ Pet Friendly \/ Sum

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    5

    Summary: Tucked away in the quiet neighborhood of La Mesa, this delightful San Diego Airbnb cottage offers a peaceful es ...

    From $435 per night (USD)

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    Details
  • Charming 3-bedroom house with WiFi, AC in welcoming La Mesa
    From $720 per night (USD)

    Expedia

    Charming 3-bedroom house with WiFi, AC in welcoming La Mesa

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    Stay comfortably in La Mesa at this 3-bedroom house. This charming property features 1 king bed and 2 queen beds, perfec ...

    From $720 per night (USD)

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    Details
  • Private Casita, BBQ + Spa Bath ! 4min to SDSU, 20min to Downtown & Beaches
    From $232 per night (USD)

    VRBO

    Private Casita, BBQ + Spa Bath ! 4min to SDSU, 20min to Downtown & Beaches

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    The Casita at Boho Tides – A Private Guest House Near San Diego’s Top Spots Welcome to Boho Bliss, a newly built 1-bedr ...

    From $232 per night (USD)

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    Details
  • Sunny Retreat Beaches Lakes Trails
    From $979 per night (USD)

    Expedia

    Sunny Retreat Beaches Lakes Trails

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    12

    About this space Bring the whole family to this great place with lots of room for fun. With peaceful and central locati ...

    From $979 per night (USD)

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    Details
  • Sunny Villa Lake Trails Beach
    From $1299 per night (USD)

    VRBO

    Sunny Villa Lake Trails Beach

    Bedrooms:
    3
    Bathrooms:
    6
    Sleeps:
    15

    About this space Nestled in a quiet area and offering ample space, our property is a great option for family and friends ...

    From $1299 per night (USD)

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    Details
  • Sunny Loft Beaches Lakes Trails
    From $762 per night (USD)

    Expedia

    Sunny Loft Beaches Lakes Trails

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    3

    About this space Wake up and have a fresh cup of coffee/tea in your private outdoor area in this peaceful and stylish lo ...

    From $762 per night (USD)

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    Details
  • Private Pool: House + Guest house, Chef’s Kitchen-BBQ - 4min to SDSU, Central SD
    From $650 per night (USD)

    VRBO

    Private Pool: House + Guest house, Chef’s Kitchen-BBQ - 4min to SDSU, Central SD

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    10

    Welcome to Boho Escape, your private San Diego compound featuring two fully detached, single-level homes Boho Tides (Uni ...

    From $650 per night (USD)

    VRBO

    Details
  • Techie Family Stay - Heart of San Diego
    From $382 per night (USD)

    Expedia

    Techie Family Stay - Heart of San Diego

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    The perfect stay for your next family vacation. Centrally located between the cozy charm of La Mesa and the excitement o ...

    From $382 per night (USD)

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    Details
  • Midcentury Dream by Cardo | Jacuzzi Firepit Patio
    From $554 per night (USD)

    VRBO

    Midcentury Dream by Cardo | Jacuzzi Firepit Patio

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    10

    Summary: Welcome to your luxurious home-away-from-home at San Diego's "Jewel of the Hills" in the village of La Mesa! Th ...

    From $554 per night (USD)

    VRBO

    Details
  • Cozy Vintage Trailer with Jacuzzi and Pool in La Mesa
    From $141 per night (USD)

    Expedia

    Cozy Vintage Trailer with Jacuzzi and Pool in La Mesa

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Aloha! If your looking for a relaxing & mellow vibe, We invite you to stay the night in our cozy 1948 16ft Travelo trave ...

    From $141 per night (USD)

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    Details
  • Golden Hour Bliss: Pool, Hot Tub & Firepit
    From $498 per night (USD)

    VRBO

    Golden Hour Bliss: Pool, Hot Tub & Firepit

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    10

    ☀☆ Listing Summary ☆☀ Escape to this stunning 4-bedroom, 3-bath hilltop retreat in La Mesa! Enjoy breathtaking views whi ...

    From $498 per night (USD)

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    Details
  • Welcome to SD Cozy Home - B
    From $197 per night (USD)

    Expedia

    Welcome to SD Cozy Home - B

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Welcome to SD Cozy Home. This Brand New Modern ADU was just created with an Oasis Style. Immerse yourself in our state o ...

