Saint Charles Area, Missouri Vacation Rentals. Book Beach Rentals, Lake Houses, Condos, Cabins, Villas, and Homes in Saint Charles Area, Missouri on RentalSaver.com!

Saint Charles Area Rentals

From $870 per night (USD)
VRBO
🌷RARE NEW TREASURE🌷2 Homes+Outdoor Gathering Area. Two Blocks From Main St.!!!
Bedrooms:
3
Bathrooms:
5
Sleeps:
22
Recent review. "This place is a rarity in Vrbo - it’s better than than it’s described. Space is huge." Seeking a large ...
From $870 per night (USD)
VRBO
From $253 per night (USD)
Expedia
St. Charles 1860's Gem - Sleeps 6!
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
10-foot ceilings and exposed brick walls! Brand new bath & a full kitchen for homemade meals! Plenty of natural light, s ...
From $253 per night (USD)
Expedia
From $345 per night (USD)
VRBO
Spacious home in Historic St. Charles, Near Main Street + self-serve breakfast
Bedrooms:
1
Bathrooms:
3
Sleeps:
6
Welcome to Clark Corner Guest House - the perfect place for your vacation! Enjoy the small town feel of downtown St. Ch ...
From $345 per night (USD)
VRBO
From $273 per night (USD)
Expedia
Spacious*Outdoor Space*Modern*Family*Groups*Modern*Artistic
Bedrooms:
2
Bathrooms:
4
Sleeps:
13
Enjoy a stylish experience at this super conveniently-located home in the St. Louis suburbs! This unique and private 4 b ...
From $273 per night (USD)
Expedia
Click For Pricing
VRBO
Clark Brick House w/ Pool - Historic St. Charles
Bedrooms:
3
Bathrooms:
3
Sleeps:
10
The Clark Brick House is a spacious (2700 sq/ft), modern, and fun place for your visit to St. Charles. The house offers ...
Click For Pricing
VRBO
From $333 per night (USD)
Expedia
😉St. Charles Central Oasis-Large
Bedrooms:
2
Bathrooms:
3
Sleeps:
20
Welcome to your cozy yet large home that is perfect for any size group. When we say the house is stocked, it is fully lo ...
From $333 per night (USD)
Expedia
From $162 per night (USD)
VRBO
Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
Bedrooms:
1
Bathrooms:
3
Sleeps:
6
Our cozy home is only 8 blocks from historic Main Street. Is easily accessible from the highlights of St. Charles. Main ...
From $162 per night (USD)
VRBO
From $198 per night (USD)
Expedia
Sweet Escape Near Historic Main Street & MO River
Bedrooms:
1
Bathrooms:
4
Sleeps:
8
Discover your Sweet Escape in this charming 4-bedroom bungalow, just a 3-minute drive (or 20-minute walk) to Historic Ma ...
From $198 per night (USD)
Expedia
From $170 per night (USD)
VRBO
Residence on the Roundabout
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
New Listing. 1940's Brick Residence in Historic Frenchtown Neighborhood. Whole house with 2 Bedrooms King Bed in each. ...
From $170 per night (USD)
VRBO
From $237 per night (USD)
Expedia
Private St Peters Home Patio Pool Table
Bedrooms:
2
Bathrooms:
4
Sleeps:
10
Located in a quiet neighborhood and just a short drive to Busch Stadium, St.Louis Science Center, City Museum, Botanical ...
From $237 per night (USD)
Expedia
From $514 per night (USD)
VRBO
Fairway Haven at The Falls – Golf, Shops, Dining! 10-12 Mins. Equestrian Center
Bedrooms:
3
Bathrooms:
4
Sleeps:
8
Charming Two-Story Retreat with Luxury Living, Scenic Golf Views & Global Flair Discover elegance and international cha ...
From $514 per night (USD)
VRBO
From $222 per night (USD)
Expedia
Amazing Renovated Historic Loft on Main Street
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
Historic loft centrally located along the St. Charles riverfront, on the north end of Main Street and just south of Fren ...
