Matlacha Isles-Matlacha Shores, Florida Vacation Rentals. Book Beach Rentals, Lake Houses, Condos, Cabins, Villas, and Homes in Matlacha Isles-Matlacha Shores, Florida on RentalSaver.com!

Matlacha Isles-Matlacha Shores Rentals

From $459 per night (USD)
VRBO
Amazing sunsets, Fishing from the dock, Large lanai & Pool - Villa Boa Vista - Roelens Vacations
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Villa Boa Vista – Lake Views, Heated Pool & Gulf Access Paradise! Welcome to Villa Boa Vista, your dream escape in sunny ...
From $459 per night (USD)
VRBO
From $186 per night (USD)
Expedia
Pet-Friendly / Family-Friendly Waterfront Vacation Rental + Free Boat Dockage!
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
ANGLER'S INN in Matlacha, Florida is a pet-friendly waterfront "Botel" accommodation located between Cape Coral and Pine ...
From $186 per night (USD)
Expedia
From $139 per night (USD)
VRBO
Studio Redfish Room in Matlacha/Fisherman's Paradise
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Studio "Redfish Room" in a house with 4 apartments, open water - cozy atmosphere in an open living-sleeping area with fu ...
From $139 per night (USD)
VRBO
From $138 per night (USD)
Expedia
Studio Snook Suite in Matlacha/Fisherman's Paradise
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Apartment "Snook Suite" with 4 beds - open living / sleeping area - well equipped kitchen and dining area for 4 persons ...
From $138 per night (USD)
Expedia
From $121 per night (USD)
VRBO
Studio Grouper Room in Matlacha/Fisherman's Paradise
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Studio "Grouper Room" - comfort in the smallest space - living, sleeping, cooking - ideal for singles and couples - well ...
From $121 per night (USD)
VRBO
From $122 per night (USD)
VRBO
Studio Grouper Room in Matlacha/Fisherman's Paradise
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
You will enjoy great days right here in one of the best places on earth! We guarantee the most beautiful sunset of Flor ...
From $122 per night (USD)
VRBO
From $139 per night (USD)
VRBO
Studio Redfish Room in Matlacha/Fisherman's Paradise
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
You will enjoy great days right here in one of the best places on earth! We guarantee the most beautiful sunset of Flor ...
From $139 per night (USD)
VRBO
From $137 per night (USD)
VRBO
Studio snook Suite in Matlacha/Fisherman's Paradise
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
You will enjoy great days right here in one of the best places on earth! We guarantee the most beautiful sunset of Flor ...
From $137 per night (USD)
VRBO
From $139 per night (USD)
VRBO
Studio Redfish Room in Matlacha/Fisherman's Paradise
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
You will enjoy great days right here in one of the best places on earth! We guarantee the most beautiful sunset of Flor ...
From $139 per night (USD)
VRBO
From $122 per night (USD)
Expedia
Studio Grouper Room in Matlacha/Fisherman's Paradise
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
You will enjoy great holiday days right here in one of the best places on earth! We guarantee the most beautiful sunset ...
From $122 per night (USD)
Expedia
From $136 per night (USD)
VRBO
Studio Snook Suite in Matlacha/Fisherman's Paradise
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
You will enjoy great days right here in one of the best places on earth! We guarantee the most beautiful sunset of Flor ...
From $136 per night (USD)
VRBO
From $336 per night (USD)
Expedia
PRIVATE VACATION HOME Cape Coral w/ Heated Saltwater Pool - Spa -Gas Grill
Bedrooms:
3
Bathrooms:
3
Sleeps:
6
Experience Cape Coral like never before all from this gorgeous 3-bedroom, 3-bath villa. This elegant vacation rental boa ...
From $336 per night (USD)
Expedia
From $322 per night (USD)
VRBO
Villa Lago Vista - Waterfront Gem w/ Gulf Access
Bedrooms:
2
Bathrooms:
4
Sleeps:
8
Villa Lago Vista offers expansive and stunning waterfront views of Ceitus Lake, a private heated pool / spa, dog-friendl ...
From $322 per night (USD)
VRBO
From $513 per night (USD)
Expedia
Come visit Boaters Delight in SW Cape-Large Pool/Spa home on canal w/ boatlift!
Bedrooms:
1
Bathrooms:
0
Sleeps:
0
The Boaters Delight is a newer vacation rental located in SW Cape Coral. Located right on a canal with dock, heated pool ...
From $513 per night (USD)
Expedia
From $331 per night (USD)
VRBO
Gulf Access - Heated Pool - Watch manatee & fish from dock
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Located in a quiet friendly neighborhood of NW Cape, this direct gulf access canal home is approx 15 minutes to Matlacha ...
From $331 per night (USD)
VRBO
From $405 per night (USD)
Expedia
Townhome with stunning view of Matlacha Pass
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Stunning Views….A unique town home community nestled on the island of Matlacha. This Matlacha location is literally minu ...
