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Results: 539 Rentals

  • Mill Place Cabin Getaway
    From $256 per night (USD)

    VRBO

    Mill Place Cabin Getaway

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    The Cabin is a mountain getaway with a large stream & peaceful views. It's a great place to unplug & escape the crowds. ...

    From $256 per night (USD)

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    Details
  • The Yellow Quilt in Walhalla
    From $241 per night (USD)

    VRBO

    The Yellow Quilt in Walhalla

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Our newly renovated early 1900s home in Walhalla is affectionately called the Yellow Quilt. It accommodates a larger fam ...

    From $241 per night (USD)

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    Details
  • A Lakefront Tiny Cabin: Hot tub, Kayaks, SUP, Canoe, Hike, Near Jocassee
    From $307 per night (USD)

    VRBO

    A Lakefront Tiny Cabin: Hot tub, Kayaks, SUP, Canoe, Hike, Near Jocassee

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Whitewater Cabin – Lakefront Tiny Retreat Near Jocassee and Lake Keowee Escape to the mountains and unwind at Whitewate ...

    From $307 per night (USD)

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  • Lakefront Escape close to Clemson and Seneca
    From $366 per night (USD)

    Expedia

    Lakefront Escape close to Clemson and Seneca

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    10

    Gather your friends and family and enjoy our Lakehouse and dock. located just 7 miles from Clemson University. 4 separat ...

    From $366 per night (USD)

    Expedia

    Details
  • Hanover Haven Motorhome
    From $120 per night (USD)

    VRBO

    Hanover Haven Motorhome

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    This memorable place is anything but ordinary. The motorhome is only 3 miles from Clemson’s Death Valley. You will be on ...

    From $120 per night (USD)

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    Details
  • Lake Keowee: Lake front 7 mi from Clemson stadium
    From $662 per night (USD)

    VRBO

    Lake Keowee: Lake front 7 mi from Clemson stadium

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    10

    Comfortable, newly remodeled open plan house on Lake Keowee- south end -10 minute drive from Clemson's Death Valley or a ...

    From $662 per night (USD)

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    Details
  • Lakefront luxury on Lake Keowee.
    From $1367 per night (USD)

    VRBO

    Lakefront luxury on Lake Keowee.

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    12

    Beautiful new custom home on Lake Keowee. Nestled in a picturesque cove with stunning sunrises and calm waters. Built ...

    From $1367 per night (USD)

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    Details
  • Hanover Haven 3 BR/2 Bath
    From $194 per night (USD)

    VRBO

    Hanover Haven 3 BR/2 Bath

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    Hanover Haven is perfectly located for all your needs! Clemson University is only 3 miles away. There are 3 full grocer ...

    From $194 per night (USD)

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    Details
  • Home on Lake Hartwell - Lake Life with wraparound porches, fire pit and dock
    From $444 per night (USD)

    VRBO

    Home on Lake Hartwell - Lake Life with wraparound porches, fire pit and dock

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    10

    Lake front home with 4 bedrooms and 3 full baths which includes a finished basement. House has wraparound screen porch ...

    From $444 per night (USD)

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  • Family Getaway - Lake Keowee
    From $519 per night (USD)

    VRBO

    Family Getaway - Lake Keowee

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    10

    Welcome home to Green Point Villa! Our home is ready to welcome you for lake fun and relaxation, Springtime with the fam ...

    From $519 per night (USD)

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    Details
  • Sunrise Retreat on Lake Keowee with Hot Tub!
    From $977 per night (USD)

    VRBO

    Sunrise Retreat on Lake Keowee with Hot Tub!

    Bedrooms:
    4
    Bathrooms:
    5
    Sleeps:
    14

    Welcome to Sunrise Retreat on Lake Keowee, a place for family and friends to be together!  This newly constructed home ...

    From $977 per night (USD)

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    Details
  • Stunning Seneca Home w/ Lake Keowee Access!
    From $561 per night (USD)

    Expedia

    Stunning Seneca Home w/ Lake Keowee Access!

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    10

    With the shoreline just steps away and endless waterfront activities at your fingertips, this 4-bedroom, 2.5-bath vacati ...

    From $561 per night (USD)

    Expedia

    Details
  • Lake front Keowee Condo w/ Balcony & Resort Amenities! (20 min to Clemson) by RedAwning
    From $359 per night (USD)

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    Lake front Keowee Condo w/ Balcony & Resort Amenities! (20 min to Clemson) by RedAwning

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    6

    **Gated Keowee Key Condo on lake Keowee. 2 bedrooms, 2 bath. Great location!!!** This unique condo is steps from the ...

    From $359 per night (USD)

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    Details
  • What a family lake house should be! Natural Beauty w/ space for each to enjoy!!!
    From $826 per night (USD)

    Expedia

    What a family lake house should be! Natural Beauty w/ space for each to enjoy!!!