From $222 per night (USD)
Expedia
From $222 per night (USD)
VRBO
Main Street Balcony Apartment by StayLage!
Bedrooms:
3
Bathrooms:
2
Sleeps:
6
Upstairs Main Street apartment that can host up to 5 guests. With a full parade balcony with lounge seating to sit back, ...
From $222 per night (USD)
VRBO
From $215 per night (USD)
Expedia
The Original Custom House!
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
Come stay in what was St. Charles original Customs House built in 1801, but fully stocked with modern amenities and comf ...
From $215 per night (USD)
Expedia
From $349 per night (USD)
VRBO
UPSCALE HISTORIC MAIN ST*Huge Dining, Kitchen,Fenced BckYrd. PETS/Handicap acces
Bedrooms:
2
Bathrooms:
3
Sleeps:
9
This unique luxurious 1650 sqft open floor plan entire home is unlike any other home in the St. Charles area. Newly Remo ...
From $349 per night (USD)
VRBO
From $143 per night (USD)
Expedia
Charming Duplex on Main
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
This charming 1 bedroom- 1 bathroom Duplex is the Perfect Haven for a Weekend Getaway or a productive business trip! Ne ...
From $143 per night (USD)
Expedia
From $417 per night (USD)
VRBO
Cozy Retreat Historic St. Peters
Bedrooms:
1
Bathrooms:
3
Sleeps:
6
Experience the allure of Old Town St. Peters in our charming 3-bedroom home. Nestled in a historic neighborhood, our coz ...
From $417 per night (USD)
VRBO
From $160 per night (USD)
Expedia
Duplex Hideaway in St. Charles, MO
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
This perfectly located ONE bedroom, ONE bathroom duplex is an ideal retreat for a weekend escape or a productive busines ...
From $160 per night (USD)
Expedia
From $218 per night (USD)
VRBO
WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
Welcome to the quiet magical town of Augusta, enjoy the comforts of home with 2 bedrooms, ample living space, fully stoc ...
From $218 per night (USD)
VRBO
From $155 per night (USD)
Expedia
Historic Main Street Heritage Retreat
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
Come enjoy the perfect Main Street spot. Directly above popular shops and restaurants, night scene (Please note this uni ...
From $155 per night (USD)
Expedia
From $218 per night (USD)
VRBO
Cozy Front Lake Home in Newtown St. Charles
Bedrooms:
2
Bathrooms:
4
Sleeps:
8
Nestled in the heart of New Town St. Charles, our cozy home offers a perfect blend of comfort, style, and convenience fo ...
From $218 per night (USD)
VRBO
From $244 per night (USD)
VRBO
'The Cabernet Cabin' Defiance Home on Katy Trail!
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
A quaint country escape awaits at 'Cabernet Cabin' in Defiance, MO! Ideally suited for couples and families, this 2-bedr ...
From $244 per night (USD)
VRBO
From $225 per night (USD)
VRBO
Serene Ivory*Fireplace*Fenced Yard* Dogs Welcome!
Bedrooms:
2
Bathrooms:
4
Sleeps:
8
Welcome to our humble family home Serene Ivory*Fireplace*Fenced Yard* Dogs Welcome! in O'Fallon, Missouri! Unwind on th ...
From $225 per night (USD)
VRBO
From $212 per night (USD)
Expedia
Adorable Augusta Cabin
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Located in the heart of Augusta, This small cabin makes the perfect retreat for an intimate overnight or weekend staycat ...
From $212 per night (USD)
Expedia
From $348 per night (USD)
VRBO
Luxurious, spa-like retreat steps from Main St.
Bedrooms:
2
Bathrooms:
1
Sleeps:
2
When French Canadian fur trader Louis Blanchette arrived in 1769 in what we now know as St. Charles, he saw the beautifu ...
From $348 per night (USD)
VRBO
From $386 per night (USD)
Expedia
Family Friendly Lake Front retreat with Lake Front Beach and Dock.