From $405 per night (USD)
Expedia
From $371 per night (USD)
VRBO
Palm Pointe - Waterfront Vacation Rental Cape Cora
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Welcome to Palm Pointe Palm Pointe is a gorgeous, three-bedroom, 2 1/2-bathroom vacation villa situated in the northern ...
From $371 per night (USD)
VRBO
Click For Pricing
Expedia
Beautiful Water Views, Tropical Sunsets, Gulf Access - Villa Island Escape - Roelens Vacations
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
VILLA ISLAND ESCAPE Your Tropical Island Getaway Starts Here! Welcome to Villa Island Escape—a dreamy waterfront haven ...
Click For Pricing
Expedia
From $396 per night (USD)
VRBO
Heated Pool + Lanai: Matlacha Isles Getaway
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
An unforgettable Matlacha Isles getaway awaits at this radiant 3-bedroom, 2.5-bathroom vacation rental. The vibrant home ...
From $396 per night (USD)
VRBO
From $727 per night (USD)
Expedia
Waterfront home with private pool, dock, patio, balconies, & bikes
Bedrooms:
3
Bathrooms:
4
Sleeps:
12
Maison de Sirens Our calendar is updated in real-time & our nightly rates are accurately displayed. Simply enter your d ...
From $727 per night (USD)
Expedia
From $487 per night (USD)
VRBO
VRCC Villa Paradisio
Bedrooms:
3
Bathrooms:
4
Sleeps:
12
website: www.vr-capecoral.com Villa Paradisio - Located less than 500 yards from the Stonis Park, Restaurants, Tennis C ...
From $487 per night (USD)
VRBO
Click For Pricing
Expedia
Intervillas Florida - Villa Royal Sereni Tee
Bedrooms:
3
Bathrooms:
4
Sleeps:
8
NEW Vacation Home - Villa Royal Sereni Tee "As you enter Cape Royal Country Club, you're welcomed by a line of palm tre ...
Click For Pricing
Expedia
From $271 per night (USD)
VRBO
3BR Waterfront townhome Matlacha with hot tub, boat dock WiFi, bikes and kayaks
Bedrooms:
2
Bathrooms:
3
Sleeps:
5
Located in Matlacha, enjoy what this 3-bedroom 2 full bath townhome has to offer. With 1 queen bed, 1 king bed, and 1 tw ...
From $271 per night (USD)
VRBO
From $343 per night (USD)
Expedia
Welcome to Villa Lahaina – your perfect tropical getaway
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Discover the epitome of comfort and coziness in this 3-bedroom, 2-bathroom haven that invites you to experience the best ...
From $343 per night (USD)
Expedia
From $324 per night (USD)
VRBO
Kayaks, Bicycles, Pool, Gulf Access: Endless Summer Feelings
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Welcome to your secret haven of bliss in Southwest Cape Coral! This 3-bedroom, 2-bathroom dream home is your personal sa ...
From $324 per night (USD)
VRBO
From $225 per night (USD)
Expedia
3/3 Home in Matlacha with Downstairs Suite! Incredible Views!
Bedrooms:
3
Bathrooms:
3
Sleeps:
6
Check out this 2/2 in the heart of Matlacha! Two bedrooms upstairs with deck overlooking open water and 1 bedroom suite ...
From $225 per night (USD)
Expedia
From $189 per night (USD)
VRBO
All new, incredible location! Waterfront unit in Matlacha with many amenities.
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Professional, full renovation completed Aug 2025. 1 bed, 1 bath with additional queen pullout sofa bed in the living roo ...
From $189 per night (USD)
VRBO
From $482 per night (USD)
Expedia
GULF ACCESS & BIG WATER VIEW!, Heated Saltwater Pool and Spa - Villa Manatees Crossing - Roelens
Bedrooms:
4
Bathrooms:
4
Sleeps:
11
VILLA MANATEES CROSSING BIG WATER VIEW AWAITS! Calling all boating and fishing enthusiasts—your dream vacation starts h ...
From $482 per night (USD)
Expedia
From $215 per night (USD)
VRBO
Priceless Waterfront Escape in Matlacha
Bedrooms:
1
Bathrooms:
2
Sleeps:
7
Discover island living at our newly-remodeled waterfront escape in Matlacha on a deep water canal with a private dock (l ...
From $215 per night (USD)
VRBO
From $246 per night (USD)
VRBO
Waterfront Island Paradise-Entire Home on Gulf Access Canal
Bedrooms:
2
Bathrooms:
2
Sleeps:
4
Chic beachy 2 bedroom 2 bathroom private pool home on a direct gulf access canal. Cool off, Kick back, and relax in t ...
From $246 per night (USD)
VRBO
From $361 per night (USD)
VRBO
Endless Fun In The Sun
Bedrooms:
2
Bathrooms:
4
Sleeps:
8
Welcome to your perfect Cape Coral getaway! Our spacious 4-bedroom, 2-bath home is designed for relaxation, adventure, a ...