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    12

    Quiet DEEP water Cove on private acre lot. Large covered dock for sunning, boat and 2 jet ski docks. 4 Hammocks to enjoy ...

    From $826 per night (USD)

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  • Lakefront Cottage on Serene Lake Becky
    From $355 per night (USD)

    VRBO

    Lakefront Cottage on Serene Lake Becky

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    From the moment you walk in the front door of our completely restored 1967 lakefront cottage, you can see the lake all t ...

    From $355 per night (USD)

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    Details
  • Rustic Escape on Lake Hartwell - Pet Friendly, Kayaks and Paddleboards Provided!
    From $304 per night (USD)

    Expedia

    Rustic Escape on Lake Hartwell - Pet Friendly, Kayaks and Paddleboards Provided!

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    11

    Come escape the busyness of every day life at our cozy lake house. Comfortably sleeps 11, making it perfect for the whol ...

    From $304 per night (USD)

    Expedia

    Details
  • Lake Hartwell minutes to Clemson and a Salt Water Pool.
    From $586 per night (USD)

    VRBO

    Lake Hartwell minutes to Clemson and a Salt Water Pool.

    Bedrooms:
    4
    Bathrooms:
    5
    Sleeps:
    14

    Absolutely no parties or large gatherings allowed at the house. Beautifully located on a quite finger of the lake and ea ...

    From $586 per night (USD)

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    Details
  • Captains Walk 103: Cozy 2BR condo in Keowee Key, perfect for a relaxing getaway.
    From $389 per night (USD)

    Expedia

    Captains Walk 103: Cozy 2BR condo in Keowee Key, perfect for a relaxing getaway.

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    Welcome to Captains Walk 103, a charming condo nestled in the beautiful Keowee Key community of Salem, South Carolina. T ...

    From $389 per night (USD)

    Expedia

    Details
  • Tall Ship 304 Keowee Key
    From $424 per night (USD)

    VRBO

    Tall Ship 304 Keowee Key

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    4

    Welcome to Tall Ship 304, a stunning condo nestled in the picturesque Keowee Key community of Salem, South Carolina. Thi ...

    From $424 per night (USD)

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    Details
  • La Cabaña- The Cabin in Long Creek
    From $467 per night (USD)

    VRBO

    La Cabaña- The Cabin in Long Creek

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    6

    Live the Appalachian dream at La Cabaña, our hand-crafted log cabin in the gorgeous foothills of Long Creek SC. Every d ...

    From $467 per night (USD)

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    Details
  • Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
    From $354 per night (USD)

    VRBO

    Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    8

    Escape to a lakeside retreat just 5 minutes from downtown Seneca. Our 3-bedroom, 3-bathroom home offers the perfect plac ...

    From $354 per night (USD)

    VRBO

    Details
  • Keowee Keys Condo w/ Resort Amenities Access!
    From $362 per night (USD)

    Expedia

    Keowee Keys Condo w/ Resort Amenities Access!

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    6

    Experience luxurious lake life when you stay at this Salem vacation rental! This 2-bedroom, 2-bath condo features a love ...

    From $362 per night (USD)

    Expedia

    Details
  • Lakefront Westminster Retreat w/ Boat Dock!
    From $416 per night (USD)

    VRBO

    Lakefront Westminster Retreat w/ Boat Dock!

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    With the shoreline just steps away, you’ll never want to leave this vacation rental on Lake Hartwell! This 3-bedroom, 2- ...

    From $416 per night (USD)

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    Details
  • Woodhaven 150: A stunning 4-bedroom lakefront retreat
    From $1066 per night (USD)

    Expedia

    Woodhaven 150: A stunning 4-bedroom lakefront retreat

    Bedrooms:
    4
    Bathrooms:
    4
    Sleeps:
    12

    Welcome to Woodhaven 150, a stunning lakefront haven nestled on the serene shores of Lake Keowee in West Union, South Ca ...

    From $1066 per night (USD)

    Expedia

    Details
  • Amazing Lake  / Mountain Setting
    From $422 per night (USD)

    VRBO

    Amazing Lake / Mountain Setting

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    10

    Relax with the whole family at this peaceful place on Lake Hartwell. Far enough to get away, close enough to want to sta ...

    From $422 per night (USD)

    VRBO

    Details
  • Carolina’s Cottage Cove-Lake Keowee
    From $2120 per night (USD)

    Expedia

    Carolina’s Cottage Cove-Lake Keowee

    Bedrooms:
    5
    Bathrooms:
    6
    Sleeps:
    21

    Heaven on earth. This brand new beautifully designed and decorated home with everything you need to make amazing memori ...