Bedrooms:
3
Bathrooms:
5
Sleeps:
10
Stay comfortably in our 5 bedroom 4400 sq ft Ranch home, 3.5 acre lake front estate in Lake St Louis. A short 2 min walk ...
From $386 per night (USD)
Expedia
From $145 per night (USD)
VRBO
The Owl Suite at Divine Otter
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
Wisdom and elegance define our accessible Owl Suite, the second largest accommodation in our collection. This thoughtful ...
From $145 per night (USD)
VRBO
From $247 per night (USD)
Expedia
5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
This Gem is fully renovated with everything you should need in the Historic District. The Katy Trail is just a 2 minute ...
From $247 per night (USD)
Expedia
From $234 per night (USD)
VRBO
Get away from it all
Bedrooms:
4
Bathrooms:
3
Sleeps:
6
This is a beautiful home in the middle of 90+ acres of valleys, rolling hills, operational pumpkin and hops farm with lo ...
From $234 per night (USD)
VRBO
From $327 per night (USD)
VRBO
Minutes from Main Street - Updated House w/ 4 Patios, Private Parking & Trolley
Bedrooms:
1
Bathrooms:
3
Sleeps:
8
Located in the heart of Frenchtown, is this beautifully updated home that sleeps 8. This is a must see!!! From the custo ...
From $327 per night (USD)
VRBO
From $258 per night (USD)
VRBO
Luxurious couples retreat just steps from Historic Main Street in St. Charles!
Bedrooms:
1
Bathrooms:
1
Sleeps:
3
The Lewis & Clark Guest House is a historic cottage that has been thoughtfully remodeled into a luxurious retreat while ...
From $258 per night (USD)
VRBO
From $291 per night (USD)
VRBO
Private Vineyard
Bedrooms:
1
Bathrooms:
1
Sleeps:
3
Have your privacy to a home of your own with backyard firepit overlooking a vineyard. Less than .5 miles from downtown ...
From $291 per night (USD)
VRBO
From $267 per night (USD)
VRBO
Spacious and Comfortable Home in Saint Peters
Bedrooms:
3
Bathrooms:
3
Sleeps:
8
Elegant and spacious home in Saint Peters with plenty of room for family and children. Stay here if you're looking for a ...
From $267 per night (USD)
VRBO
From $1387 per night (USD)
VRBO
The Estate at Sunflower Hill Farm
Bedrooms:
3
Bathrooms:
5
Sleeps:
8
The Estate at Sunflower Hill Farm is a 5-Bedroom Luxury Farmhouse on 24 Acres of land. The property is a hidden gem in M ...
From $1387 per night (USD)
VRBO
From $229 per night (USD)
VRBO
Cozy Wine Country Home [ Lodging only ... this is not an event venue ]
Bedrooms:
2
Bathrooms:
3
Sleeps:
5
Guests are sure to enjoy a memorable stay in this fully furnished, 3 bedroom/2 bath ranch home property. The main/maste ...
From $229 per night (USD)
VRBO
From $259 per night (USD)
Expedia
1790's Renovated Barn, Main Street St. Charles, Hot Tub in private backyard!
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
The Red Barn Guest House is a beautifully remodeled home with amazing details that makes this vacation rental truly uniq ...
From $259 per night (USD)
Expedia
From $333 per night (USD)
VRBO
Wonderful Oak Log Home on the Mississippi River
Bedrooms:
2
Bathrooms:
2
Sleeps:
7
A piece of Heaven! Wonderful 2000 sq. ft., 1.5 story oak, log home overlooking (& direct access to) the Mississippi R ...
From $333 per night (USD)
VRBO
From $274 per night (USD)
Expedia
1870's Luxury Guest Cottage, Historic Downtown St. Charles, Mo.
Bedrooms:
2
Bathrooms:
3
Sleeps:
7
The Old Town Guest House is an upscale vacation home originally built in 1870 and beautifully renovated with tasteful an ...