From $361 per night (USD)
VRBO
From $212 per night (USD)
Expedia
Million Dollar View Lakefront Home in Cape Coral
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Villa Cape Royal, located in the gated community of the same name, is an oasis far away from the stress of everyday life ...
From $212 per night (USD)
Expedia
From $495 per night (USD)
VRBO
Beautiful waterfront home with pool/spa, boat lift, kayaks and kayak launch!
Bedrooms:
2
Bathrooms:
2
Sleeps:
7
Island home with direct access to Matlacha Pass. A 2-story property equipped with a pool and spa, high-speed internet, s ...
From $495 per night (USD)
VRBO
From $210 per night (USD)
Expedia
Newly remodeled home with heated pool and pool spa, gas grill, & W/D - dogs ok
Bedrooms:
2
Bathrooms:
3
Sleeps:
7
Little EsCape Our calendar is updated in real-time & our nightly rates are accurately displayed. Simply enter your desi ...
From $210 per night (USD)
Expedia
$Matlacha Cottage 2/2 remodeled& sunsets!\n$
From $261 per night (USD)
VRBO
Matlacha Cottage 2/2 remodeled& sunsets!\n
Bedrooms:
2
Bathrooms:
2
Sleeps:
4
Welcome to The Matlacha Cottages, a serene and unique open water getaway, perfect for solo travelers or couples. This ma ...
From $261 per night (USD)
VRBO
From $280 per night (USD)
Expedia
Cape Coral 4 Bedroom Private Pool Home
Bedrooms:
2
Bathrooms:
4
Sleeps:
8
Cape Coral Private Pool Vacation Home - Across the street from Seven Islands Recreation Area Our 4-bedroom, 2-bathroom ...
From $280 per night (USD)
Expedia
Click For Pricing
VRBO
Matlacha Island House
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
Come experience the colorful charm and laid back style of Matlacha! This beautiful, bright and clean 2 bedroom, 2 bath ...
Click For Pricing
VRBO
From $462 per night (USD)
Expedia
Island Cottage in Quaint Matlacha Florida. Amazing island life is a click away…
Bedrooms:
2
Bathrooms:
3
Sleeps:
8
This cozy, 3 bedroom bungalow cottage is nestled on a peninsula located in the heart of Matlacha Florida. With the conve ...
From $462 per night (USD)
Expedia
From $295 per night (USD)
VRBO
Cape Coral Oasis - Entire Home in Cape Coral, Florida - features pool & hot tub
Bedrooms:
3
Bathrooms:
4
Sleeps:
8
Just off Burnt Store Road, moments away from a boat ramp, shopping, restaurants, and water park...but our home is on a q ...
From $295 per night (USD)
VRBO
From $327 per night (USD)
Expedia
Tropical Gulf-Access Hideaway
Bedrooms:
3
Bathrooms:
4
Sleeps:
12
Welcome to your Florida dream vacation! This spacious 4-bedroom, 2.5-bath waterfront home offers the perfect mix of rela ...
From $327 per night (USD)
Expedia
From $228 per night (USD)
VRBO
Sunset Retreat on Matlacha. Charming 2/1 house on Matlacha Pass.
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
Welcome to our cozy 2-bedroom, 1-bathroom waterfront retreat in the heart of Matlacha, Florida! Nestled on the serene wa ...
From $228 per night (USD)
VRBO
From $123 per night (USD)
VRBO
Studio Snapper Room in Matlacha/Fisherman's Paradise
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
You will enjoy a great time right here in one of the best places on earth! We guarantee the most beautiful sunset of Fl ...
From $123 per night (USD)
VRBO
From $124 per night (USD)
VRBO
Studio Snapper Room in Matlacha/Fisherman's Paradise
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
You will enjoy a great time right here in one of the best places on earth! We guarantee the most beautiful sunset of Fl ...
From $124 per night (USD)
VRBO
From $123 per night (USD)
Expedia
Studio Snapper Room in Matlacha/Fisherman's Paradise
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
<p>Located on the waterfront, this welcoming vacation home lets you experience it all in Matlacha. Lovegrove Gallery & G ...
From $123 per night (USD)
Expedia
Click For Pricing
VRBO
Heart of Matlacha Studio-remodeled! NEW
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
It's rare to find a place that's both historic and one-of-a-kind. It’s even rarer to find a place that is historic, uniq ...
Click For Pricing
VRBO
From $289 per night (USD)
Expedia
Welcome to Lake Residence
Bedrooms:
3
Bathrooms:
4
Sleeps:
8
We wish to share our luxuries vacation home in desirable SW Cape Coral located on a 400 ft wide lake with easy access to ...
From $289 per night (USD)
Expedia
From $207 per night (USD)
VRBO
Magnificent Lakeside Home
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Welcome to this beautiful Home, located on a Lake with Panoramic views of the lake from each room. There is an above av ...
From $207 per night (USD)
VRBO

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Matlacha Isles-Matlacha Shores Rentals

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Results: 147 Rentals