    From $2120 per night (USD)

    Expedia

    Details
  • Tall Ship 331 Keowee Key
    From $424 per night (USD)

    VRBO

    Tall Ship 331 Keowee Key

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    4

    Welcome to Tall Ship 331, a stunning two-bedroom condo nestled in the picturesque Keowee Key community of Salem, South C ...

    From $424 per night (USD)

    VRBO

    Details
  • Cozy Lakefront A-Frame Cabin Lake Hartwell Clemson
    From $564 per night (USD)

    Expedia

    Cozy Lakefront A-Frame Cabin Lake Hartwell Clemson

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    8

    The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, ...

    From $564 per night (USD)

    Expedia

    Details
  • Marina Village 338 In Keowee Key
    From $424 per night (USD)

    VRBO

    Marina Village 338 In Keowee Key

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    4

    Marina Village is a townhome community located inside the gates of beautiful Keowee Key. As a guest, you can access all ...

    From $424 per night (USD)

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    Details
  • Residences on Main Issqueena Suite
    From $268 per night (USD)

    VRBO

    Residences on Main Issqueena Suite

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Enjoy a great experience at the newly renovated and centrally-located Residences on Main that are walking distance to re ...

    From $268 per night (USD)

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    Details
  • Clear Sail Way Haven
    From $1701 per night (USD)

    VRBO

    Clear Sail Way Haven

    Bedrooms:
    5
    Bathrooms:
    6
    Sleeps:
    14

    The living room boasts of high ceilings with lovely craftsman style beams opening to the very spacious kitchen with a la ...

    From $1701 per night (USD)

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    Details
  • Residences on Main- Yellow Branch Suite
    From $279 per night (USD)

    VRBO

    Residences on Main- Yellow Branch Suite

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Enjoy a stylish experience at the newly renovated and centrally-located Residences on Main that are walking distance to ...

    From $279 per night (USD)

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    Details
  • Beached Houseboat-Free Park Pass
    From $195 per night (USD)

    VRBO

    Beached Houseboat-Free Park Pass

    Bedrooms:
    0
    Bathrooms:
    2
    Sleeps:
    4

    You'll love this unique and romantic escape. come aboard our awesome Houseboat on land- This perfectly restored rustic y ...

    From $195 per night (USD)

    VRBO

    Details
  • Hidden Lake Sanctuary
    From $358 per night (USD)

    Expedia

    Hidden Lake Sanctuary

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    10

    Recently remodeled and boasting 3000 sq ft, this home offers comfort and serenity. Tucked away in a peaceful cove feedin ...

    From $358 per night (USD)

    Expedia

    Details
  • Lake Hartwell Cabin, Perfect for Clemson Game Day
    From $806 per night (USD)

    VRBO

    Lake Hartwell Cabin, Perfect for Clemson Game Day

    Bedrooms:
    6
    Bathrooms:
    6
    Sleeps:
    10

    Experience the ultimate game day getaway at this 6-bedroom, 6-bathroom Fair Play vacation rental! Boasting direct access ...

    From $806 per night (USD)

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    Details
  • Lakefront home w/covered dock-Pool table-Kayak/SUP-11mi to Clemson-Hot tub
    From $675 per night (USD)

    Expedia

    Lakefront home w/covered dock-Pool table-Kayak/SUP-11mi to Clemson-Hot tub

    Bedrooms:
    4
    Bathrooms:
    5
    Sleeps:
    14

    This is the perfect family vacation spot! Newly built 3300 sq ft home on Lake Hartwell Spacious 5Bd/4Ba, 2 level home sl ...

    From $675 per night (USD)

    Expedia

    Details
  • Chauga River Cabin: Pets Welcome!
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    VRBO

    Chauga River Cabin: Pets Welcome!

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    Chauga River On-Site | Hiking Trails & Fly Fishing Nearby | Weber Charcoal Grill Escape to the foothills for a serene s ...

    Click For Pricing

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  • Log Cabin in the Foothills of the Blue Ridge Mountains, Lake Jocassee - Keowee
    From $299 per night (USD)

    VRBO

    Log Cabin in the Foothills of the Blue Ridge Mountains, Lake Jocassee - Keowee

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    Just enough space to be cozy & comfortable with 2 bedrooms, 1 1/2 baths, plenty of parking for your boats/ATVs, big truc ...

    From $299 per night (USD)

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  • Tiny House/w outdoor cast-iron shower/tub
    From $164 per night (USD)

    VRBO

    Tiny House/w outdoor cast-iron shower/tub

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Romantic Tiny house Get away or bring the kids! Enjoy a soak in the outdoor cast-iron tub with beautiful sunsets over th ...

    From $164 per night (USD)

    VRBO

    Details
  • Cane Creek Retreat on Lake Keowee by Clemson Vacation Rentals!
    From $1148 per night (USD)

    Expedia

    Cane Creek Retreat on Lake Keowee by Clemson Vacation Rentals!