    From $197 per night (USD)

    Expedia

    Details
  • Welcome to SD Cozy Home - A
    From $168 per night (USD)

    VRBO

    Welcome to SD Cozy Home - A

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Welcome to SD Cozy Home. This Brand New Modern ADU was just created with an Oasis Style. Immerse yourself in our state o ...

    From $168 per night (USD)

    VRBO

    Details
  • Welcome SD Cozy Suits A & B Together
    From $324 per night (USD)

    Expedia

    Welcome SD Cozy Suits A & B Together

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    8

    Welcome to SD Cozy Suits. This Brand New Modern ADU was just created with an Oasis Style. Immerse yourself in our state ...

    From $324 per night (USD)

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    Details
  • Serene 4BR La Mesa Hideaway
    From $473 per night (USD)

    VRBO

    Serene 4BR La Mesa Hideaway

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    10

    Forget your worries in this spacious and serene four bedroom space with a pool, backyard playground, BBQ, and nostalgia ...

    From $473 per night (USD)

    VRBO

    Details
  • Spacious 4-BR Home, King Bed, Ranch Style, La Mesa
    From $598 per night (USD)

    Expedia

    Spacious 4-BR Home, King Bed, Ranch Style, La Mesa

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    16

    Click the Save button in the top-right corner to keep track of our limited availability, while it lasts. I've hosted fo ...

    From $598 per night (USD)

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    Details
  • Friends are Forever by Cardo Vacation Rentals
    From $586 per night (USD)

    VRBO

    Friends are Forever by Cardo Vacation Rentals

    Bedrooms:
    4
    Bathrooms:
    4
    Sleeps:
    12

    Summary: - Private detached cottage with bathroom, arcade machine & TV - Big turf back yard with lawn games - 6 person j ...

    From $586 per night (USD)

    VRBO

    Details
  • Mid century tiny home in Lovely La Mesa
    From $137 per night (USD)

    Expedia

    Mid century tiny home in Lovely La Mesa

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Your cozy getaway awaits in La Mesa at this mid century house. With a bathroom stocked with essentials like a shower and ...

    From $137 per night (USD)

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    Details
  • The La Mesa Hideaway
    From $163 per night (USD)

    VRBO

    The La Mesa Hideaway

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    3

    Centrally located in a quiet neighborhood close to the best open parks and beaches San Diego has to offer, book your esc ...

    From $163 per night (USD)

    VRBO

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  • 474) Amazing Views + massive pool! Total Oasis
    From $486 per night (USD)

    VRBO

    474) Amazing Views + massive pool! Total Oasis

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Stay at this charming 3-bedroom, 2-bath vacation rental in La Mesa and experience the best of both worlds. Spend your da ...

    From $486 per night (USD)

    VRBO

    Details
  • Beautiful upscale condo with many great amenities!
    From $142 per night (USD)

    VRBO

    Beautiful upscale condo with many great amenities!

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Large living room with leather sofa and 70" TV, a full width balcony with view of the manicured property and pool area. ...

    From $142 per night (USD)

    VRBO

    Details
  • Chic, yet playful boho bungalow near everything!
    From $109 per night (USD)

    Expedia

    Chic, yet playful boho bungalow near everything!

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    3

    This cozy (yup, 'cozy' is a euphemism for small) bungalow has a snazzy vibe. It is flooded with natural light that highl ...

    From $109 per night (USD)

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    Details
  • Designer 4 BR La Mesa Home w/ Yard and BBQ
    From $450 per night (USD)

    VRBO

    Designer 4 BR La Mesa Home w/ Yard and BBQ

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    9

    Relax and enjoy this spacious and elegant La Mesa home! It's recently remodeled with an open kitchen, a modern master be ...

    From $450 per night (USD)

    VRBO

    Details
  • Charming Detached Studio with Private Yard and Laundry
    From $82 per night (USD)

    VRBO

    Charming Detached Studio with Private Yard and Laundry

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Charming, newly renovated modern studio in La Mesa. Located behind a main house, this unit is fully detached complete wi ...

