Saint Charles, Missouri Vacation Rentals. Book Beach Rentals, Lake Houses, Condos, Cabins, Villas, and Homes in Saint Charles, Missouri on RentalSaver.com!

Saint Charles Rentals

From $870 per night (USD)
VRBO
🌷RARE NEW TREASURE🌷2 Homes+Outdoor Gathering Area. Two Blocks From Main St.!!!
Bedrooms:
3
Bathrooms:
5
Sleeps:
22
Recent review. "This place is a rarity in Vrbo - it’s better than than it’s described. Space is huge." Seeking a large ...
From $870 per night (USD)
VRBO
From $253 per night (USD)
Expedia
St. Charles 1860's Gem - Sleeps 6!
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
10-foot ceilings and exposed brick walls! Brand new bath & a full kitchen for homemade meals! Plenty of natural light, s ...
From $253 per night (USD)
Expedia
From $345 per night (USD)
VRBO
Spacious home in Historic St. Charles, Near Main Street + self-serve breakfast
Bedrooms:
1
Bathrooms:
3
Sleeps:
6
Welcome to Clark Corner Guest House - the perfect place for your vacation! Enjoy the small town feel of downtown St. Ch ...
From $345 per night (USD)
VRBO
Click For Pricing
Expedia
Clark Brick House w/ Pool - Historic St. Charles
Bedrooms:
3
Bathrooms:
3
Sleeps:
10
The Clark Brick House is a spacious (2700 sq/ft), modern, and fun place for your visit to St. Charles. The house offers ...
Click For Pricing
Expedia
From $333 per night (USD)
VRBO
😉St. Charles Central Oasis-Large
Bedrooms:
2
Bathrooms:
3
Sleeps:
20
Welcome to your cozy yet large home that is perfect for any size group. When we say the house is stocked, it is fully lo ...
From $333 per night (USD)
VRBO
From $162 per night (USD)
Expedia
Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
Bedrooms:
1
Bathrooms:
3
Sleeps:
6
Our cozy home is only 8 blocks from historic Main Street. Is easily accessible from the highlights of St. Charles. Main ...
From $162 per night (USD)
Expedia
From $198 per night (USD)
VRBO
Sweet Escape Near Historic Main Street & MO River
Bedrooms:
1
Bathrooms:
4
Sleeps:
8
Discover your Sweet Escape in this charming 4-bedroom bungalow, just a 3-minute drive (or 20-minute walk) to Historic Ma ...
From $198 per night (USD)
VRBO
From $170 per night (USD)
Expedia
Residence on the Roundabout
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
New Listing. 1940's Brick Residence in Historic Frenchtown Neighborhood. Whole house with 2 Bedrooms King Bed in each. ...
From $170 per night (USD)
Expedia
From $222 per night (USD)
VRBO
Amazing Renovated Historic Loft on Main Street
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
Historic loft centrally located along the St. Charles riverfront, on the north end of Main Street and just south of Fren ...
From $222 per night (USD)
VRBO
From $222 per night (USD)
Expedia
Main Street Balcony Apartment by StayLage!
Bedrooms:
3
Bathrooms:
2
Sleeps:
6
Upstairs Main Street apartment that can host up to 5 guests. With a full parade balcony with lounge seating to sit back, ...
From $222 per night (USD)
Expedia
From $215 per night (USD)
VRBO
The Original Custom House!
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
Come stay in what was St. Charles original Customs House built in 1801, but fully stocked with modern amenities and comf ...
From $215 per night (USD)
VRBO
From $349 per night (USD)
Expedia
UPSCALE HISTORIC MAIN ST*Huge Dining, Kitchen,Fenced BckYrd. PETS/Handicap acces
Bedrooms:
2
Bathrooms:
3
Sleeps:
9
This unique luxurious 1650 sqft open floor plan entire home is unlike any other home in the St. Charles area. Newly Remo ...
From $349 per night (USD)
Expedia
From $143 per night (USD)
VRBO
Charming Duplex on Main
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
This charming 1 bedroom- 1 bathroom Duplex is the Perfect Haven for a Weekend Getaway or a productive business trip! Ne ...
From $143 per night (USD)
VRBO
From $160 per night (USD)
Expedia
Duplex Hideaway in St. Charles, MO
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
This perfectly located ONE bedroom, ONE bathroom duplex is an ideal retreat for a weekend escape or a productive busines ...
From $160 per night (USD)
Expedia
From $155 per night (USD)
VRBO
Historic Main Street Heritage Retreat
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
Come enjoy the perfect Main Street spot. Directly above popular shops and restaurants, night scene (Please note this uni ...
From $155 per night (USD)
VRBO
From $218 per night (USD)
Expedia
Cozy Front Lake Home in Newtown St. Charles
Bedrooms:
2
Bathrooms:
4
Sleeps:
8
Nestled in the heart of New Town St. Charles, our cozy home offers a perfect blend of comfort, style, and convenience fo ...
From $218 per night (USD)
Expedia
From $348 per night (USD)
VRBO
Luxurious, spa-like retreat steps from Main St.