    Bedrooms:
    4
    Bathrooms:
    5
    Sleeps:
    14

    Welcome to Cane Creek Retreat on Beautiful Lake Keowee in the Upcountry of South Carolina! Escape to Cane Creek Retreat ...

    From $1148 per night (USD)

    Expedia

    Details
  • Perfect lake property for Clemson Game Day!
    From $690 per night (USD)

    VRBO

    Perfect lake property for Clemson Game Day!

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    9

    Enjoy everything that lake life has to offer, only 20 minutes from Clemson's Memorial Stadium. This home provides maximu ...

    From $690 per night (USD)

    VRBO

    Details
  • Serenity Bay Lakefront Cabin w/ Boat Slip.
    From $501 per night (USD)

    VRBO

    Serenity Bay Lakefront Cabin w/ Boat Slip.

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    8

    This beautiful log cabin lake home is a 3 story lake home stay that will be sure to be your home away from home. Guests ...

    From $501 per night (USD)

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    Details
  • Pet-Friendly Lakefront Retreat • Hot Tub, Sandy Shore & Fenced Yard
    From $283 per night (USD)

    VRBO

    Pet-Friendly Lakefront Retreat • Hot Tub, Sandy Shore & Fenced Yard

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Welcome to Dream Weaver Cottage, your private Lake Hartwell retreat designed for slowing down, reconnecting, and making ...

    From $283 per night (USD)

    VRBO

    Details
  • Brand New 6BR/6BA Luxury, 20min to Clemson. Wooded flat lot/firepit/pool table!
    From $776 per night (USD)

    Expedia

    Brand New 6BR/6BA Luxury, 20min to Clemson. Wooded flat lot/firepit/pool table!

    Bedrooms:
    6
    Bathrooms:
    6
    Sleeps:
    14

    Home and floor plan nearly identical to another one of our very popular homes, VRBO listing #2386961, but these are two ...

    From $776 per night (USD)

    Expedia

    Details
  • Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson
    From $1440 per night (USD)

    VRBO

    Family Retreat on South Cove of Lake Keowee; Private Dock; ~ 10 Mi from Clemson

    Bedrooms:
    3
    Bathrooms:
    5
    Sleeps:
    14

    Welcome to this newly renovated lakefront retreat, nestled on the south end of picturesque Lake Keowee. This stunning ho ...

    From $1440 per night (USD)

    VRBO

    Details
  • South Cove Cottage 5 bedroom
    From $508 per night (USD)

    VRBO

    South Cove Cottage 5 bedroom

    Bedrooms:
    2
    Bathrooms:
    5
    Sleeps:
    10

    Welcome to our stunning 5-bedroom home with a cove view of beautiful Lake Keowee! Nestled in a quiet cove, this spacious ...

    From $508 per night (USD)

    VRBO

    Details
  • Perfect Summer get away! Charming 4 bedroom lake front home.
    From $548 per night (USD)

    VRBO

    Perfect Summer get away! Charming 4 bedroom lake front home.

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    12

    Welcome to Doc's Place! This amazing lakefront house has a tranquil setting on a quiet cul-de-sac. This 4 bedroom hous ...

    From $548 per night (USD)

    VRBO

    Details
  • Walk to Lake Keowee: Salem Townhome w/ Deck
    From $408 per night (USD)

    Expedia

    Walk to Lake Keowee: Salem Townhome w/ Deck

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    10

    Walk to Private Beach | Fireplace | Newly Renovated | 10 Mi to Clemson Escape to this 4-bedroom, 3-bath vacation rental ...

    From $408 per night (USD)

    Expedia

    Details
  • Cozy Fair Play Home w/ Deck 4 Mi to Lake Hartwell!
    From $196 per night (USD)

    VRBO

    Cozy Fair Play Home w/ Deck 4 Mi to Lake Hartwell!

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Escape to Fair Play, SC, with this cozy-modern vacation rental — perfect for couples or small families! This 1-bedroom, ...

    From $196 per night (USD)

    VRBO

    Details
  • Turtlehead 520: Luxurious 6BR retreat in scenic Salem, SC, perfect for family getaways.
    From $2423 per night (USD)

    Expedia

    Turtlehead 520: Luxurious 6BR retreat in scenic Salem, SC, perfect for family getaways.

    Bedrooms:
    6
    Bathrooms:
    6
    Sleeps:
    12

    Welcome to the exquisite Turtlehead Retreat, a stunning waterfront property nestled in the serene surroundings of Lake K ...

    From $2423 per night (USD)

    Expedia

    Details
  • Keowee Waterfront Lakeside Retreat -Keowee Cottage
    From $346 per night (USD)

    VRBO

    Keowee Waterfront Lakeside Retreat -Keowee Cottage

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    4

    Lake Keowee Lake Side Retreat! Keowee Cottage is nestled in a lovely cove on a privately owned 20+ acre property. Explor ...