From $274 per night (USD)
Expedia
From $275 per night (USD)
VRBO
The St. Charles Guest House, lovely historic home, fun for families and groups
Bedrooms:
2
Bathrooms:
3
Sleeps:
8
"The St. Charles Guest House" is a beautifully renovated and decorated home in the heart of Historic St. Charles, MO. Th ...
From $275 per night (USD)
VRBO
From $278 per night (USD)
Expedia
Springhurst Serenity: Fresh 4BR Getaway
Bedrooms:
3
Bathrooms:
4
Sleeps:
10
Welcome to our spacious and inviting getaway! Nestled in a serene neighborhood, our stunning house is the perfect destin ...
From $278 per night (USD)
Expedia
Click For Pricing
VRBO
Buried Deep in St Charles
Bedrooms:
3
Bathrooms:
4
Sleeps:
2
One room for rent for very short periods. Preferred rentals by employees of Siemon Co. Single bedroom and bathroom avai ...
Click For Pricing
VRBO
From $398 per night (USD)
VRBO
Saint Charles House Near Historic Downtown!
Bedrooms:
3
Bathrooms:
4
Sleeps:
9
Explore the St. Louis area from this vacation rental in Saint Charles, MO! Just 6 miles from the city’s historic downtow ...
From $398 per night (USD)
VRBO
From $151 per night (USD)
VRBO
Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
A cozy single-family home in the heart of Frenchtown in Saint Charles, MO right around the corner from Historic Main Str ...
From $151 per night (USD)
VRBO
From $281 per night (USD)
Expedia
Honky Tonk Hideaway
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
Welcome to the Honky Tonk Hideaway nestled near the historic charm of Main Street in Saint Charles! This inviting house ...
From $281 per night (USD)
Expedia
From $172 per night (USD)
VRBO
The Wild West Getaway- 204-1
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
Welcome to Cowboy, our charming, 2 bedroom/1 bathroom apartment located in the heart of historic St. Charles. Saddle up ...
From $172 per night (USD)
VRBO
From $153 per night (USD)
Expedia
Spacious 2 bed Townhome by StayLage
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
2 bedroom, 1.5 bath townhome available within walking distance of Streets of Saint Charles. Just south of I-70 Enjoy thi ...
From $153 per night (USD)
Expedia
From $149 per night (USD)
VRBO
Cozy Unit on Historic Main Street
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
ON MAIN ST NEAR EVERYTHING Discover your perfect getaway in charming St. Charles, right on historic Main Street! This i ...
From $149 per night (USD)
VRBO
From $210 per night (USD)
Expedia
Wentzville King Bed Walk to Downtown!
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
This charming unit is a perfect blend of comfort and style. The bedroom features a luxurious king-size bed, a cozy sitti ...
From $210 per night (USD)
Expedia
From $138 per night (USD)
VRBO
Private Basement - Two King Beds and Hot Tub
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Welcome to our private and cozy basement retreat with a Hot Tub! Our beautifully furnished basement unit is perfect for ...
From $138 per night (USD)
VRBO
From $199 per night (USD)
Expedia
The Maison Champignon
Bedrooms:
1
Bathrooms:
3
Sleeps:
6
The space Maison Champignon is a charming 3BR/1BA getaway with a warm French-Country feel, nestled in the heart of St. ...
From $199 per night (USD)
Expedia
From $188 per night (USD)
VRBO
Adorable 2 King Bed Frenchtown Home
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
You are going to love this stylish and well decorated home in St Charles. Well Stocked with all the amenities you will n ...
From $188 per night (USD)
VRBO
From $236 per night (USD)
Expedia
Completely Renovated Home in St. Charles, Missouri
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Welcome to your perfect getaway in St. Charles, Mo! Come enjoy this newly renovated charming three-bedroom, two-bathroom ...
From $236 per night (USD)
Expedia
From $178 per night (USD)
VRBO
Charming Historic Retreat in Old Town St. Charles
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Experience the charm of Old Town St. Charles in this cozy and beautifully restored home. Just steps from local shops, di ...
