Seneca, South Carolina Vacation Rentals. Book Beach Rentals, Lake Houses, Condos, Cabins, Villas, and Homes in Seneca, South Carolina on RentalSaver.com!

Seneca Rentals

From $346 per night (USD)
VRBO
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson!
Bedrooms:
1
Bathrooms:
3
Sleeps:
8
Step back in time in this renovated 1940 historic bungalow in downtown Seneca, SC. This charming 3BR, 1.5BA home sleeps ...
From $346 per night (USD)
VRBO
From $337 per night (USD)
Expedia
7 Mi to Clemson Stadiums: Lake Keowee Getaway!
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
Loran Pointe | Lake-View Deck w/ Fire Pit | Community Pool | Near Restaurants & Shops This 2-bedroom, 2-bath vacation r ...
From $337 per night (USD)
Expedia
From $425 per night (USD)
VRBO
Tee House on BEAUTIFUL Lake Keowee
Bedrooms:
4
Bathrooms:
4
Sleeps:
8
Waterfront on beautiful Lake Keowee.. Only minutes to Clemson Death Valley for all the college sports.. Take a short wal ...
From $425 per night (USD)
VRBO
From $312 per night (USD)
Expedia
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock
Bedrooms:
2
Bathrooms:
4
Sleeps:
8
This cozy 4 Br cottage has all the amenities of home and feels just as comfortable. With over 16 feet of sliding doors ...
From $312 per night (USD)
Expedia
From $619 per night (USD)
VRBO
Comfortably Designed Lake Keowee Waterfront, Minutes to Clemson- In Seneca
Bedrooms:
4
Bathrooms:
5
Sleeps:
10
Enjoy this like newly renovated retreat on Lake Keowee. Comfortably designed and professionally decorated by Trio Inter ...
From $619 per night (USD)
VRBO
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Expedia
Lakefront Keowee with Private Dock and Huge Patio! Kayaks, Grill+ Outdoor TV
Bedrooms:
3
Bathrooms:
5
Sleeps:
12
Just off Hwy 123, minutes from downtown Seneca and less than 15 minutes from Clemson. Our modern open layout farmhouse ...
Click For Pricing
Expedia
From $632 per night (USD)
VRBO
New! The Tiger's Perch- Close to Clemson.
Bedrooms:
2
Bathrooms:
4
Sleeps:
8
🛏 4 Comfortable Bedrooms – Thoughtfully decorated with cozy bedding and ample storage. 🛁 2 Full Bathrooms – Clean, upd ...
From $632 per night (USD)
VRBO
From $665 per night (USD)
Expedia
The Big Golf House- 10 miles to Clemson
Bedrooms:
4
Bathrooms:
4
Sleeps:
8
Welcome to your spacious golf course retreat in Seneca, South Carolina, just 15 minutes from Clemson University and minu ...
From $665 per night (USD)
Expedia
From $533 per night (USD)
VRBO
Lake Keowee: Lake front 7 mi from Clemson stadium
Bedrooms:
3
Bathrooms:
3
Sleeps:
10
Comfortable, newly remodeled open plan house on Lake Keowee- south end -10 minute drive from Clemson's Death Valley or a ...
From $533 per night (USD)
VRBO
From $393 per night (USD)
Expedia
Lake Keowee Waterfront Town Home - 3 Bdrm, 3.5 Bath 7 Miles from Clemson Stadium
Bedrooms:
3
Bathrooms:
3
Sleeps:
10
Make memories of a lifetime in this cozy, waterfront Town home on Lake Keowee. Beautiful sunset views, community pool 1 ...
From $393 per night (USD)
Expedia
From $234 per night (USD)
VRBO
Boutique hotel in historic downtown Seneca. Room #2 Owners Suite. Q/K combo.
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Welcome to the heart of downtown Seneca, South Carolina. Formerly the Richardson Theatre in the late 50s, our building ...
From $234 per night (USD)
VRBO
From $209 per night (USD)
Expedia
Boutique hotel in historic downtown Seneca. Room #4, King bed.
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Welcome to the heart of downtown Seneca, South Carolina. Formerly the Richardson Theatre in the late 50s, our building ...
From $209 per night (USD)
Expedia
From $160 per night (USD)
VRBO
Private Room #3
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Welcome to the heart of downtown Seneca, South Carolina. Formerly the Richardson Theatre in the late 50s, our building ...
From $160 per night (USD)
VRBO
From $150 per night (USD)
Expedia
Boutique hotel in historic downtown Seneca. Room #6, King Bed.
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Welcome to the heart of downtown Seneca, South Carolina. Formerly the Richardson Theatre in the late 50s, our building ...
From $150 per night (USD)
Expedia
From $158 per night (USD)
VRBO
Boutique hotel in historic downtown Seneca. Room #5, two King beds.
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Welcome to the heart of downtown Seneca, South Carolina. Formerly the Richardson Theatre in the late 50s, our building ...
From $158 per night (USD)
VRBO
From $209 per night (USD)
Expedia
Boutique hotel in historic downtown Seneca. Room#1, Q/K combo.