    From $346 per night (USD)

    VRBO

    Details
  • Wakeboard Run on Lake Keowee- with dock + Firepit + sleeps 14
    From $554 per night (USD)

    VRBO

    Wakeboard Run on Lake Keowee- with dock + Firepit + sleeps 14

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    10

    Welcome to Wake Board Run- a fun, stylish lake house located on the beautiful shores of Lake Keowee. This charming home ...

    From $554 per night (USD)

    VRBO

    Details
  • Luxury Lake Keowee Retreat, Private Dock, Near Clemson - Sleeps 12
    From $1361 per night (USD)

    VRBO

    Luxury Lake Keowee Retreat, Private Dock, Near Clemson - Sleeps 12

    Bedrooms:
    4
    Bathrooms:
    5
    Sleeps:
    12

    Experience the best of Lake Keowee from this stunning luxury lakefront retreat, tucked away on a peaceful cove and your ...

    From $1361 per night (USD)

    VRBO

    Details
  • Lakefront Fair Play Vacation Rental, Pets Welcome!
    From $410 per night (USD)

    Expedia

    Lakefront Fair Play Vacation Rental, Pets Welcome!

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    Escape to Fair Play with your family or friends and book this 3-bed, 2-bath vacation rental! This home features 5 Smart ...

    From $410 per night (USD)

    Expedia

    Details
  • Perfect Keowee Getaway - Close to Clemson & Seneca
    From $639 per night (USD)

    VRBO

    Perfect Keowee Getaway - Close to Clemson & Seneca

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    9

    Lakefront vacation home, perfect for a family get-away! This cozy lakefront vacation home is less than 25 yards from a ...

    From $639 per night (USD)

    VRBO

    Details
  • Boutique hotel in historic downtown Seneca. Room #2 Owners Suite. Q/K combo.
    From $215 per night (USD)

    Expedia

    Boutique hotel in historic downtown Seneca. Room #2 Owners Suite. Q/K combo.

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Welcome to the heart of downtown Seneca, South Carolina. Formerly the Richardson Theatre in the late 50s, our building ...

    From $215 per night (USD)

    Expedia

    Details
  • Boutique hotel in historic downtown Seneca. Room #4, King bed.
    From $220 per night (USD)

    VRBO

    Boutique hotel in historic downtown Seneca. Room #4, King bed.

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Welcome to the heart of downtown Seneca, South Carolina. Formerly the Richardson Theatre in the late 50s, our building ...

    From $220 per night (USD)

    VRBO

    Details
  • Private Room #3
    From $204 per night (USD)

    Expedia

    Private Room #3

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Welcome to the heart of downtown Seneca, South Carolina. Formerly the Richardson Theatre in the late 50s, our building ...

    From $204 per night (USD)

    Expedia

    Details
  • Boutique hotel in historic downtown Seneca. Room #6, King Bed.
    From $220 per night (USD)

    VRBO

    Boutique hotel in historic downtown Seneca. Room #6, King Bed.

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    2

    Welcome to the heart of downtown Seneca, South Carolina. Formerly the Richardson Theatre in the late 50s, our building ...

    From $220 per night (USD)

    VRBO

    Details
  • Boutique hotel in historic downtown Seneca. Room #5, two King beds.
    From $204 per night (USD)

    Expedia

    Boutique hotel in historic downtown Seneca. Room #5, two King beds.

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Welcome to the heart of downtown Seneca, South Carolina. Formerly the Richardson Theatre in the late 50s, our building ...

    From $204 per night (USD)

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  • Boutique hotel in historic downtown Seneca. Room#1, Q/K combo.
    From $204 per night (USD)

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    Boutique hotel in historic downtown Seneca. Room#1, Q/K combo.

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Welcome to the heart of downtown Seneca, South Carolina. Formerly the Richardson Theatre in the late 50s, our building ...

    From $204 per night (USD)

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    Details
  • Lake Keowee waterfront Escape!
    From $1681 per night (USD)

    Expedia

    Lake Keowee waterfront Escape!

    Bedrooms:
    5
    Bathrooms:
    5
    Sleeps:
    18

    The Beulah House: a lake Keowee waterfront escape. 20 minutes to downtown Clemson, SC. This home has everything you need ...

    From $1681 per night (USD)

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  • Modern 3 BR home, interior lot near Lake Keowee, Clemson, Walhalla, Seneca.
    From $462 per night (USD)

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    Modern 3 BR home, interior lot near Lake Keowee, Clemson, Walhalla, Seneca.

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    New modern home 3 Bedroom 2 Bath on interior lot in a quiet neighborhood near Clemson and Lake Keowee. 2 king and 2 twin ...