From $178 per night (USD)
VRBO
From $471 per night (USD)
Expedia
FALL SALE NOW | Private |Game Rm | Hot Tub | .67 acres |
Bedrooms:
4
Bathrooms:
4
Sleeps:
14
🌸 **FALL Sale Now On!** 🌸 Experience our hand crafted vacation rental featuring a modern kitchen with updated app ...
From $471 per night (USD)
Expedia
From $238 per night (USD)
VRBO
Spacious Historic Townhouse - Character for All
Bedrooms:
2
Bathrooms:
2
Sleeps:
8
This charming spacious historic townhouse is a completely renovated century-old duplex, near Historic Old Town St. Charl ...
From $238 per night (USD)
VRBO
From $141 per night (USD)
Expedia
Private walkout basement: 2 queen beds & full bath
Bedrooms:
1
Bathrooms:
2
Sleeps:
5
Relax at this peaceful place and safe neighborhood. You have the entire basement to yourself. This space includes a que ...
From $141 per night (USD)
Expedia
From $441 per night (USD)
VRBO
T's Luxury Pool, Hot Tub, Home Theater & Arcade House Prime - St. Louis Airport
Bedrooms:
2
Bathrooms:
4
Sleeps:
14
Welcome to your luxurious retreat! This spacious *4-bedroom, 2.5-bathroom home* is designed to provide you with unmatche ...
From $441 per night (USD)
VRBO
From $352 per night (USD)
Expedia
Walking distance to Historic Main Street, St. Charles, MO
Bedrooms:
3
Bathrooms:
3
Sleeps:
6
Welcome to your home away from home! This cozy 3-bedroom, 3-bathroom house is the perfect retreat for your stay in St. C ...
From $352 per night (USD)
Expedia
$4-bed house in Wentzville next to restaurants/event space/\Free food and drink\$
From $279 per night (USD)
VRBO
4-bed house in Wentzville next to restaurants/event space/\"Free food and drink\"
Bedrooms:
2
Bathrooms:
4
Sleeps:
10
Free food and drinks at local establishments with every booking!!! WELCOME to the THE ROSE! This 100 year old home in th ...
From $279 per night (USD)
VRBO
From $253 per night (USD)
Expedia
The Secret Sojourn | JZ Vacation Rentals
Bedrooms:
1
Bathrooms:
3
Sleeps:
8
THE SPACE Layout: 3 Bedrooms | 1.5 Bathrooms Master Bedroom - King Bed with ensuite half-bath for a private, relaxing ...
From $253 per night (USD)
Expedia
From $407 per night (USD)
VRBO
Vino Villa Wine Country Gem: Patio & Grill
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Close to Wineries, Hiking & Fishing | Game Room | Fire Pit Raise your glass and let the good times flow at this 3-bed, ...
From $407 per night (USD)
VRBO
From $179 per night (USD)
VRBO
'The Chardonnay Chalet' Defiance Studio Trail!
Bedrooms:
1
Bathrooms:
1
Sleeps:
3
Experience a unique getaway to the countryside with your family or significant other when you book this modern tiny home ...
From $179 per night (USD)
VRBO
From $177 per night (USD)
VRBO
‘The Merlot Bungalow’ Defiance Tiny Home on Trail
Bedrooms:
1
Bathrooms:
1
Sleeps:
3
Escape the hustle and bustle of St. Louis with a stay at this chic countryside vacation rental in Defiance, MO. 'Merlot ...
From $177 per night (USD)
VRBO
From $273 per night (USD)
VRBO
Charming 3-bedroom house with WiFi, AC in O'Fallon
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Make yourself at home in this 3-bedroom O'Fallon retreat. This charming house boasts 1 king bed and 2 queen beds, perfec ...