Bedrooms:
2
Bathrooms:
1
Sleeps:
2
When French Canadian fur trader Louis Blanchette arrived in 1769 in what we now know as St. Charles, he saw the beautifu ...
From $348 per night (USD)
VRBO
From $145 per night (USD)
Expedia
The Owl Suite at Divine Otter
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Wisdom and elegance define our accessible Owl Suite, the second largest accommodation in our collection. This thoughtful ...
From $145 per night (USD)
Expedia
From $247 per night (USD)
VRBO
5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
This Gem is fully renovated with everything you should need in the Historic District. The Katy Trail is just a 2 minute ...
From $247 per night (USD)
VRBO
From $258 per night (USD)
Expedia
Luxurious couples retreat just steps from Historic Main Street in St. Charles!
Bedrooms:
1
Bathrooms:
1
Sleeps:
3
The Lewis & Clark Guest House is a historic cottage that has been thoughtfully remodeled into a luxurious retreat while ...
From $258 per night (USD)
Expedia
From $327 per night (USD)
VRBO
Minutes from Main Street - Updated House w/ 4 Patios, Private Parking & Trolley
Bedrooms:
1
Bathrooms:
3
Sleeps:
8
Located in the heart of Frenchtown, is this beautifully updated home that sleeps 8. This is a must see!!! From the custo ...
From $327 per night (USD)
VRBO
From $274 per night (USD)
Expedia
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
Bedrooms:
2
Bathrooms:
3
Sleeps:
7
The Old Town Guest House is an upscale vacation home originally built in 1870 and beautifully renovated with tasteful an ...
From $274 per night (USD)
Expedia
From $275 per night (USD)
VRBO
The St. Charles Guest House, lovely historic home, fun for families and groups
Bedrooms:
2
Bathrooms:
3
Sleeps:
8
"The St. Charles Guest House" is a beautifully renovated and decorated home in the heart of Historic St. Charles, MO. Th ...
From $275 per night (USD)
VRBO
From $259 per night (USD)
Expedia
1790's Renovated Barn, Main Street St. Charles, Hot Tub in private backyard!
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
The Red Barn Guest House is a beautifully remodeled home with amazing details that makes this vacation rental truly uniq ...
From $259 per night (USD)
Expedia
From $151 per night (USD)
VRBO
Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
A cozy single-family home in the heart of Frenchtown in Saint Charles, MO right around the corner from Historic Main Str ...
From $151 per night (USD)
VRBO
From $153 per night (USD)
Expedia
Spacious 2 bed Townhome by StayLage
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
2 bedroom, 1.5 bath townhome available within walking distance of Streets of Saint Charles. Just south of I-70 Enjoy thi ...
From $153 per night (USD)
Expedia
From $352 per night (USD)
VRBO
Walking distance to Historic Main Street, St. Charles, MO
Bedrooms:
3
Bathrooms:
3
Sleeps:
6
Welcome to your home away from home! This cozy 3-bedroom, 3-bathroom house is the perfect retreat for your stay in St. C ...
From $352 per night (USD)
VRBO
From $281 per night (USD)
Expedia
Honky Tonk Hideaway
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
Welcome to the Honky Tonk Hideaway nestled near the historic charm of Main Street in Saint Charles! This inviting house ...
From $281 per night (USD)
Expedia
From $172 per night (USD)
VRBO
The Wild West Getaway- 204-1
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
Welcome to Cowboy, our charming, 2 bedroom/1 bathroom apartment located in the heart of historic St. Charles. Saddle up ...
From $172 per night (USD)
VRBO
From $238 per night (USD)
VRBO
Spacious Historic Townhouse - Character for All
Bedrooms:
2
Bathrooms:
2
Sleeps:
8
This charming spacious historic townhouse is a completely renovated century-old duplex, near Historic Old Town St. Charl ...
From $238 per night (USD)
VRBO
From $138 per night (USD)
VRBO
Private Basement - Two King Beds and Hot Tub
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Welcome to our private and cozy basement retreat with a Hot Tub! Our beautifully furnished basement unit is perfect for ...
From $138 per night (USD)
VRBO
From $199 per night (USD)
Expedia
The Maison Champignon
Bedrooms:
1
Bathrooms:
3
Sleeps:
6
The space Maison Champignon is a charming 3BR/1BA getaway with a warm French-Country feel, nestled in the heart of St. ...
From $199 per night (USD)
Expedia
From $188 per night (USD)
VRBO
Adorable 2 King Bed Frenchtown Home
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
You are going to love this stylish and well decorated home in St Charles. Well Stocked with all the amenities you will n ...
From $188 per night (USD)
VRBO
From $178 per night (USD)
Expedia
Charming Historic Retreat in Old Town St. Charles
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Experience the charm of Old Town St. Charles in this cozy and beautifully restored home. Just steps from local shops, di ...
From $178 per night (USD)
Expedia
From $149 per night (USD)
VRBO
Cozy Unit on Historic Main Street
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
ON MAIN ST NEAR EVERYTHING Discover your perfect getaway in charming St. Charles, right on historic Main Street! This i ...