    From $462 per night (USD)

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  • Mtn. Rest Cottage Laurel Suite
    From $340 per night (USD)

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    Mtn. Rest Cottage Laurel Suite

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    Escape to the beauty of the Blue Ridge Mountains and experience a peaceful getaway at our charming 2-bedroom, 1-bath mou ...

    From $340 per night (USD)

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  • Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms
    From $343 per night (USD)

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    Lakeside Clemson Condo With 4K/Surround Sound/Xbox/Coffee Bar/Private Bathrooms

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    6

    Experience the pinnacle of convenience at our exceptional condo, your ideal sanctuary for exploring the vibrant essence ...

    From $343 per night (USD)

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  • The Bark Shed Lake House with boat dock
    From $1038 per night (USD)

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    The Bark Shed Lake House with boat dock

    Bedrooms:
    4
    Bathrooms:
    5
    Sleeps:
    14

    Welcome to your dream lakeside getaway on the pristine waters of Lake Keowee! Our spacious 5-bedroom, 4-bathroom home of ...

    From $1038 per night (USD)

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  • Keowee Key Townhouse- Lake, great deck, outdoor firetable & CLEMSON FOOTBALL!
    From $294 per night (USD)

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    Keowee Key Townhouse- Lake, great deck, outdoor firetable & CLEMSON FOOTBALL!

    Bedrooms:
    2
    Bathrooms:
    4
    Sleeps:
    8

    NEW OWNER SPECIAL! - Enjoy 3 separate floors with private bedroom and bath on each floor - Lounge outside on the priva ...

    From $294 per night (USD)

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  • Pet-Friendly 5BR Getaway near Lake Keowee
    From $493 per night (USD)

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    Pet-Friendly 5BR Getaway near Lake Keowee

    Bedrooms:
    3
    Bathrooms:
    5
    Sleeps:
    14

    Welcome to Lakeside Hill @ Keowee, a spacious and pet-friendly retreat conveniently located just across the street from ...

    From $493 per night (USD)

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  • Knot On Call Lake House + HOT TUB
    From $760 per night (USD)

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    Knot On Call Lake House + HOT TUB

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    12

    Welcome to our 4-bedroom, 3 bathroom lakefront retreat on the serene shores of Lake Keowee! Located 10 minutes to Clems ...

    From $760 per night (USD)

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  • Keowee Key's Stylish Charm
    From $412 per night (USD)

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    Keowee Key's Stylish Charm

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Welcome to our charming and stylish condo in the heart of the picturesque Keowee Key community! This inviting retreat is ...

    From $412 per night (USD)

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  • Waterfront Seneca Cabin ~ 4 Mi to Boat Launch!
    From $272 per night (USD)

    VRBO

    Waterfront Seneca Cabin ~ 4 Mi to Boat Launch!

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    4

    Lake life awaits at this lovely Seneca cabin! With its rustic interior, large screened porch, and deck facing the water, ...

    From $272 per night (USD)

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  • Off the Beaten Path: Cottage for families and fisherman.
    From $233 per night (USD)

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    Off the Beaten Path: Cottage for families and fisherman.

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    8

    Renovated 2 bedroom, 2 bath home with additional 3rd loft bedroom to host both families and fisherman alike. It's ready ...

    From $233 per night (USD)

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  • Private RV Camping spot with plenty of room to stretch. Intimate and private.
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    Private RV Camping spot with plenty of room to stretch. Intimate and private.

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    6

    Private home camping location for RV or Pop up. There is room for an RV or pop up under 12' high covered carport next to ...

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  • Fun Keowee Key TownHse Golf Lake Tennis Pickleball
    From $262 per night (USD)

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    Fun Keowee Key TownHse Golf Lake Tennis Pickleball

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    6

    A lush serene setting of trees, walking paths and nature surround this 3 level townhome within the gates of Keowee Key. ...

    From $262 per night (USD)

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  • Cozy camper in Clemson Hills.  5 minutes from Clemson University.  Pet friendly!
    From $201 per night (USD)

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    Cozy camper in Clemson Hills. 5 minutes from Clemson University. Pet friendly!

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Cozy camper with everything you need. Located in Clemson Hills RV Club, you are just minutes away from Clemson Universi ...

    From $201 per night (USD)

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  • 5-bedroom vacation home with a private dock on Lake Keowee
    From $1284 per night (USD)

    Expedia

    5-bedroom vacation home with a private dock on Lake Keowee

    Bedrooms:
    5
    Bathrooms:
    5
    Sleeps:
    10

    Discover a beautiful five-bedroom getaway situated on Lake Keowee's shoreline in Seneca. Enjoy free WiFi, a cozy firepla ...