From $273 per night (USD)
VRBO
From $133 per night (USD)
VRBO
St. Peters Private Basement Guesthouse: Farm Views - Visit Family & Friends
Bedrooms:
1
Bathrooms:
1
Sleeps:
6
Wake up to pond views, open fields, and visiting wildlife. Enjoy a private entrance, fenced yard, and patio—just minute ...
From $133 per night (USD)
VRBO
From $661 per night (USD)
VRBO
Need an Elegant Escape?
Bedrooms:
5
Bathrooms:
5
Sleeps:
10
Nestled in the rolling hills of Missouri wine country is The Reserve at Augusta — a unique enclave meticulously reinvent ...
From $661 per night (USD)
VRBO
From $659 per night (USD)
VRBO
Hill Manor at the Crossroads of the Nation
Bedrooms:
3
Bathrooms:
6
Sleeps:
16
Large home for a family gathering or wedding entourage. Sleep everyone under one roof! Office with a private workspace i ...
From $659 per night (USD)
VRBO
From $200 per night (USD)
VRBO
Romantic Augusta Cottage w/ hot tub
Bedrooms:
1
Bathrooms:
1
Sleeps:
2
This cottage is designed to strengthen and refresh couples looking for a getaway from busy life. Relax in the comfortab ...
From $200 per night (USD)
VRBO
From $198 per night (USD)
VRBO
Peaceful & Cozy Stay
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Escape to tranquility just 1.1 mi from New Town St. Charles. Our home harmonizes convenience with comfort—3 beds, 2.5 ba ...
From $198 per night (USD)
VRBO
From $409 per night (USD)
Expedia
Charming 4BR near Convention Ctr., Main St, & LU -just 11 minutes to STL Airport
Bedrooms:
2
Bathrooms:
4
Sleeps:
8
St. Charles is known for its historic architecture, specialty stores and antiques, lovely parks, and various recreation ...
From $409 per night (USD)
Expedia
From $346 per night (USD)
VRBO
Charming open 4bd and screen-in porch! Sleeps 10!
Bedrooms:
2
Bathrooms:
4
Sleeps:
10
Minutes from LU, Mainstreet, Streets of St Charles & Ameristar! This beautiful home in a quiet neighborhood is central t ...
From $346 per night (USD)
VRBO
From $252 per night (USD)
Expedia
BACKYARD OASIS! Cozy and charming 60s Brick ranch with relaxing gazebo over pond
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
Charming home is updated with an open floor plan. Backyard has a relaxing gazebo overlooking pond. Pet ducks free range ...
From $252 per night (USD)
Expedia
From $330 per night (USD)
VRBO
Sage Haven Ranch Retreat, Yard, Fire Pit, BBQ, Office space, Close to shopping
Bedrooms:
2
Bathrooms:
3
Sleeps:
8
Rovvi Rentals is proud to present you with a premier STR in the heart of Saint Peters Missouri. We try our best to make ...
From $330 per night (USD)
VRBO
From $461 per night (USD)
Expedia
The Wild Rose Cottage in Historic Old St Charles
Bedrooms:
4
Bathrooms:
4
Sleeps:
12
Introducing The Wild Rose Cottage! This brand new beauty abounds with space and "Glam Cottage" charm. It is perfectly lo ...
From $461 per night (USD)
Expedia
From $346 per night (USD)
VRBO
Spacious, Beautiful St. Charles Home-Remodeled-Sleeps 10! New Patio!
Bedrooms:
2
Bathrooms:
3
Sleeps:
12
Bring the whole family to this great place with lots of room for fun. Centrally located in downtown St. Charles - walkin ...
From $346 per night (USD)
VRBO
From $343 per night (USD)
Expedia
Home Near Main Street-Covered Patio-Hot Tub!
Bedrooms:
2
Bathrooms:
3
Sleeps:
12
Have fun with the whole family at this stylish Home! Brand new everything! Upscale kitchen for making meals, 2 full bath ...
From $343 per night (USD)
Expedia
From $267 per night (USD)
VRBO
‘The Reubling House’ - Modern-Rustic Cabin!