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Welcome to the heart of downtown Seneca, South Carolina. Formerly the Richardson Theatre in the late 50s, our building ...
From $209 per night (USD)
Expedia
From $1034 per night (USD)
VRBO
Knot On Call Lake House + HOT TUB
Bedrooms:
3
Bathrooms:
4
Sleeps:
12
Welcome to our 4-bedroom, 3 bathroom lakefront retreat on the serene shores of Lake Keowee! Located 10 minutes to Clems ...
From $1034 per night (USD)
VRBO
From $201 per night (USD)
VRBO
Bisquini Point at Lake Keowee
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Enjoy relaxing and soaking up the beautiful Lake Keowee from this home. Located minutes from a grocery store and restau ...
From $201 per night (USD)
VRBO
From $250 per night (USD)
VRBO
Keowee Adventures ~ Peaceful Lakefront Home on Keowee ~ 7 Miles from Clemson!
Bedrooms:
3
Bathrooms:
3
Sleeps:
8
Escape to a lakeside retreat just 5 minutes from downtown Seneca. Our 3-bedroom, 3-bathroom home offers the perfect plac ...
From $250 per night (USD)
VRBO
From $135 per night (USD)
Expedia
Historic Seneca Bungalow
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
This location is perfect to relax with boutique shopping and eating on Ram Cat Alley in downtown Seneca only 2 blocks aw ...
From $135 per night (USD)
Expedia
From $898 per night (USD)
VRBO
Inlet Lake Keowee Home Close to Clemson
Bedrooms:
4
Bathrooms:
4
Sleeps:
10
Summary: Just 10 minutes from Clemson The gorgeous hardwood floors give the main living room and kitchen area a warm gl ...
From $898 per night (USD)
VRBO
From $116 per night (USD)
Expedia
Beautiful home near Clemson
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
Convenient to anywhere you would like to be in our area. Less than a mile from shops, restaurants, breweries, Jazz on th ...
From $116 per night (USD)
Expedia
From $580 per night (USD)
VRBO
Pirate's Retreat -Beautifully renovated lake home with Dock minutes from Clemson
Bedrooms:
2
Bathrooms:
3
Sleeps:
8
Enjoy a relaxing stay on the water. Beautiful 3 bedroom, 2 bath home with everything from new appliances and furniture ...
From $580 per night (USD)
VRBO
From $523 per night (USD)
Expedia
Lake Keowee Home w/ Boat Dock in Seneca
Bedrooms:
2
Bathrooms:
3
Sleeps:
8
Near Keowee Marina | Peaceful Location | Outdoor Smart TV Experience the tranquility of this 3-bedroom, 2-bath vacation ...
From $523 per night (USD)
Expedia
From $296 per night (USD)
VRBO
Keoweenie Lake Side Cottage
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
This Seneca house boasts 2 inviting bedrooms with 1 queen bed and 1 king bed. The bathroom comes equipped with a hair dr ...
From $296 per night (USD)
VRBO
From $715 per night (USD)
Expedia
Beautiful Home on Lake Keowee- Deep Water Dock- 4bd/4ba -Close to Clemson
Bedrooms:
4
Bathrooms:
4
Sleeps:
15
Our home is situated on a quiet cul-de-sac that shares a point at the south end of Lake Keowee with a panoramic view of ...
From $715 per night (USD)
Expedia
From $190 per night (USD)
VRBO
Lake Keowee Condo with Great Views! Near Clemson, Marina, Hiking, Waterfalls!
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
BIG MONTHLY DISCOUNT! 2 bedroom 2.5 bath condo with a small loft located in the town of Seneca SC. Views of beautiful La ...
From $190 per night (USD)
VRBO
From $1151 per night (USD)
Expedia
Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson.
Bedrooms:
3
Bathrooms:
5
Sleeps:
18
A perfect lake front get-away on Lake Keowee in Seneca South Carolina! Relax by the pool overlooking the lake, or on the ...
From $1151 per night (USD)
Expedia
$Enjoy Paradise on Lake Keowee\n$
From $883 per night (USD)
VRBO
Enjoy Paradise on Lake Keowee\n
Bedrooms:
3
Bathrooms:
4
Sleeps:
7
* I have enlarged and covered the back deck and added an outdoor kitchen. Renovated lake home overlooking the very be ...
From $883 per night (USD)
VRBO
$Seneca Serenity. Huge Lake Front House. \n$
From $1177 per night (USD)
Expedia
Seneca Serenity. Huge Lake Front House. \n
Bedrooms:
5
Bathrooms:
7
Sleeps:
24
Beautiful two-story family-friendly home. We are located on a large secluded lot on Lake Keowee without neighbors on eit ...
From $1177 per night (USD)
Expedia
From $221 per night (USD)
VRBO
Cozy 3 bed/2bath home near Clemson
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Our home is small but cozy 3 bed/2 bath home with an open floor plan. The master suite has a private bathroom and is sep ...