    From $1284 per night (USD)

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    Details
  • Private Lake / Hot Tub / Large Deck / Rest & Relax / Kayaks & Canoe
    From $601 per night (USD)

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    Private Lake / Hot Tub / Large Deck / Rest & Relax / Kayaks & Canoe

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    6

    The Retreat is the perfect getaway for someone who is looking to rest and relax, while also enjoying all that nature has ...

    From $601 per night (USD)

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    Details
  • Lake Jocassee Home - Incredible Dock and Mountain and Sunset Views - Devils Fork
    From $753 per night (USD)

    Expedia

    Lake Jocassee Home - Incredible Dock and Mountain and Sunset Views - Devils Fork

    Bedrooms:
    3
    Bathrooms:
    5
    Sleeps:
    10

    One of only 38 homes on lake Jocassee, the clearwater jewel of South Carolina. The lake features seven amazing waterfall ...

    From $753 per night (USD)

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  • Waterfront home with water views from the large deck and dock on deep water
    From $292 per night (USD)

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    Waterfront home with water views from the large deck and dock on deep water

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    Peaceful lakefront home with gentle slope toward the water with a large dock for your boat, sunbathing or morning coffee ...

    From $292 per night (USD)

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  • Between Clemson and Seneca, ‘Tween Two Cats, the perfect place to land.
    From $246 per night (USD)

    VRBO

    Between Clemson and Seneca, ‘Tween Two Cats, the perfect place to land.

    Bedrooms:
    1
    Bathrooms:
    3
    Sleeps:
    6

    Tucked between Clemson and Seneca, Tween Two Cats is your cozy Upstate escape—where mornings start slow on the screened ...

    From $246 per night (USD)

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  • Lake Keowee Waterfront Town Home - 3 Bdrm, 3.5 Bath 7 Miles from Clemson Stadium
    From $402 per night (USD)

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    Lake Keowee Waterfront Town Home - 3 Bdrm, 3.5 Bath 7 Miles from Clemson Stadium

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    10

    Make memories of a lifetime in this cozy, waterfront Town home on Lake Keowee. Beautiful sunset views, community pool 1 ...

    From $402 per night (USD)

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  • The Hilltop Hideaway at Lake Hartwell
    From $224 per night (USD)

    Expedia

    The Hilltop Hideaway at Lake Hartwell

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    7

    Perched atop a secluded hill, this unique treehouse offers stunning mountain and nature views in a peaceful, private set ...

    From $224 per night (USD)

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  • Country Club Life at Renovated 2BR - 2.5 Bath with Golf/Bike/Boat/Pickleball/etc
    From $200 per night (USD)

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    Country Club Life at Renovated 2BR - 2.5 Bath with Golf/Bike/Boat/Pickleball/etc

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    4

    Located in the beautiful country club community of Keowee Key. Come enjoy our hilltop unit that has custom bathrooms and ...

    From $200 per night (USD)

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  • Lake Hartwell Getaway w/ Private Dock + Fire Pit!
    From $716 per night (USD)

    Expedia

    Lake Hartwell Getaway w/ Private Dock + Fire Pit!

    Bedrooms:
    3
    Bathrooms:
    6
    Sleeps:
    14

    Ensure plenty of entertainment for the entire family when you stay at this incredible Fair Play vacation rental! With a ...

    From $716 per night (USD)

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    Details
  • Keowee's Majestic Mountain View
    From $1426 per night (USD)

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    Keowee's Majestic Mountain View

    Bedrooms:
    4
    Bathrooms:
    6
    Sleeps:
    18

    This stunning 6-bedroom, 4.5-bathroom retreat offers an expansive 6800 sq. ft. of luxury living space, ensuring a comfor ...

    From $1426 per night (USD)

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    Details
  • Clemson Barndominium -close to University and lakes
    From $216 per night (USD)

    Expedia

    Clemson Barndominium -close to University and lakes

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    6

    This is a unique, cozy space! It has an open floor plan with a huge living/dining area. The cozy kitchen has a mini co ...

    From $216 per night (USD)

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    Details
  • Foreststone Fabulous Lake Keowee Waterfront Home
    From $1503 per night (USD)

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    Foreststone Fabulous Lake Keowee Waterfront Home

    Bedrooms:
    5
    Bathrooms:
    6
    Sleeps:
    16

    Discover the ultimate lakeside retreat at Foreststone 327, a stunning waterfront home nestled on the picturesque shores ...

    From $1503 per night (USD)

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  • The Jocassee Tiny House
    From $284 per night (USD)

    Expedia

    The Jocassee Tiny House

    Bedrooms:
    1
    Bathrooms:
    3
    Sleeps:
    8

    The Jocassee Tiny House is nestled on 13 acres of land near beautiful Lake Jocassee. On the property, you will find a li ...