Bedrooms:
1
Bathrooms:
1
Sleeps:
4
Brimming with scenic spots, vineyards, and St. Louis thrills, this sleek 1-bedroom + loft, 1-bath cabin offers a true ch ...
From $267 per night (USD)
VRBO
From $416 per night (USD)
VRBO
BEAUTIFUL Historic 3 Bedroom Upscale Guesthouse!!
Bedrooms:
2
Bathrooms:
3
Sleeps:
6
Spacious luxury three bedroom home in historic St. Charles. Minutes away from Main Street, French town, Streets of St. C ...
From $416 per night (USD)
VRBO
From $366 per night (USD)
VRBO
Casa de Saint Charles
Bedrooms:
3
Bathrooms:
6
Sleeps:
12
*HISTORIC MAIN STREET 5 miles away. 15-25 min to anywhere in St. Louis/St. Charles County* Enjoy a stylish experience a ...
From $366 per night (USD)
VRBO
From $286 per night (USD)
Expedia
Walk to St Charles Main St. Shops, Eateries & Bars!
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
The "Lion House" is a completely restored charming 1930s home located in the heart of St. Charles’ National Historic Dis ...
From $286 per night (USD)
Expedia
From $318 per night (USD)
VRBO
O'Fallon Edge Oasis- 4bd/3bt, Wooded Backyard, Office, Great Family Getaway
Bedrooms:
3
Bathrooms:
4
Sleeps:
10
Rovvi Rentals is proud to present you with a premier STR in the heart of O' Fallon Missouri. This house is centrally l ...
From $318 per night (USD)
VRBO
From $306 per night (USD)
VRBO
Dreamy St Charles Retreat w/ Furnished Patio!
Bedrooms:
2
Bathrooms:
3
Sleeps:
8
Gain access to the beauty of St. Charles when you stay at this historic vacation rental! A part of the National Historic ...
From $306 per night (USD)
VRBO
From $289 per night (USD)
VRBO
Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway
Bedrooms:
1
Bathrooms:
3
Sleeps:
10
**We are AirBandB Superhosts for 3 years running! Over 200, 5 Star Reviews!** The Blue Oak is nestled in the center of ...
From $289 per night (USD)
VRBO
From $345 per night (USD)
Expedia
New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!
Bedrooms:
2
Bathrooms:
3
Sleeps:
12
*Recently remodeled* beautiful 3 bed, 2 full bath home that offers more than 1,600 SF. The natural light and open floor ...
From $345 per night (USD)
Expedia
Click For Pricing
VRBO
PENTHOUSE 2BD2BTH PAC-MAN/ROKU
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
Welcome to our home away from home spacious quiet penthouse pac-man suite. Enjoy your stay! Booking Protection Guarantee ...
Click For Pricing
VRBO
From $133 per night (USD)
Expedia
Spacious Cottage on Main st- Near Downtown
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
MESSAGE FOR DISCOUNT ON SHORT STAY Welcome to our charming 2-bedroom, 1-bathroom unit on historic Main St. in the heart ...
From $133 per night (USD)
Expedia
From $229 per night (USD)
VRBO
Charming 2-Bed Brownstone in The Heart of New Town
Bedrooms:
2
Bathrooms:
2
Sleeps:
4
Our home is in the heart of New Town, just steps away from the coffee shop & restaurants! It's within 5 miles of histor ...
From $229 per night (USD)
VRBO
From $110 per night (USD)
Expedia
Business-Traveler Friendly 2-bedroom condo in fantastic Lake Saint Louis
Bedrooms:
1
Bathrooms:
2
Sleeps:
4
Your Lake Saint Louis adventure begins at this 2-bedroom condo. This charming property features 1 queen bed and 1 twin b ...
From $110 per night (USD)
Expedia
From $305 per night (USD)
VRBO
Groovy In-Laws Suite
Bedrooms:
2
Bathrooms:
2
Sleeps:
4
Welcome to the Groovy In-Laws Suite—a thoughtfully designed space that feels more like its own charming apartment than j ...