From $149 per night (USD)
VRBO
From $133 per night (USD)
Expedia
Spacious Cottage on Main st- Near Downtown
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
MESSAGE FOR DISCOUNT ON SHORT STAY Welcome to our charming 2-bedroom, 1-bathroom unit on historic Main St. in the heart ...
From $133 per night (USD)
Expedia
From $198 per night (USD)
VRBO
Peaceful & Cozy Stay
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Escape to tranquility just 1.1 mi from New Town St. Charles. Our home harmonizes convenience with comfort—3 beds, 2.5 ba ...
From $198 per night (USD)
VRBO
From $229 per night (USD)
VRBO
Charming 2-Bed Brownstone in The Heart of New Town
Bedrooms:
2
Bathrooms:
2
Sleeps:
4
Our home is in the heart of New Town, just steps away from the coffee shop & restaurants! It's within 5 miles of histor ...
From $229 per night (USD)
VRBO
From $346 per night (USD)
VRBO
Charming open 4bd and screen-in porch! Sleeps 10!
Bedrooms:
2
Bathrooms:
4
Sleeps:
10
Minutes from LU, Mainstreet, Streets of St Charles & Ameristar! This beautiful home in a quiet neighborhood is central t ...
From $346 per night (USD)
VRBO
From $409 per night (USD)
Expedia
Charming 4BR near Convention Ctr., Main St, & LU -just 11 minutes to STL Airport
Bedrooms:
2
Bathrooms:
4
Sleeps:
8
St. Charles is known for its historic architecture, specialty stores and antiques, lovely parks, and various recreation ...
From $409 per night (USD)
Expedia
From $461 per night (USD)
VRBO
The Wild Rose Cottage in Historic Old St Charles
Bedrooms:
4
Bathrooms:
4
Sleeps:
12
Introducing The Wild Rose Cottage! This brand new beauty abounds with space and "Glam Cottage" charm. It is perfectly lo ...
From $461 per night (USD)
VRBO
From $306 per night (USD)
VRBO
Dreamy St Charles Retreat w/ Furnished Patio!
Bedrooms:
2
Bathrooms:
3
Sleeps:
8
Gain access to the beauty of St. Charles when you stay at this historic vacation rental! A part of the National Historic ...
From $306 per night (USD)
VRBO
From $289 per night (USD)
VRBO
Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway
Bedrooms:
1
Bathrooms:
3
Sleeps:
10
**We are AirBandB Superhosts for 3 years running! Over 200, 5 Star Reviews!** The Blue Oak is nestled in the center of ...
From $289 per night (USD)
VRBO
From $346 per night (USD)
Expedia
Spacious, Beautiful St. Charles Home-Remodeled-Sleeps 10! New Patio!
Bedrooms:
2
Bathrooms:
3
Sleeps:
12
Bring the whole family to this great place with lots of room for fun. Centrally located in downtown St. Charles - walkin ...
From $346 per night (USD)
Expedia
From $343 per night (USD)
VRBO
Home Near Main Street-Covered Patio-Hot Tub!
Bedrooms:
2
Bathrooms:
3
Sleeps:
12
Have fun with the whole family at this stylish Home! Brand new everything! Upscale kitchen for making meals, 2 full bath ...
From $343 per night (USD)
VRBO
From $286 per night (USD)
Expedia
Walk to St Charles Main St. Shops, Eateries & Bars!
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
The "Lion House" is a completely restored charming 1930s home located in the heart of St. Charles’ National Historic Dis ...
From $286 per night (USD)
Expedia
From $416 per night (USD)
VRBO
BEAUTIFUL Historic 3 Bedroom Upscale Guesthouse!!
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Spacious luxury three bedroom home in historic St. Charles. Minutes away from Main Street, French town, Streets of St. C ...
From $416 per night (USD)
VRBO
From $345 per night (USD)
Expedia
New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!
Bedrooms:
2
Bathrooms:
3
Sleeps:
12
*Recently remodeled* beautiful 3 bed, 2 full bath home that offers more than 1,600 SF. The natural light and open floor ...
From $345 per night (USD)
Expedia
From $398 per night (USD)
VRBO
Saint Charles House Near Historic Downtown!
Bedrooms:
3
Bathrooms:
4
Sleeps:
9
Explore the St. Louis area from this vacation rental in Saint Charles, MO! Just 6 miles from the city’s historic downtow ...
From $398 per night (USD)
VRBO
From $176 per night (USD)
Expedia
Charming Home in Cozy Frenchtown Saint Charles
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
Welcome to your perfect getaway nestled in the heart of Frenchtown, Saint Charles! This spacious home combines historic ...
From $176 per night (USD)
Expedia
From $471 per night (USD)
VRBO
FALL SALE NOW | Private |Game Rm | Hot Tub | .67 acres |
Bedrooms:
4
Bathrooms:
4
Sleeps:
14
🌸 **FALL Sale Now On!** 🌸 Experience our hand crafted vacation rental featuring a modern kitchen with updated app ...
From $471 per night (USD)
VRBO

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Saint Charles Rentals

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Results: 51 Rentals