    From $284 per night (USD)

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  • Historic Seneca Bungalow
    From $143 per night (USD)

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    Historic Seneca Bungalow

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    4

    This location is perfect to relax with boutique shopping and eating on Ram Cat Alley in downtown Seneca only 2 blocks aw ...

    From $143 per night (USD)

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    Details
  • Longrifle Lodge
    From $157 per night (USD)

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    Longrifle Lodge

    Bedrooms:
    1
    Bathrooms:
    1
    Sleeps:
    4

    Get off the grid without going far. The river-side home offers ample yard space as well as a covered gathering area and ...

    From $157 per night (USD)

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  • Sunset Ridge Lake Front Retreat
    From $1441 per night (USD)

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    Sunset Ridge Lake Front Retreat

    Bedrooms:
    4
    Bathrooms:
    5
    Sleeps:
    16

    Welcome to Sunset Ridge 206, a stunning lakefront retreat located in the picturesque Seneca, South Carolina. This spacio ...

    From $1441 per night (USD)

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    Details
  • Massive Lake Keowee Knox Campground Cabin
    From $977 per night (USD)

    Expedia

    Massive Lake Keowee Knox Campground Cabin

    Bedrooms:
    5
    Bathrooms:
    6
    Sleeps:
    14

    Welcome to the stunning Knox Campground Cabin, nestled on the picturesque shores of Lake Keowee in Seneca, South Carolin ...

    From $977 per night (USD)

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    Details
  • Peninsula Sunset View of Keowee
    From $1097 per night (USD)

    VRBO

    Peninsula Sunset View of Keowee

    Bedrooms:
    5
    Bathrooms:
    5
    Sleeps:
    16

    Discover the breathtaking beauty of Lake Keowee at the Peninsula Sunset View of Keowee, a stunning waterfront home locat ...

    From $1097 per night (USD)

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  • Honeysuckle 208: Spacious 7-bedroom waterfront retreat in Seneca, SC.
    From $1147 per night (USD)

    Expedia

    Honeysuckle 208: Spacious 7-bedroom waterfront retreat in Seneca, SC.

    Bedrooms:
    6
    Bathrooms:
    7
    Sleeps:
    14

    Welcome to Honeysuckle 208, a stunning waterfront retreat located on the picturesque Lake Keowee in Seneca, South Caroli ...

    From $1147 per night (USD)

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    Details
  • Lake Keowee Ln - Awesome Lake Keowee Views
    From $741 per night (USD)

    VRBO

    Lake Keowee Ln - Awesome Lake Keowee Views

    Bedrooms:
    3
    Bathrooms:
    4
    Sleeps:
    8

    Discover the breathtaking beauty of Lake Keowee from this stunning waterfront home, perfectly situated in Seneca, South ...

    From $741 per night (USD)

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    Details
  • S Circle 220: A beautifully restored 2-bedroom home in charming Salem, SC.
    From $287 per night (USD)

    Expedia

    S Circle 220: A beautifully restored 2-bedroom home in charming Salem, SC.

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    4

    Welcome to S Circle 220, a beautifully restored home nestled in the charming town of Salem, South Carolina. This invitin ...

    From $287 per night (USD)

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    Details
  • Lakefront Condo Lake Keowee • Resort Amenity • Modern Luxury Vibe • Dog Friendly
    From $433 per night (USD)

    VRBO

    Lakefront Condo Lake Keowee • Resort Amenity • Modern Luxury Vibe • Dog Friendly

    Bedrooms:
    2
    Bathrooms:
    3
    Sleeps:
    6

    Your ultimate lakeside escape awaits at this high-end, 1,900-square-foot waterfront condo nestled inside the prestigious ...

    From $433 per night (USD)

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  • Little River Retreat
    From $322 per night (USD)

    Expedia

    Little River Retreat

    Bedrooms:
    2
    Bathrooms:
    2
    Sleeps:
    4

    Welcome to Little River Retreat, a charming getaway nestled in the serene surroundings of Walhalla, South Carolina. This ...

    From $322 per night (USD)

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  • Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom
    From $363 per night (USD)

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    Resort Pool & Spa 3BR 3BTH w Loft, Family Gameroom

    Bedrooms:
    3
    Bathrooms:
    3
    Sleeps:
    9

    Escape to this spacious three-story, family-friendly townhome w bedrooms, baths, and decks on each level—perfect for lar ...

    From $363 per night (USD)

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    Details
  • Cozy cottage quiet and secluded but close to everything.
    From $224 per night (USD)

    Expedia

    Cozy cottage quiet and secluded but close to everything.

    Bedrooms:
    1
    Bathrooms:
    2
    Sleeps:
    5

    This efficiency apartment has it all full kitchen with toaster oven, microwave, microwave, fridge, coffee maker and cook ...

    From $224 per night (USD)

    Expedia

    Details