From $221 per night (USD)
VRBO
From $897 per night (USD)
VRBO
Secluded Lake Front Keowee Home In-Town on over 2 acres with Private Dock
Bedrooms:
3
Bathrooms:
6
Sleeps:
16
This stunning lake front home is an outdoor enthusiast’s dream. Enjoy over 2 Acres of privacy in this unassuming 6 bedro ...
From $897 per night (USD)
VRBO
From $618 per night (USD)
VRBO
Stunning Seneca Home w/ Lake Keowee Access!
Bedrooms:
2
Bathrooms:
4
Sleeps:
10
With the shoreline just steps away and endless waterfront activities at your fingertips, this 4-bedroom, 2.5-bath vacati ...
From $618 per night (USD)
VRBO
From $369 per night (USD)
VRBO
Palmetto Paradise Houseboat
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
Palmetto Paradise Houseboat rental at Keowee Marina is a true hidden gem located on beautiful Lake Keowee. This 75' hous ...
From $369 per night (USD)
VRBO
From $494 per night (USD)
VRBO
Lakefront Keowee Luxury Cottages 127
Bedrooms:
3
Bathrooms:
3
Sleeps:
8
Located on beautiful Lake Keowee in Seneca SC and only 10 minutes from downtown Clemson. This new luxury cottage allows ...
From $494 per night (USD)
VRBO
From $505 per night (USD)
VRBO
Lakefront Keowee Luxury Cottages 129
Bedrooms:
3
Bathrooms:
3
Sleeps:
8
Located on beautiful Lake Keowee in Seneca SC and only 10 minutes from downtown Clemson. This new luxury cottage allows ...
From $505 per night (USD)
VRBO
From $998 per night (USD)
VRBO
Lakefront Spacious Home w/dock
Bedrooms:
3
Bathrooms:
6
Sleeps:
17
Welcome to Chartwell Point, located on the South end of Lake Keowee! Enjoy the quiet deep-water cove great for sunning ...
From $998 per night (USD)
VRBO
From $238 per night (USD)
Expedia
Nicely appointed 3 bedroom house located in Seneca SC near Clemson University.
Bedrooms:
1
Bathrooms:
3
Sleeps:
8
Nicely appointed 3 bedroom cottage conveniently located between Clemson and Seneca. Nestled on a quiet cul-de-sac just m ...
From $238 per night (USD)
Expedia
From $162 per night (USD)
VRBO
Tiny House/w outdoor cast-iron shower/tub
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Romantic Tiny house Get away or bring the kids! Enjoy a soak in the outdoor cast-iron tub with beautiful sunsets over th ...
From $162 per night (USD)
VRBO
From $716 per night (USD)
Expedia
Lake Keowee Ln - Awesome Lake Keowee Views
Bedrooms:
3
Bathrooms:
4
Sleeps:
8
Summary: Conveniently located at the south end of Lake Keowee this house boasts upstairs, downstairs and outdoor gatheri ...
From $716 per night (USD)
Expedia
From $1363 per night (USD)
VRBO
Keowee's Majestic Mountain View
Bedrooms:
4
Bathrooms:
6
Sleeps:
18
This stunning 6-bedroom, 4.5-bathroom retreat offers an expansive 6800 sq. ft. of luxury living space, ensuring a comfor ...
From $1363 per night (USD)
VRBO
From $326 per night (USD)
Expedia
Seneca Vacation Rental < 1 to Lake Keowee Access!
Bedrooms:
2
Bathrooms:
3
Sleeps:
8
Surrounded by towering trees and boasting a central location less than a mile away from Lake Keowee, this 3-bedroom, 2.5 ...
From $326 per night (USD)
Expedia
From $737 per night (USD)
VRBO
Newly Updated Lake Keowee Property, just 10 miles from Clemson University
Bedrooms:
3
Bathrooms:
5
Sleeps:
18
Welcome to this newly renovated lakefront retreat, nestled on the south end of picturesque Lake Keowee. This stunning ho ...
From $737 per night (USD)
VRBO
From $523 per night (USD)
Expedia
NEW! Beautiful 5 bedroom Lake Keowee Cove Home!
Bedrooms:
2
Bathrooms:
5
Sleeps:
10
Welcome to our stunning 5-bedroom home with a cove view of beautiful Lake Keowee! Nestled in a quiet cove, this spacious ...
From $523 per night (USD)
Expedia
From $258 per night (USD)
VRBO
Stay in Seneca 8 mins from Clemson Stadium: Fall Promo: Long Weekends 3/4 days.
Bedrooms:
1
Bathrooms:
3
Sleeps:
6
Fall Promo! Discount for Long Weekends, 3-4 day stays. Early check-in available. Snuggled between the home of the Clem ...
From $258 per night (USD)
VRBO
From $337 per night (USD)
Expedia
3-bedroom 2 bath home located minutes from Keowee Mariana, shopping and Clemson
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
The Landing Spot is your Lake Keowee getaway—just a short walk to the marina with boat rentals, a lakeside restaurant, b ...
From $337 per night (USD)
Expedia

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Seneca Rentals

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Results: 46 Rentals