From $305 per night (USD)
VRBO
From $244 per night (USD)
Expedia
River Life Landing - Cozy, Relaxing home along Mississippi River - Grafton, IL
Bedrooms:
1
Bathrooms:
3
Sleeps:
6
Enjoy a riverside retreat in Grafton, Illinois! River Life Landing is a spacious, peaceful, cozy home featuring relaxing ...
From $244 per night (USD)
Expedia
From $242 per night (USD)
VRBO
Charming 2-bedroom townhome with a cozy fireplace in the heart of Grafton
Bedrooms:
2
Bathrooms:
2
Sleeps:
6
This Grafton townhome boasts 2 inviting bedrooms, and 3 bathrooms. Take a short stroll to the Grafton Winery & Brewhaus, ...
From $242 per night (USD)
VRBO
From $696 per night (USD)
VRBO
Grafton home located off main street.
Bedrooms:
2
Bathrooms:
5
Sleeps:
12
Welcome to Rafton Inn 3! Newly listed as of May 2025, We are thrilled to host you in our cozy space. We are located on ...
From $696 per night (USD)
VRBO
From $382 per night (USD)
VRBO
Charming upper level of 3-bedroom house in Grafton, IL
Bedrooms:
1
Bathrooms:
3
Sleeps:
6
Stay comfortably in Grafton at this 3-bedroom house, on the Upper Level. We offer to rent the upper level and lower leve ...
From $382 per night (USD)
VRBO
From $309 per night (USD)
VRBO
Grafton Getaway-Riverhouse....a waterfront property with bike trail in backyard
Bedrooms:
2
Bathrooms:
4
Sleeps:
14
Grafton Getaway - Riverhouse is the sister property to Grafton Getaway - Farm (23 acres with private fishing and wooded ...
From $309 per night (USD)
VRBO
From $184 per night (USD)
VRBO
Guest House 632 Summit Street
Bedrooms:
1
Bathrooms:
2
Sleeps:
6
Beautiful 2-story house located on the bluffs in the Christian Hill district of historic Alton, Illinois. Enjoy the beau ...
From $184 per night (USD)
VRBO
From $524 per night (USD)
Expedia
Historic 1830s Lodge/Cabin Overlooking Missouri River
Bedrooms:
4
Bathrooms:
5
Sleeps:
18
<p>Close to kayaking, birdwatching, and more, this pet-friendly vacation home brings it all within reach. Missouri River ...
From $524 per night (USD)
Expedia
From $615 per night (USD)
VRBO
RAFTON INN VACATION RENTAL
Bedrooms:
3
Bathrooms:
3
Sleeps:
12
Welcome to "Rafton Inn"- This overnight-stay is located in the heart of Grafton IL. You will be located right on Main St ...
From $615 per night (USD)
VRBO
From $263 per night (USD)
Expedia
Two bedroom, 2 1/2 bath Condo. Great River Views & Pool!
Bedrooms:
2
Bathrooms:
2
Sleeps:
4
This beautiful condo located at the Villas in Grafton, Illinois is the perfect place for family or a couple’s getaway we ...
From $263 per night (USD)
Expedia
From $366 per night (USD)
VRBO
River View TH w/ Patio- 1 block from Main St
Bedrooms:
2
Bathrooms:
3
Sleeps:
10
The Gray Pelican is on the bluffs where the Illinois and Mississippi River meet. This 3 bdrm/2 ba townhome (sleeps 10) i ...
From $366 per night (USD)
VRBO
From $241 per night (USD)
VRBO
Grafton Getaway-Cabin on 2 wooded acres just 1/2 mile from Main Street
Bedrooms:
1
Bathrooms:
3
Sleeps:
11
Grafton Getaway - Cabin is a 2019 renovated home originally built in 1900. The long driveway crosses a spring-fed creek ...
From $241 per night (USD)
VRBO

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Results: 114 Rentals