    From $82 per night (USD)

    VRBO

    Details
  • Luxury 5-Bed 3.5-Bath with Pool, Hot Tub, BBQ
    From $690 per night (USD)

    VRBO

    Luxury 5-Bed 3.5-Bath with Pool, Hot Tub, BBQ

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    10

    Summary: Welcome to your La Mesa oasis! This stunning house features a private pool, hot tub, and a game room, perfect f ...

    From $690 per night (USD)

    VRBO

    Details
  • Summer Retreat: Pool, Spa, Games + GuestHouse!
    From $1161 per night (USD)

    Expedia

    Summer Retreat: Pool, Spa, Games + GuestHouse!

    Bedrooms:
    3
    Bathrooms:
    5
    Sleeps:
    16

    ☆Step into this radiant tropical haven and embrace pure vacation bliss! The dazzling pool, soothing spa, tiki lounge, ou ...

    From $1161 per night (USD)

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    Details
  • San Diego Luxury Home w/ Heated Pool and Spa!
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    VRBO

    San Diego Luxury Home w/ Heated Pool and Spa!

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    17

    Renovated and modern home designed for entertaining! Private and spacious backyard with Pool, Spa, BBQ Grill, Fire pit, ...

    Click For Pricing

    VRBO

    Details
  • SD Family Getaway Pool Spa near Lake and Trails
    From $707 per night (USD)

    Expedia

    SD Family Getaway Pool Spa near Lake and Trails

    Bedrooms:
    4
    Bathrooms:
    4
    Sleeps:
    10

    California dreaming come to life in this amazing home located in the tranquil Lake Murray Manor, a great family neighbor ...

    From $707 per night (USD)

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    Details
  • Luxury Home! Heated Pool+Spa+Firepit
    From $930 per night (USD)

    VRBO

    Luxury Home! Heated Pool+Spa+Firepit

    Bedrooms:
    4
    Bathrooms:
    4
    Sleeps:
    10

    Escape from the everyday & enjoy a luxurious vacation in this fully renovated (inside and out) 4-bedroom/3.5 bath home w ...

    From $930 per night (USD)

    VRBO

    Details
  • NEW construction - Studio\n
    Click For Pricing

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    NEW construction - Studio\n

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    3

    Prefer longer stays. Brand new studio - Attached Dwelling Unit (ADU). Walking distance to the Village of La Mesa and clo ...

    Click For Pricing

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    Details
  • Dog-Friendly California Home w/ Patio, Near Hiking
    From $251 per night (USD)

    VRBO

    Dog-Friendly California Home w/ Patio, Near Hiking

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    Indulge in the sunshine when you stay at this charming 2-bedroom, 1-bathroom La Mesa vacation rental! With its fully equ ...

    From $251 per night (USD)

    VRBO

    Details
  • Renovated 3BR Near Downtown SD and San Diego Zoo
    From $282 per night (USD)

    VRBO

    Renovated 3BR Near Downtown SD and San Diego Zoo

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    - Parking for 2 cars - In Unit Washer + Dryer - Central AC + Smart Thermostat - Fully-Equipped Kitchen - Smart TVs ...

    From $282 per night (USD)

    VRBO

    Details
  • Relaxing Retreat with Pool
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    VRBO

    Relaxing Retreat with Pool

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    Welcome to our family friendly, 3 bedroom bungalow situated in the heart of La Mesa San Diego. Located within close walk ...

    Click For Pricing

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    Details
  • La Mesa Vacation Rental ~ 12 Mi to San Diego!
    From $166 per night (USD)

    Expedia

    La Mesa Vacation Rental ~ 12 Mi to San Diego!

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Discover the perfect Southern California getaway when you stay at this 1-bedroom, 1-bathroom vacation rental. Just minut ...

    From $166 per night (USD)

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    Details
  • Hilltop luxe retreat with breathtaking views
    From $299 per night (USD)

    VRBO

    Hilltop luxe retreat with breathtaking views

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    Summary: Welcome to our luxurious contemporary 3 bedroom 2 bathroom home in La Mesa! This stunner offers a spacious and ...

    From $299 per night (USD)

    VRBO

    Details
  • Cozy Mid-Century Charmer - Huge Backyard - Firepit
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    Expedia

    Cozy Mid-Century Charmer - Huge Backyard - Firepit

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Welcome to our fully renovated mid-century home in La Mesa! The perfect location for family vacations or getaways with f ...

    Click For Pricing

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    Details